CB-03-01 - new antiandrogenic

[Swooping]

I posted this on another forum because people asked questions in relation to CB-03-01, many found it helpful so;

Does CB-03-01 work? Well it's a androgen receptor antagonist. Nobody reported results because nobody has a real clue on how to even approach things like pharmacokinetic properties of a drug.

The whole community reasoned that CB-03-01 didn't work because of vehicle issues. I knew immediately by having a look at the properties that it was a concentration issue. To no surprise obviously COSMO is trailing 2 x 5% a day now. There are no reasons to argue that there was ever a problem with the vehicle the as drug as it is low in MW and is of lipophilic nature.

Now your question is how well is CB-03-01 going to work? Based on the literature provided it seems to have the same activity towards the AR like cyproterone acetate which is a anti-androgen that is already on the market.

My speculative reasoning would be that it's going to be just about as good as finasteride in terms of results, perhaps a little worse.

The edge of CB-03-01 towards current treatments like finasteride *should be* by displaying a better side effect profile, not necessarily by providing better results. Eventually the real answer will come from their clinical trial results.

This is really true. For anyone thinking this will be the magical "thing", sorry CB-03-01 isn't going to be that. The effectiveness is probably going to be around the same as finasteride is, hopefully without the side effects. It will definitely not be better than something like dutasteride in terms of effectiveness.

Crown regrowth is cute but enough people show extremely good regrowth of the crown with finasteride (eventually coupled with minoxidil).

Sorry for being the "hope-crusher" again guys, but gotta stay objective here .

Nonetheless it will be still great if it does display a better side effect profile. Although somebody already showed me literature that the HTPA axis was altered in some subjects and I believe this is at a concentration of 1%. AFAIK they should be done with their data collection soon.

[Westonci]

I've been using cb now for about 5 months. I got it from the private forum and they have a custom liquid they made specifically for CB and I've had absolutely incredible regrowth in my crown.

I used to be a nw3 with a noticeable bald spot in the crown and now I have a FULL crown. I cannot believe it. After coming to this forum for so long I have finally beaten hair loss.

Holy shit dude, super exciting. Let us know what that custom liquid is!

Please Pm me or post it on reddit

https://www.reddit.com/r/tressless/

[dus]

I've been using cb now for about 5 months. I got it from the private forum and they have a custom liquid they made specifically for CB and I've had absolutely incredible regrowth in my crown.

I used to be a nw3 with a noticeable bald spot in the crown and now I have a FULL crown. I cannot believe it. After coming to this forum for so long I have finally beaten hair loss.

Congrats! Are there any plans on the forum on sharing information with the broader community?

[Soonbald]

isnt CB extremely expensive compared to RU? its like double the price..who can afford that? rich people? and I know which private forum you are talking about im a member there... but how much of CB do you need per day and how long does it last?? and how much did it cost like 300 bux?

[x4342]

I've been using cb now for about 5 months. I got it from the private forum and they have a custom liquid they made specifically for CB and I've had absolutely incredible regrowth in my crown.

I used to be a nw3 with a noticeable bald spot in the crown and now I have a FULL crown. I cannot believe it. After coming to this forum for so long I have finally beaten hair loss.

That's awesome to hear! You deserve it. I know you were struggling just a year ago.
Things are getting better. Even if the miraculous treatments don't materialize any time soon, it's nice to see that bridge treatments are becoming a reality.

[bananana]

I've been using cb now for about 5 months. I got it from the private forum and they have a custom liquid they made specifically for CB and I've had absolutely incredible regrowth in my crown.

I used to be a nw3 with a noticeable bald spot in the crown and now I have a FULL crown. I cannot believe it. After coming to this forum for so long I have finally beaten hair loss.

Pics or it didn't happen!

[FearTheLoss]

I've been using cb now for about 5 months. I got it from the private forum and they have a custom liquid they made specifically for CB and I've had absolutely incredible regrowth in my crown.

I used to be a nw3 with a noticeable bald spot in the crown and now I have a FULL crown. I cannot believe it. After coming to this forum for so long I have finally beaten hair loss.

[warner8]

would it be possible to buy a gram of CB through you?

I used seti for 2 months and it stopped shedding completely. Didn't have enough to use it can long enough to really judge efficacy. Then i started CB...it took about 4 and a half months before I started to see regrowth but i knew it was coming because I shed a bunch of hair. I started using 5% 2x a day in the custom liquid vehicle that the private forum sells. I don't know what the vehicle is made of, nor have I used CB in another vehicle but it's working for me so I'm pleased. Lately I've been using about 3.5%-4% 2x a day and it's still working well. I'm sure the quality vehicle has something to do with that.

