Aderans

[StinkySmurf]

It's not out of the realm of possibility that Aderans could turn it's last study (Phase 3) that should start early 2013 into a 6-month study.[/I]

Hey Desmond, I've been fishing a little, and it seems the final trial will be a different length. I also heard it will be six months instead of 12, but it's not clear if it will be Phase 3 or not. People tend to clam up when you use words like Phase.

I also heard it could be a different baldness pattern, but it's not clear if that was similar to other routine changes between trial criteria or if it was a major difference.

I'm just wondering if you folks think they would do a final 6 month Phase 2 trial that covers everyone before they move into Phase 3?

[Artista]

Desmond, I have to ask again..

"Replicel, Aderans, Follica & Intercytex have all folded!"
"It's all over I think! Baldness will not be cured in this decade"
Based upon WHAT exactly Desmond?

[StinkySmurf]

Before I explain the "rejuvenation thingy" problems again

Ok, I did my part so lets hear the rejuvenation thingy. What makes you think ARI doesn't have a marketable product?

[Kirby_]

BTW, lets await aderans phase 2 results, maybe the regrowth is promising.. and maybe it lasts for xx years, enough until the next sessions. its to early to tell at this point.

Don't loose your hopes yet guys..

I suppose objectively, ANY new super-treatment or procedure, should it reach the market should be warmly welcomed... I think many of us forget how little means we have to treat hairloss effectively.

[534623]

WTF!! - Are you serious or mimicking some of the haters?

Who are the haters? Am I a hater of novel approaches?

The guy on the left side is a normal young hairloss forums user like you. The guy on the right side is an abnormal hairloss forums user, because he always wants to know the FACTS about all these novel approaches – it’s me.
Nevertheless - both guys, as you can see in the pic, have the same problem; no matter how different they think about novel approaches. That means, BOTH would warmly greet such novel approaches; provided, their products work as promised.

You have to understand, that not every person out there in general or on hairloss forums is as “blue-eyed” than the other – bald or not. Sometimes they are not even interested to know WHEN something will hit the market; at first they are more interested about the WHETHER – whether or not something is working at all or whether or not there are any risks involved. Or whether or not something has at least the potential to work at all – before they get (over-)excited.

Anyway, as you can see, my tonsure area, for example, is still not slick bald per se; there are still lots of just miniaturized hairs.
So don’t you think that I too would rather WARMLY greet something like Aderans’ (new) “rejuvenation of existing hair follicles structures” idea, instead of doing (costly) hair transplants, to fill up all the bald areas with permanent und healthy terminal hairs producing follicles again?

So the question remains: do I believe in ARI’s old/new idea/approach?

Should I believe in ARI’s new idea? If YES, why? What are the FACTS?
Should I simply wait, instead of doing any hair transplants?
To avoid any loss of time, I have to find out IN ADVANCE whether or not something like ARI’s approach has at least the potential to work at all – in advance! That’s the point. At least, my standpoint.

[Boldy]

It's all over I think! Baldness will not be cured in this decade

We lost out!

I still have hope. and know everything is possible, with the right resources and knowledge. with that I know there are other ways as an alternative, but it will take much much work, efforts and a place to do it..

BTW, lets await aderans phase 2 results, maybe the regrowth is promising.. and maybe it lasts for xx years, enough until the next sessions. its to early to tell at this point.

Don't loose your hopes yet guys..

[Artista]

"Replicel, Aderans, Follica & Intercytex have all folded!"
Based on WHAT exactly?

[amibald]

If they're not using DP cells then there will not be DHT resistance! Their current treatment will probably only delay the inevitable!

Replicel, Aderans, Follica & Intercytex have all folded!

Histogen is all that's left to give us a slight regrowth before we lose it all within 5 years!!!

It's all over I think! Baldness will not be cured in this decade

We lost out!

Gho? 10char

[Kirby_]

Wait, I'm confused - is Aderans just the old Intercytex rebadged, and equally won't work/will never get released?!

[Jairus]

If they're not using DP cells then there will not be DHT resistance! Their current treatment will probably only delay the inevitable!

Replicel, Aderans, Follica & Intercytex have all folded!

Histogen is all that's left to give us a slight regrowth before we lose it all within 5 years!!!

It's all over I think! Baldness will not be cured in this decade

We lost out!

WTF!! - Are you serious or mimicking some of the haters?

[Desmond84]

If they're not using DP cells then there will not be DHT resistance! Their current treatment will probably only delay the inevitable!

Replicel, Aderans, Follica & Intercytex have all folded!

