CB-03-01 - new antiandrogenic

[burtandernie]

As an added benefit I think its possible CB 03 01 could be used to prevent unwanted hair growth. I would be curious to see how it does on just body hair or facial hair if it really interferes with both T and DHT in a powerful enough way it should have some effect. What happens to body/facial hair if you not only significantly lower DHT but also T does hair growth stop/slow or unaffected? I am curious to see that.

[yan]

Salix Pharmaceuticals to Combine with Cosmo Technologies to Form Salix Pharmaceuticals, plc

http://www.cosmopharmaceuticals.com/news/press/2014/2014-07-09.aspx

After the deal, cosmo owns 19.4 million shares of Salix, worth at $2.7 billion.

The cosmo share price is exploding. Around 90% rise in only 3 months and 200% rise in the last year.

I think these are all good signs. In most cases, when cosmo started developing a drug, it made it to market. They are very well capitalized, so from the financial part, things look very good. The risk is very low that they get bought up per example.

[rdawg]

CB all over the last 2 years at numerous forums, along the right ingretients to penetrate the scalp. Nothing has come out of it

I've never actually seen a member using it with the proper vehicle though, it's my understanding many of the vehicles members were using werent actually penetrating the scalp and that the vehicle is slightly more complex than just ethanol for example.

Great news that was posted above this comment though, this drug like Propecia was(and BIM was), is about to get approved for something else, very very likely this gets approved for hairloss as well barring very poor results, the next year will be very interesting.

Personally, I'm waiting to see Phase I/II hairloss trial results, if they're promising I'll be jumping on band wagon right away and stack this on top of FIN.

[kmit028]

There is a newly found vehicle that may work:

NMP or DMI + ethanol + glycerol or PG or BG

NMP - http://www.hairlosshelp.com/forums/m...&enterthread=y

Use NMP to dissolve CB, then just use the 70/30 or 80/20 vehicle of ethanol + glycerol/PG/BG

Also have a look here

http://www.hairlosshelp.com/forums/messageview.cfm?catid=7&threadid=111881&enterthread=y

[burtandernie]

Of course its going to be a long wait, but less of wait than some of the other stuff hyped up around here. The one thing I worry about CB is just the cost of this once if it does get finished. Its going to cost a fortune to make up for getting through the FDA.
Something will come out of it once it gets approval and you can buy it knowing that its proven and formulated to work

[clarence]

CB all over the last 2 years at numerous forums, along the right ingretients to penetrate the scalp. Nothing has come out of it

[joachim]

thanks lilpauly. but what does it mean exactly? ok, a successful phase 2 for acne completed, but the hairloss version is still more than 3 years away, if not more. no?

[lilpauly]

Cosmo announces successful conclusion of acne Phase II trial and agreement with Valeant to continue developing CB-03-01 in house

Lainate, Italy – July 8, 2014 – Cosmo Pharmaceuticals S.p.A. (SIX: COPN) today informed that it had successfully concluded the phase II acne trials of CB-03-01 and that, prior to the upcoming end of phase II meeting with the FDA, both Cosmo and Valeant Pharmaceuticals International, Inc., the licensee (NYSE / TSX: VRX), had agreed that it was preferable for both parties for Cosmo to continue developing the drug. Consequently both Cosmo and Valeant agreed to unwind the present agreement and replace it with an agreement granting Valeant a right of first refusal should Cosmo decide to license out the drug after completing its development.Alessandro Della Chà, CEO, commented: “I am very pleased by the results of this phase II, and even more pleased that Cosmo can continue developing the products in-house, leveraging on all the accumulated know how. Their potential is very significant, so the retention of the rights now allow us to create a stronger franchise in the derma field. Together with CB-03-01 we now have 5 products in clinical development. Given our strong financial position and in-house expertise, we are well equipped to exploit the potential of this rich pipeline for the benefit of patients and shareholders”."

http://www.cosmopharma.com/news/press/2 ... 07-08.aspx

[joachim]

hey guys. wasn't kane planning to bring a gel or nano-vehicle for cb? wasn't kane able to develop it or what? does anybody know more about kane's team? how many people are working there? are these professional chemists or what kind of guys are they?

i just wondered... are we really supposed to wait for cosmo's official release of their cb?
can't we just find a company (some chemists professionals) and pay them some money to help us with the vehicle? what about crowdfunding? i don't think that more than 100.000 are required for that mission. this would be an easy goal to crowdfund, and could bring us CB three years sooner. who knows for how long cosmo will be dancing around with their phases. so, do we really just have to wait all those years?

[Paul73]

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[Paul73]

As has been mentioned numerous times; Iron Dragon does NOT reveal purity tests of their CB-03-01 compound. Make of that what you will.

Thank you. I confess i didn´t do the ideal research to know about that.

Please, do you mind to comment about your recent experience with CB? Do you believe that you are using a efficient vehicle? I´d appreciate your feedback on it. I imagine other friends here would like to know about that too. Sorry if you already detailed it.

Thanks!

[hellouser]

What about CB-03-01 pre-made solution from Iron Dragon?

They are selling it since 2013. Has anybody tried it?

As has been mentioned numerous times; Iron Dragon does NOT reveal purity tests of their CB-03-01 compound. Make of that what you will.

[Paul73]

What about CB-03-01 pre-made solution from Iron Dragon?

They are selling it since 2013. Has anybody tried it?

[torontostringer]

can i mix this into minox and leave on the shelf or should i store it in the fridge?

[burtandernie]

If this BS works? How is something going through trials to prove it works at the highest standards in existance any kind of BS compared to the huge list of previous topicals where the company just says it works maybe with a small study to support it? Something going through trials is a different league of proof than anything else. If it doesnt work it will be shown and they wouldnt even be going to further trials and its already far enough along in acne to be pretty sure it works.
They will find a vehicle that works or it will never come out I guess. Some small early study said it was about twice as strong as fin, but finding the right dose if its higher might do better who knows. You dont know anything until they go through this long process and prove it