Aderans

[rdawg]

2013 is probably not realistic!

But I'd definitely think if Phase 3 is:

- 6 months --> we should have it by Dec 2014

- 12 months --> by June 2015

All Phase 2 studies will be completed in April 2013!

Uh man... the day I find out they're initiating Phase 3 I will cry

haha for sure, as in this case, it essentially guarentees a new product on the market within 2 years!

Any info you have on Bim's results? I swear they are very close to phase III as well.

I'd expect 2-3 companies to give us updates around Feb/march.

[Desmond84]

Wow so you're essentially telling me this could be released THIS YEAR if they fast track it?

obviously that would be europe I suppose, then by summer 2014 in NA.

wow we are close if this is true, Can't wait til we get another product to use! Just on Fin to transition me over.

2013 is probably not realistic!

But I'd definitely think if Phase 3 is:

- 6 months --> we should have it by Dec 2014

- 12 months --> by June 2015

All Phase 2 studies will be completed in April 2013!

Uh man... the day I find out they're initiating Phase 3 I will cry

[rdawg]

I saw jarjarbinx post this on another forum yesterday. I agree with him quite a fair bit! Imagine if Phase 3 ended up being 6 months, we'd definitely have ji gami availablle by Dec 2014!

"Aderans - could also be a major breakthrough. At minimum Aderans has a solid treatment better than anything on the market. I think they have a shot at being comparable to Histogen. They were producing good results and they were hoping to tweak their results in phase 2 studies. They are still working out the details and they have multiple phase 2 trials ongoing. They are almost done with phase 2 trials. We will be hearing news from them this February, and then it's onto phase 3 and then to market. I think that the results that they have already shown the world from the previous study ascertain that they will be bringing their treatment to market because their already publicized treatment results are already better than anything on the market and their treatment could be improved upon. In other words I have a hunch that their next round of results will be better than the last round of resuls. I also think that that one could use their treatment to get back a lot of hair and then add minoxidil or bimatoprost and improve on those results. Also, unless Follica shows back up in the picture Aderans will probably be the first of the new revolutionary treatments to hit the market - sometime in 2014. It's not out of the realm of possibility that Aderans could turn it's last study (Phase 3) that should start early 2013 into a 6-month study. If they do that then they could release their treatment in late 2013 somewhere in the world. Most likely their last study will be 12 months but it could be just 6 months since their early scientific work involved lengthy studies. Their phase 1 studies were almost 3 years long. The FDA can fast track Aderans treatment since Aderans has gathered a lot of data, they have a revolutionary treatment, their treatment will work on people who presently can't be treated, and people are clamoring for a treatment."

Wow so you're essentially telling me this could be released THIS YEAR if they fast track it?

obviously that would be europe I suppose, then by summer 2014 in NA.

wow we are close if this is true, Can't wait til we get another product to use! Just on Fin to transition me over.

[Desmond84]

No! we discussed this on another thread...Here's a snapshot of what's important:

"Finasteride has a flat dose response curve meaning taking 0.05mg, 0.2mg and 1mg daily would have exactly the same impact on your scalp DHT profile (which you guys have already realised)

Now, what that means is if you're going to experience sides on 1 mg, you're most likely going to experience sides on 0.05mg. Now, that being said, it may take a bit longer to surface, since its taking a longer period of time to reach a steady state (stabilise in your body). But if its going to happen, it will eventually happen!

So if you're just scared of getting sides and think that taking such a miniscule dose is going to stop that I can promise you that is not the case.

So, my honest opinion is that if you're desperate to try it but scared of sides, break a 1mg tablet into 4 pieces using a tablet cutter and take it 3 times a week (Mon, Wed, Fri). This should give you a good picture of how your body is going to react to this drug. AND BELIEVE ME IT"S STILL VERY EFFECTIVE

Dissolving it in ethanol and all that is fine, but why do it when there's no difference in your body's response. On top of that you're ingesting industrial grade alcohol for no reason at all!