Histogen is all that's left to give us a slight regrowth before we lose it all within 5 years!!!

It's all over I think! Baldness will not be cured in this decade

We lost out!

[hellouser]

"The problem with the hair patch assay was it was not very translatable to the human condition, and early on we spent a lot of time looking at developing architecture that... err scaffolding... that we can put our cells in to try to orient the growth of hair follicles because despite all of the success that we are so proud of this is of limited utility in an aesthetic environment."

So there you go. They went with an approach they could make it through Phase 3 with on a $150 million dollar budget instead of going for something so complex as creating a follicle with a scaffolding because that involves aesthetic issues like the angle of hair growth that are an order of magnitude more difficult and these are not folks that want to go outside the company for money. This is a slightly down on it's luck $500 million dollar company where the majority of shares are held by just three parties, and lets face it, they don't want to go after the market of people that are willing to have surgery... thats the whole point of the opening chart where they say they want to be the botox of hair. In other words, they want to reach economies of scale. They are not looking for a solution that involves needing a bunch of artist grade plastic surgeons. They're looking for something thats mass market at least initially.

Yup. Its a different approach. The investors looking to cash in on this are probably anxious as hell to get the ball rolling and watch their bank accounts explode. I've already started saving up cash for any procedure necessary. At the moment I'm set to go with Gho in the meantime just for my hairline and thicken up whatever else on the crown, but if Aderans has a commercial product like they said they would by Q1 of 2014, those investors will be happy to know I will easily hand over even a large sum of money just for their procedure. And I don't care what it costs... its my psychological health, that DOESNT have a price. These guys are out to make a killing.

Having said that.. is Aderans a publicly traded company? Cuz holy crap I'd like to buy some stock.

[StinkySmurf]

Before I explain the "rejuvenation thingy" problems again, could you please explain more specific the neogenesis thingy, and WHAT EXACTLY is he saying (simply say what he is saying - he doesn't say that much about it!) concerning the "difficult due to the aesthetic issues" thingy. This would be really great.

"The problem with the hair patch assay was it was not very translatable to the human condition, and early on we spent a lot of time looking at developing architecture that... err scaffolding... that we can put our cells in to try to orient the growth of hair follicles because despite all of the success that we are so proud of this is of limited utility in an aesthetic environment."

So there you go. They went with an approach they could make it through Phase 3 with on a $150 million dollar budget instead of going for something so complex as creating a follicle with a scaffolding because that involves aesthetic issues like the angle of hair growth that are an order of magnitude more difficult and these are not folks that want to go outside the company for money. This is a slightly down on it's luck $500 million dollar company where the majority of shares are held by just three parties, and lets face it, they don't want to go after the market of people that are willing to have surgery... thats the whole point of the opening chart where they say they want to be the botox of hair. In other words, they want to reach economies of scale. They are not looking for a solution that involves needing a bunch of artist grade plastic surgeons. They're looking for something thats mass market at least initially.

[534623]

My interpretation is that they put neogenesis aside because they felt like it was much more difficult due to the aesthetic issues, and so instead they went for rejuvenating follicles.

Right - he is basically talking about TWO different approaches:

- follicles neogenesis (implants of "hair seeds" to produce brand new hair follicles from scratch);

- injections of different cell types (similar approach) to "rejuvenate" existing hair structures in the (balding) scalp.

Before I explain the "rejuvenation thingy" problems again, could you please explain more specific the neogenesis thingy, and WHAT EXACTLY is he saying (simply say what he is saying - he doesn't say that much about it!) concerning the "difficult due to the aesthetic issues" thingy. This would be really great.

[StinkySmurf]

Now I'm asking the 4th time: what exactly is Dr. Washenik saying in this video concerning this problem, or in other words:
why did they cast away their initial idea of creating thousands of brand new follicles from scratch?
Is it really so difficult to watch the video and to report here what exactly he is saying concerning this issue? I even described with a pic where in the video you can easily find this point. I mean, WHAT FOR is this thread? Discussing WHEN they will sell you "the cure"?

Yes, I could see that you have a point. I just wasn't sure where in the video you were talking about, and I got really busy, but I know exactly the part you're talking about now. I thought those pictures looked familiar

Yes, I thought this part was crucial. My interpretation is that they put neogenesis aside because they felt like it was much more difficult due to the aesthetic issues, and so instead they went for rejuvenating follicles. Thats why he says this will only work on people with miniaturized follicles like with male and female pattern baldness right after that, but I guess my question for you is why do you think it doesn't work just because it's not neogenesis?