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Even multi-nationals seek investors for big projects, to try and spread the risk. Given that Aderans will have to spend anywhere from $200M to maybe $500M by the time they're done to commercialise this technology, I'm not at all surprised they are seeking investors.
And let's face it, if it works, ARI won't care if they've only got a 50% stake. 50% of the cash an effective baldness treatment is going to make will still be enough to set the entire lot of them up for life.
The directional thing is interesting, because rumours and photographic evidence have definitely suggested ARI are having problems with directional growth. This in turn definitely suggests de novo growth and not rejuventation (or at least not exclusively rejuvenation).
This may have something to do with what Replicel saw in their mouse models - when there were no existing follicles around they grew de novo follicles, but when there were existing follicles, the cells migrated into the follicles and rejuvenated them. Unfortunately, of course, Replicel's results when they transferred from mice to humans were less than impressive to say the least...Comment
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That's a good point, gmonasco. I didn't think of it that way, but it's certainly possible.
Also, Pate: You're definitely right about the direction thing, which is what makes this so confusing. Some indications point to no direction problems, while others point to direction problems. I wonder if whether or not follicles are created de novo depends on the degree of hair loss?
Hopefully Aderans has been keeping close tabs on the answers to these questions and feels like sharing soon.... ugh, the wait is so frustrating! Mostly because we're never surprised with truly good news...
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I'm actually contemplating on sending this link to them via email. Would be nice if somebody from the company registered on the forum, and gave us updates.
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Aderans at ISHRS
I don't get this...Aderans were due to present at the ISHRS event which has now been and gone right? So did they cancel and not present? Cos why else hasn't their presentation been released?
This is where I get a bit frustrated with Spencer, I mean this is his job, why wasn't he at the ISHRS? Surely he has enough contacts to get an invite? It seems from the live shows as if he just gave up instead and decided to promote FUE and f***ing head razors! If he has that guy selling those things on the show again I'll stop listening!Comment
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Dan & Desmond...any suggestions? Re-measuring and making my own capsules isn't an option. While studying for the boards, don't have a few hours to devout to do this. Should I just suck it up and take 1mg. Would it be bad, if jumped down to 0.5mg next month?
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I'm going to agree PARTIALLY. Spencer should get some kind of VIP pass for these kinds of events, he's basically an ambassador to the male balding community with a fairly active community in the forum. However, it would cost him some cash in airfare and accommodations so I wonder if its worthwhile for him to do so. However, I would like to see some kind of forum presence from Spencer and answer some simple questions like this; why couldnt he make it to the ISHRS? He'd definitely create some buzz and generate a little bit of traffic if he kept the public up to date on the event.Comment
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Hey JJ,
If you really want to do it the easy way, take 0.25mg (a QUARTER) every other day just to see how you feel on it. The trouble is if go on 1 mg daily and you get sides, it will take around 2 weeks for them to subside, making it very difficult to focus on your exams. Don;t worry about dissolving it and stuff, just cut it in quarters and take it every other day. That should take your mind off your hair and hopefully slow down the onset of sides if its going to happen.
Hope thats helpful.
Goodluck with your exams brother!
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I can't help thinking about the reports from a couple of people who contacted the Aderans clinical trial sites and were told that they were recruiting for phase III. I know that there was a lot of speculation over this but the more I think about it I can't get over the fact that there is no reason for those clinical test sites to lie.
They are independant clinical testing sites, they aren't owned by Aderans, they get nothing for lying about the progress of trials, plus even if Aderans did own them what would be the point in lying to potential test subjects?
So then there's the idea that the people just got the facts wrong or were confused. I don't think this is likely, their business is carrying out clinical trials, it would come across as unprofessional and deter clients if they had uninformed staff giving out incorrect information. Also I remember reading that one woman was very specific - she actually said something like "Yes, it's for phase III, the last phase before the product goes to market".
So the final consideration is whether or not the person posting the information was lying - I can't believe that a user of this forum would want to do that to the other forum users, it would just be mean! Also I believe one of the people was you wasn't it Desmond? and from what I've read of your posts you seem very sensible and informed.
They aren't expected to finished phase II til end of Q1 2013 but this was a pre-screening wasn't it? They could just be getting people ready and not actually starting the trial yet and therefore they haven't made an announcement. Also I presume that Aderans timeframe for the treatment process is much like Replicel - they take the sample of follicals from the patient and then have to culture it for 3 months before injecting the cells. So they could've recruited subjects and be getting them ready to take the sample at the end of the year, culture it over the first 3 months of 2013 and then they'll be ready to start the new trial properly as the phase II ends. I know I'm majorly speculating now but I'm just trying to think about how they might have indeed recruited for phase III but not felt the need to announce it yet.
So anywayz I just wanted to say all this cos it's been going round and round in my head, really wish we hada got some confirmation from Aderans following their presentation at ISHRS. Like Desmond said though, I'm sure if there was anything really good to say they woulda said it to everyone by now. So I just don't know! It's doing my head in!Comment
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Hey UK, I totally sympathize. I know I get really worked up over every small shred of hope that we're able to dig up. I know that I wasn't lying, and I'm confident that hellouser wasn't lying either. Still, I'd say the chance that the people on the phone made a mistake is pretty high. I say that because usually when it looks like we're about to get good news, we get the exact opposite.... and I can't bring myself to believe that Aderans is actually starting Phase 3. We unfortunately never get news like that in the hair loss industry...
Hopefully more people call and more people ask Spencer to help us get a concrete answer to stop all the speculation.Comment
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