With regards to taking it every other day or 3 times per week, it's safe to do so because of Finasteride's "pharmacological half-life". Now, please note that is different to the plasma half-life which is a measure of a drug's elimination from the body. (50% of finasteride is generally eliminated from your body within 2 hours)

The biological half-life on the other hand, is the point where its pharmacological effect (DHT reduction) is reduced by half. Now, for finasteride that is about 3-7 days, which allows you to take it 2-3 times a week rather than daily.

The reason why it has such a long biological half-life is because it is an IRREVERSIBLE inhibitor of 5-alpha-reductase, meaning that any alpha-reductase it binds to is pretty much deactivated and will no longer serve any purpose. Generally your body takes approximately 3-7 days to reproduce the same amount of 5-alpha-reductase and bring your DHT levels back up to normal. So, you can definitely take advantage of that and take it less often!"

If you want to read the whole discussion, read from Page 7-9. It covers everything

http://www.baldtruthtalk.com/showthread.php?t=10013&page=7

[yeahyeahyeah]

YEAHYEAHYEAH I'll be honest with you...there are 2 groups of fin users:

1) Can take and tolerate any dose of fin

2) Very sensitive to fin

Taking 1mg daily would give you 20% regrowth and halt all hairloss

Taking 0.25mg EVERY 4-7 days would probably give you 5-10% regrowth and halt/slow down your hairloss.

No one here is planning on taking fin forever! We just want to slow it down till one of these treatments come out in the next 2-3 years.

So, taking low doses would most definitely be a far better option than taking nothing at all.

That's the only reason why I'm taking it anyways. Otherwise changing your hormone profile is just ridiculous.

AND I'm the walking proof that it works! All I can do is share my experiences brother so someone else might benefit...

CHeers

But doesn't fin have a short half life?

[Desmond84]

Do you know anyone aside from you that is doing this with good results?

YEAHYEAHYEAH I'll be honest with you...there are 2 groups of fin users:

1) Can take and tolerate any dose of fin

2) Very sensitive to fin

Taking 1mg daily would give you 20% regrowth and halt all hairloss

Taking 0.25mg EVERY 4-7 days would probably give you 5-10% regrowth and halt/slow down your hairloss.

No one here is planning on taking fin forever! We just want to slow it down till one of these treatments come out in the next 2-3 years.

So, taking low doses would most definitely be a far better option than taking nothing at all.

That's the only reason why I'm taking it anyways. Otherwise changing your hormone profile is just ridiculous.

AND I'm the walking proof that it works! All I can do is share my experiences brother so someone else might benefit...

CHeers

[StinkySmurf]

Could this be good news for us???

http://dealbook.nytimes.com/2008/05/29/lichtensteins-steel-partners-ousts-board-of-japans-aderans/

Under NEW management, they might be forced to release their product after so many years!!!!

Nice find Desmond! No matter if it was from 2008, it was good info.

Here is the same story playing out exactly one year later in 2009, and this time they were successful in putting Joshua Schechter on the board. Joshua is now chairman of Aderans America. I guess he will be overall the person in charge of the new merged Bosley and Hair Club for Men businesses after Aderans closes the Hair Club deal next month.

[yeahyeahyeah]

Thinning just read it brother...

if its early stages I reckon just take 0.25mg of Finasteride ONCE A WEEK and see how you tolerate it. If you feel OK after 3 months then it's all good Keep taking it ONCE A WEEK until we get our hands on one of these cutting edge treatments.

Since its early days for you... taking it ONCE A WEEK will really slow things down for you

Hope that's helpful

Do you know anyone aside from you that is doing this with good results?

[Desmond84]

I saw jarjarbinx post this on another forum yesterday. I agree with him quite a fair bit! Imagine if Phase 3 ended up being 6 months, we'd definitely have ji gami availablle by Dec 2014!

