CB-03-01 - new antiandrogenic

[LMS]

Is it worth taking if I'm already on RU?

They're both topical anti androgens. The only reason you'd want to go on CB is if you're getting sides on RU (like I do, much less than fin sides tho).
Stacking them together would yield little improvement over one.

[Scalpology]

Is it worth taking if I'm already on RU?

[LMS]

Sorry but there are really no vehicle issues for CB.. The problem is the price, not the vehicle. PG/ETH is completely fine as a vehicle only thing that isn't known is the stability but you can make daily batches to cope with that. You really need to use at least like a 3% concentration though and preferably 5%.

isnt the permeability of pg/eth pretty bad though. i believe cosmo released studies showing (on cadaver skin) that penetration was like many times better with oleyl alcohol.

i think some sort of solvent or a combination is needed. dmi/nmp/oleyl. dmso would almost definately work though no practical

price is also a huge factor. price im willing to pay for side effect free aa.

[Swooping]

Vehicle issues really is the situation, Desmond seemed to have found a proper one but it was IMO too complex for the average person to put together(it was like 10 different chemicals).

If they put together something proper it'll be great to get it earlier, i'm very interested in seeing their phase I results or Phase II results next year though.

Sorry but there are really no vehicle issues for CB.. The problem is the price, not the vehicle. PG/ETH is completely fine as a vehicle only thing that isn't known is the stability but you can make daily batches to cope with that. You really need to use at least like a 3% concentration though and preferably 5%.

[Paul73]

Vehicle issues really is the situation, Desmond seemed to have found a proper one but it was IMO too complex for the average person to put together(it was like 10 different chemicals).

If they put together something proper it'll be great to get it earlier, i'm very interested in seeing their phase I results or Phase II results next year though.

rdawg, thanks for the answer.

i agree that the vehicle is the issue here, but thatīs why i asked for Hellouser update. If i am not wrong he is using CB with good results.

Maybe when phase II trials for hair loss start we will know which vehicle Cosmos is using.

Hey Hellouser, can you comment about your actual status on CB?

Thanks guys!

[rdawg]

If CB-03-01 is already for sale at Kane, why should we wait for Cosmoīs trials?

Isnīt Hellouser using CB with great success? Why not follow his protocol to prepare it right now?

BTW, Hellouser. are you still using CB? Could you update us about your recent results on it?

Iīd appreciate your feedback. Thanks!

Vehicle issues really is the situation, Desmond seemed to have found a proper one but it was IMO too complex for the average person to put together(it was like 10 different chemicals).

If they put together something proper it'll be great to get it earlier, i'm very interested in seeing their phase I results or Phase II results next year though.

[rdawg]

This, along with BIM seems clearly on track for release. It's a very good sign when the product is already released/about to be released for a different situation.

BIM will be done phase IIb by january, likely moving on barring massive side effects(or if it doesnt work enough for them)

CB looks like it wont even need phase IIb given it's more of a product similar to fin, but it's an interesting product in that it can be used alone with seemingly no side effects OR it can be stacked on top of fin(for aggressive sufferers) to give an even better result.

Seems likely we'll have 1-2 new products by 2016, albeit they wont be cures, but they'll be new solutions.

[Seuxin]

Paul73,

Yes, you could buy CB-03-01 on kane, but you need to have the good vehicle with it.
In addition, CB-03-01 is heay heavy higher price !!! :\

[Denda]

I agree, if they design it to be applied via pulse therapy the atrophy should be avoided

[Paul73]

If CB-03-01 is already for sale at Kane, why should we wait for Cosmoīs trials?

Isnīt Hellouser using CB with great success? Why not follow his protocol to prepare it right now?

BTW, Hellouser. are you still using CB? Could you update us about your recent results on it?

Iīd appreciate your feedback. Thanks!

[Atum]

Didn't Kane shop said last year in dec. or something like that they would release a cream or gel in 3-4 months time? Where the heck is it?

[stan]

How did the acne product go so fast from IND to phase II? If you look at the alopecia product, the timeline goes from IND to a long time in proof of concept. Is proff of concept the same as phase II or I? Either way I'm not sure why people are saying 3-5 years, it seems more like 2 more for phase 1, another 2 probably for phase 2, and maybe another for phase 3, and then putting it out to market after that. 6-8 seems more realistic. And that's if this BS even works, they compare it to flutamide on here, didn't people try that with no success? Also, I doubt there's any great mystery to the vehicle, they are just using anhydrous solution, I'm sure if this was really a bette treatment than propecia then people would have seen results by now. Wouldnt put my hopes on this stuff.

i think they are done with phase I and in phase II already, acc to a guy who contacted people at cosmo. can you please tell me if there was any study etc that shows that cb has been more effective than fin, i mean a lot of people here say that it would be like topical fin but better, but based on what?

[sdsurfin]

How did the acne product go so fast from IND to phase II? If you look at the alopecia product, the timeline goes from IND to a long time in proof of concept. Is proff of concept the same as phase II or I? Either way I'm not sure why people are saying 3-5 years, it seems more like 2 more for phase 1, another 2 probably for phase 2, and maybe another for phase 3, and then putting it out to market after that. 6-8 seems more realistic. And that's if this BS even works, they compare it to flutamide on here, didn't people try that with no success? Also, I doubt there's any great mystery to the vehicle, they are just using anhydrous solution, I'm sure if this was really a bette treatment than propecia then people would have seen results by now. Wouldnt put my hopes on this stuff.

[FearTheLoss]

Thanks for posting. I believe that treatments more effective than Propecia and Avodart will be available within the next few years.

35YrsAfter also posts as CITNews and works at Dr. Cole's office - forhair.com - Cole Hair Transplant 1070 Powers Place Alpharetta, Georgia 30009 - Phone 678-566-1011 - email 35YrsAfter at chuck@forhair.com
The contents of my posts are my opinions and not medical advice. Please feel free to call or email me with any questions. Ask for Chuck

Correct me if I'm wrong, but they finish POC in March of 2015, so we could see this hit the market by the end of 2016, baring they get the results they want in POC.

CB won't need a phase IIb? Also, this could be released overseas in 2015?

[35YrsAfter]

Update from Cosmo.

http://www.cosmopharma.com/~/media/F...25JAN13_v5.pdf

Thanks for posting. I believe that treatments more effective than Propecia and Avodart will be available within the next few years.

35YrsAfter also posts as CITNews and works at Dr. Cole's office - forhair.com - Cole Hair Transplant 1070 Powers Place Alpharetta, Georgia 30009 - Phone 678-566-1011 - email 35YrsAfter at chuck@forhair.com
The contents of my posts are my opinions and not medical advice. Please feel free to call or email me with any questions. Ask for Chuck