Aderans

[Artista]

Hi Joker, thanks for asking...To clarify..The representative I spoke to did not speak of which phase testing that it was. She just told me that they and the rest of the clinics had completed enrollment.
What I mentioned was that online it it showed to be a Phase 2 enrollment.
AS you have said,,I have not been following the thread too closely so, maybe it is a Phase 3 ..(frustrating for us)

[Joker]

No problem, Artista. Thanks for the answer! Just trying to keep the conversation going until we hear some more information...

[Desmond84]

End of Phase 2

Hey guys,

I might have some great news!

It seems like ALL of Ji Gami 12 months trials have now completed. FINALLY over 10 Phase 2 trials have ended!!!

They added one last 6 month trial in June 2012 which is set to complete in April 2012! This is the CN combination which according to the Aderans Timeline graph is the one they will use in Phase 3.

Now, we have to speculate why they're doing it only for 6 months and not 1 year? (expert opinions are welcome)

My guess is while this mini-study is ongoing they're gearing up to write up their Phase III study protocols and submit it to FDA and ethics committees. At the same time in the next month or two they will begin recruiting over 500 patients for the Phase III trial.

Hopefully, Phase III should start in June 2013 and end sometimes in September 2014.

FDA approvals generally take around 6 months, which means that by March-April 2015 we can start lining up and get our hairs in order once and for all!

[rdawg]

Hey guys,

I might have some great news!

It seems like ALL of Ji Gami 12 months trials have now completed. FINALLY over 10 Phase 2 trials have ended!!!

They added one last 6 month trial in June 2012 which is set to complete in April 2012! This is the CN combination which according to the Aderans Timeline graph is the one they will use in Phase 3.

Now, we have to speculate why they're doing it only for 6 months and not 1 year? (expert opinions are welcome)

My guess is while this mini-study is ongoing they're gearing up to write up their Phase III study protocols and submit it to FDA and ethics committees. At the same time in the next month or two they will begin recruiting over 500 patients for the Phase III trial.

Hopefully, Phase III should start in June 2013 and end sometimes in September 2014.

FDA approvals generally take around 6 months, which means that by March-April 2015 we can start lining up and get our hairs in order once and for all!

wouldnt mind an official update though, this silence isn't comforting. Hoping for something by the end of the year.

[hellouser]

Hey guys,

I might have some great news!

It seems like ALL of Ji Gami 12 months trials have now completed. FINALLY over 10 Phase 2 trials have ended!!!

They added one last 6 month trial in June 2012 which is set to complete in April 2012! This is the CN combination which according to the Aderans Timeline graph is the one they will use in Phase 3.

Now, we have to speculate why they're doing it only for 6 months and not 1 year? (expert opinions are welcome)

My guess is while this mini-study is ongoing they're gearing up to write up their Phase III study protocols and submit it to FDA and ethics committees. At the same time in the next month or two they will begin recruiting over 500 patients for the Phase III trial.

Hopefully, Phase III should start in June 2013 and end sometimes in September 2014.

FDA approvals generally take around 6 months, which means that by March-April 2015 we can start lining up and get our hairs in order once and for all!

Correct me if I'm wrong, but didnt a member on this forum who is a pharmacist mentioned that an application for approval from the FDA can be filed some time during the Phase III trials which would bring back the target to their projected date of 2014?

[Joker]

Desmond: That new trial has actually been up for awhile (I thought everyone was aware of it). I'm not really sure what it means. The shorter duration is curious, as is the fact that it has less participants than the first CN trial (the one that has 100 participants). I just don't think we should get our hopes up that Phase 3 is starting soon without official word from the company. We don't know that this Phase 2 is the last Phase 2. We also don't know if the Phase 2 results have been good enough to move to Phase 3. There's just too many inconsistencies between the clinical trial sites, clinicaltrials.gov, the June 2010 presentation, the press releases, etc.

The frustrating thing is our only indication of efficacy came from the first 3 trials with 20-30 participants. 2.5 years have elapsed since then, and we've been given no new information whatsoever. I have no idea why Aderans has chosen to be so silent. Is it a reflection of their results? The fact that 8 months have gone by since their last update is really concerning to me.

I want to be positive, but once again... this industry just never seems to reward people for being optimistic.

Hellouser: I remember he said that Phase 4 was instituted after products were put on the market, but I don't remember anything about filing for Phase 3 early. Hopefully. That would be great news. But once again, until we know if Aderans has the funding/success rates to move forward with Phase 3 it's all pure speculation.

[534623]

We don't know that this Phase 2 is the last Phase 2. We also don't know if the Phase 2 results have been good enough to move to Phase 3. There's just too many inconsistencies between the clinical trial sites, clinicaltrials.gov, the June 2010 presentation, the press releases, etc.

The frustrating thing is ...

Come on – why are you waiting for Aderans, when a far better hair follicle stem cells cure already existis?

Google “Dr. Nigam world's first stem cell hair clinic, Mumbai, India“ and you will find brand new insights by Dr. Nigam himself. For example:

Posted today by Dr. Nigam:

Since you might be new to Stem Cell Hair Multiplication, let me clear you that Stem Cell Hair Multiplication are not 100%. Its an evolving research. We use a combination of Stem Cell Hair Multiplication plus traditional FUE(specially for the hair line). Regarding the weight-loss clinic under Dr.Nigam Brand is run by my wife. Since last 5 years, my research is totally focused on Stem Cell Hair Multiplication. I would appreciate if you confirm your perception before speculating on anyone and passing a judgement. You are cordially invited to my clinic or talk to my patients and see for yourself before-after results of Stem Cell Hair Multiplication. I will be shortly posting my results on xxxx forum. I am also inviting patients for third stage of Stem Cell Hair Multiplication WITH differentiation of Stem Cell into Hair Follicles for clinical trials...you are welcome. (This will be the FIRST AUTOLOGOUS ADULT STEM CELL Clinical Trial on Humans for differentiation of Stem Cell into Hair Follicle on Humans from February 2013) Adreans Research Clinical Trials are on Stem Cell Hair Multiplication and not on Differention into Hair Follicles.