"Aderans - could also be a major breakthrough. At minimum Aderans has a solid treatment better than anything on the market. I think they have a shot at being comparable to Histogen. They were producing good results and they were hoping to tweak their results in phase 2 studies. They are still working out the details and they have multiple phase 2 trials ongoing. They are almost done with phase 2 trials. We will be hearing news from them this February, and then it's onto phase 3 and then to market. I think that the results that they have already shown the world from the previous study ascertain that they will be bringing their treatment to market because their already publicized treatment results are already better than anything on the market and their treatment could be improved upon. In other words I have a hunch that their next round of results will be better than the last round of resuls. I also think that that one could use their treatment to get back a lot of hair and then add minoxidil or bimatoprost and improve on those results. Also, unless Follica shows back up in the picture Aderans will probably be the first of the new revolutionary treatments to hit the market - sometime in 2014. It's not out of the realm of possibility that Aderans could turn it's last study (Phase 3) that should start early 2013 into a 6-month study. If they do that then they could release their treatment in late 2013 somewhere in the world. Most likely their last study will be 12 months but it could be just 6 months since their early scientific work involved lengthy studies. Their phase 1 studies were almost 3 years long. The FDA can fast track Aderans treatment since Aderans has gathered a lot of data, they have a revolutionary treatment, their treatment will work on people who presently can't be treated, and people are clamoring for a treatment."

[Desmond84]

Desmond that article is from 2008, whatever difference it made is long gone now.

LOL I just realised....

GOD DAMMIT

[Desmond84]

Oh no! I just realised that article is dated in 2008!!!

LOL sorry guys

[youngsufferer]

Desmond that article is from 2008, whatever difference it made is long gone now.

[Desmond84]

Thanks for the contribution Desmond. I am new here but have been following this thread for a long time now.

I signed up to basically ask for advice on a short term regimen until one of the new technologies comes out in 2-5 years.

I just turned 25 and am thinning mildly. I was on Propecia and Rogaine and anti-SD shampoo for 5 months and that was working well but I quit because of the mild numbness side effects from Propecia, and the fact that I simply hated Rogaine.

I was hoping to get some advice as to how to hold on to my thinning hair for some time in my thread. I still look good and like I don't have MPB but would like to slow it down so any new treatments down the road can have a higher chance of success. Otherwise it will be a hair transplant, or a very short buzz (what the hell).

If anyone here who has followed the new technologies would like to give me some advice, here is the path to my thread:

"Men's hair loss" ----> "Introduce yourself and share your story" ----> "Asking for Advice for Short Term Strategy"

Thanks so much!

Thinning just read it brother...

if its early stages I reckon just take 0.25mg of Finasteride ONCE A WEEK and see how you tolerate it. If you feel OK after 3 months then it's all good Keep taking it ONCE A WEEK until we get our hands on one of these cutting edge treatments.

Since its early days for you... taking it ONCE A WEEK will really slow things down for you

Hope that's helpful

[Desmond84]

Could this be good news for us???

http://dealbook.nytimes.com/2008/05/29/lichtensteins-steel-partners-ousts-board-of-japans-aderans/

Under NEW management, they might be forced to release their product after so many years!!!!

[Thinning87]

Thanks for the contribution Desmond. I am new here but have been following this thread for a long time now.

I signed up to basically ask for advice on a short term regimen until one of the new technologies comes out in 2-5 years.

I just turned 25 and am thinning mildly. I was on Propecia and Rogaine and anti-SD shampoo for 5 months and that was working well but I quit because of the mild numbness side effects from Propecia, and the fact that I simply hated Rogaine.

I was hoping to get some advice as to how to hold on to my thinning hair for some time in my thread. I still look good and like I don't have MPB but would like to slow it down so any new treatments down the road can have a higher chance of success. Otherwise it will be a hair transplant, or a very short buzz (what the hell).

If anyone here who has followed the new technologies would like to give me some advice, here is the path to my thread:

"Men's hair loss" ----> "Introduce yourself and share your story" ----> "Asking for Advice for Short Term Strategy"

Thanks so much!