SD I don't think the forum moderators here allow members to tell each other about other sites? hellouser is a member there though maybe he can help you get in.

I pay $150 a gram for CB.

[warner8]

is this the private forum that Swiss Temples mentioned in his blog, the one that practically no one can get into?

I am also interested to hear about your dose/regimen/side effects.

[Trouse5858]

I am also interested to hear about your dose/regimen/side effects.

+1. Minox is starting to lose efficacy and I'm simply running out of time

[CurlyBird]

I used seti for 2 months and it stopped shedding completely. Didn't have enough to use it long enough to really judge efficacy. Then i started CB...it took about 4 and a half months before I started to see regrowth but i knew it was coming because I shed a bunch of hair. I started using 5% 2x a day in the custom liquid vehicle that the private forum sells. I don't know what the vehicle is made of, nor have I used CB in another vehicle but it's working for me so I'm pleased. Lately I've been using about 3.5%-4% 2x a day and it's still working well. I'm sure the quality vehicle has something to do with that.

SD I don't think the forum moderators here allow members to tell each other about other sites? hellouser is a member there though maybe he can help you get in.

I pay $150 a gram for CB.

I am also interested to hear about your dose/regimen/side effects.

[sdsurfin]

I used seti for 2 months and it stopped shedding completely. Didn't have enough to use it long enough to really judge efficacy. Then i started CB...it took about 4 and a half months before I started to see regrowth but i knew it was coming because I shed a bunch of hair. I started using 5% 2x a day in the custom liquid vehicle that the private forum sells. I don't know what the vehicle is made of, nor have I used CB in another vehicle but it's working for me so I'm pleased. Lately I've been using about 3.5%-4% 2x a day and it's still working well. I'm sure the quality vehicle has something to do with that.

SD I don't think the forum moderators here allow members to tell each other about other sites? hellouser is a member there though maybe he can help you get in.

I pay $150 a gram for CB.

thanks FTL. How many grams do you use per month? Also, is there any way I can get in touch with you and buy it through you? I don't understand these private forums and such, I don't have so much time to waste on hairloss sites.

[FearTheLoss]

I used seti for 2 months and it stopped shedding completely. Didn't have enough to use it long enough to really judge efficacy. Then i started CB...it took about 4 and a half months before I started to see regrowth but i knew it was coming because I shed a bunch of hair. I started using 5% 2x a day in the custom liquid vehicle that the private forum sells. I don't know what the vehicle is made of, nor have I used CB in another vehicle but it's working for me so I'm pleased. Lately I've been using about 3.5%-4% 2x a day and it's still working well. I'm sure the quality vehicle has something to do with that.

SD I don't think the forum moderators here allow members to tell each other about other sites? hellouser is a member there though maybe he can help you get in.

I pay $150 a gram for CB.

[Paul73]

That's easily the most depressing part about hair loss. The science is here but the government red tape makes the products unobtainable in the near future. Oh no, there might be an unwanted side effect!! Don't worry though, finasteride only castrates you permanently and is FDA approved and you can still buy cigarettes and dip, cuz 'Mericaa!!!! Only five more years guys! ☹

Thanks to finasteride many of us still have hairs. Finasteride does not "castrates you permanently", don't exagerate. Persistent sexual side effects are rare.

Of course a treatment without sides is needed, i for example use fin for almost 20 years.

Só let's be patient, CB and other stuffs are close.

[Trouse5858]

also why is it taking CB so ****ing long to get to market? Is that what we can expect for SM and setipiprant too? Any scientists or docs on here can shed any light? 2021 seems crazy when they are wrapping up phase2, why does it take 6 more years to do a phase 3 and approval? SM is in the same spot pipline wise, will it take the same amount of time? In my opinion setipiprant is the most promising thing out there, and right now its looking like we wont get it until like 2025 based on how long CB is taking.

That's easily the most depressing part about hair loss. The science is here but the government red tape makes the products unobtainable in the near future. Oh no, there might be an unwanted side effect!! Don't worry though, finasteride only castrates you permanently and is FDA approved and you can still buy cigarettes and dip, cuz 'Mericaa!!!! Only five more years guys! ☹