Thank You,
Dr.Vivek Nigam.

Where is the difference between "Stem Cell Hair Multiplication" and "Stem Cell Differentiation into Hair Follicles" ?

[UK_]

Posted today by Dr. Nigam:

Since you might be new to Stem Cell Hair Multiplication, let me clear you that Stem Cell Hair Multiplication are not 100%. Its an evolving research. We use a combination of Stem Cell Hair Multiplication plus traditional FUE(specially for the hair line). Regarding the weight-loss clinic under Dr.Nigam Brand is run by my wife. Since last 5 years, my research is totally focused on Stem Cell Hair Multiplication. I would appreciate if you confirm your perception before speculating on anyone and passing a judgement. You are cordially invited to my clinic or talk to my patients and see for yourself before-after results of Stem Cell Hair Multiplication. I will be shortly posting my results on xxxx forum. I am also inviting patients for third stage of Stem Cell Hair Multiplication WITH differentiation of Stem Cell into Hair Follicles for clinical trials...you are welcome. (This will be the FIRST AUTOLOGOUS ADULT STEM CELL Clinical Trial on Humans for differentiation of Stem Cell into Hair Follicle on Humans from February 2013) Adreans Research Clinical Trials are on Stem Cell Hair Multiplication and not on Differention into Hair Follicles.

Thank You,
Dr.Vivek Nigam.

^^^^why dont you start a new thread about that? It will give the whole website something to laugh about.

And they'll also learn never to take advice off 534623.

He is a doctor who has apparently cured hair loss, yet can't even manage to spell the word differentiation correctly.

[534623]

And they'll also learn never to take advice off 534623.

He is a doctor ...

That's right. That's the reason why I wrote it right ...

Where is the difference between "Stem Cell Hair Multiplication" and "Stem Cell Differentiation into Hair Follicles" ?

[UK_]

That's right. That's the reason why I wrote it right ...

Your English is just as shit, read this back to yourself:

"Come on – why are you waiting for Aderans, when a far better hair follicle stem cells cure already existis?"

[534623]

He is a doctor who has apparently cured hair loss, yet can't even manage to spell the word differentiation correctly.

Here you'll find another such example ...

http://www.woodstechnique.com.au/

The guy says he is the inventor of "BOBY Hair to Scalp Transplantation (BHT)".

What is "Boby Hair" ??

[UK_]

Hey guys,

I might have some great news!

It seems like ALL of Ji Gami 12 months trials have now completed. FINALLY over 10 Phase 2 trials have ended!!!

They added one last 6 month trial in June 2012 which is set to complete in April 2012! This is the CN combination which according to the Aderans Timeline graph is the one they will use in Phase 3.

Now, we have to speculate why they're doing it only for 6 months and not 1 year? (expert opinions are welcome)

My guess is while this mini-study is ongoing they're gearing up to write up their Phase III study protocols and submit it to FDA and ethics committees. At the same time in the next month or two they will begin recruiting over 500 patients for the Phase III trial.

Hopefully, Phase III should start in June 2013 and end sometimes in September 2014.

FDA approvals generally take around 6 months, which means that by March-April 2015 we can start lining up and get our hairs in order once and for all!

Desmond, I appreciate your help and your information, but did you mean to say their final clinical trial which commenced in June 2012 is targeted for completion at April 2013?

Also, what is your source for this information? Did you email the company?

The only issue on my mind is the efficacy and safety of the combination treatment (their chosen protocol), obviously from a safety perspective it should be fine as it wouldnt have made it this far. And as for efficacy, well it has to be higher than the 70% which they quoted way back in 2012, perhaps we're looking at around 80% - 90% this time. Time will tell, but we can positively speculate that Aderans have performed what they wanted, which is the development of a superior protocol to take into phase 3.

[534623]

He is a doctor who has apparently cured hair loss, yet can't even manage to spell the word differentiation correctly.

And here is another such example …

Yep... and what did Follica do?...

Follica 2008: "cure will be available in 5 years time thanks to our research into mice wound healing".

Then we had retards laughing at Histogen saying "wnt ligands wont have ANY impact as the body will block them using wnt agonists".... *cough* *cough* Iron_Man rolf, too many shit-talking morons on these forums - the only company that has given results is the one people bash the most.

These morons can’t even manage to cite correctly. Just doctors can do this …

http://www.regenerativemedicine.net/images/PDF/hairfollicle.pdf

But Dr. Cotsarelis wrote in this paper (more or less between the lines on page 4, left column) the well-known (especially in UK) and famous sentence "... to date there has been no evidence that extracellular Wnt ligands can promote actual hair follicle neogenesis in adult skin" - what still remains correct. That's the reason why after 3 - 4 years (and beyond) after publication no working product is on the market.

[Alf]

All I want for Christmas is my two temples

[UK_]

Read the following back to yourself:

"Just doctors can do this …"

Your English is defunct.

534623 - I was paraphrasing an informal comment made on a separate website by someone who is actually probably you (Iron_Man).

The same person who 2 years ago said Histogen would have closed down by now because WNT proteins would have no impact on scalp hair growth.

Instead of going around picking faults in paraphrased comments, try learning how to rearrange a proper sentence in English in place of looking like a complete retard.

Have a nice day.