Where are the phase IIb results for Bimatoprost?

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  • allTheGoodNamesAreTaken
    replied
    Originally posted by Occulus
    A protocol that resulted in 30% regrowth would be the biggest development since finasteride. It would be the biggest development of this generation. I would be ecstatic for something that resulted in a reliable 15% or even 10% regrowth, as there is nothing on the market that can produce that outcome. 10% regrowth would mean about 10,000 new hairs - something even a mega transplant session can't do.
    Don't those percentage of regrowth statements mean the percentage of what's left up there, rather than the percentage of hairs a person can possibly have on their head?

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  • BiqqieSmalls
    replied
    Originally posted by Occulus
    A protocol that resulted in 30% regrowth would be the biggest development since finasteride. It would be the biggest development of this generation. I would be ecstatic for something that resulted in a reliable 15% or even 10% regrowth, as there is nothing on the market that can produce that outcome. 10% regrowth would mean about 10,000 new hairs - something even a mega transplant session can't do.
    What's minoxidil's regrowth percentage?

    Leave a comment:


  • Keeper
    replied
    Originally posted by barfacan
    I really would like to see just how much of an effect lobbying has on the progression of hair loss treatments..
    I m sure Lobbying has a huge effect in this whole thing. Maybe they already have a cure, but its better for them to sell all crapy products.....makes more money

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  • Occulus
    replied
    Originally posted by rdawg
    And there are many companies working on the true cure, but it is a bit farther away than these 'mediocre' products that still are effective.

    if something is going to give me 30% regrowth+maintenance i'll definitely be lining up to buy, it doesn't fix everything, but i'd be happy enough with it and so would many others.
    A protocol that resulted in 30% regrowth would be the biggest development since finasteride. It would be the biggest development of this generation. I would be ecstatic for something that resulted in a reliable 15% or even 10% regrowth, as there is nothing on the market that can produce that outcome. 10% regrowth would mean about 10,000 new hairs - something even a mega transplant session can't do.

    Leave a comment:


  • barfacan
    replied
    I really would like to see just how much of an effect lobbying has on the progression of hair loss treatments..

    Leave a comment:


  • hellouser
    replied
    Originally posted by rdawg
    And there are many companies working on the true cure, but it is a bit farther away than these 'mediocre' products that still are effective.

    if something is going to give me 30% regrowth+maintenance i'll definitely be lining up to buy, it doesn't fix everything, but i'd be happy enough with it and so would many others.

    a true cure(NW7-NW0) is a much deeper problem, that judging by theories could be 5+ years away, so I dont understand why anyone would get mad if something comes out that isn't a complete cure.
    It was 5+ years 15 years ago. Aren't any of you tired of hearing this 5 year promise from doctors?

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  • rdawg
    replied
    Originally posted by BoSox
    Because it's almost 2016, and we should want/demand something better than mediocre.
    And there are many companies working on the true cure, but it is a bit farther away than these 'mediocre' products that still are effective.

    if something is going to give me 30% regrowth+maintenance i'll definitely be lining up to buy, it doesn't fix everything, but i'd be happy enough with it and so would many others.

    a true cure(NW7-NW0) is a much deeper problem, that judging by theories could be 5+ years away, so I dont understand why anyone would get mad if something comes out that isn't a complete cure.

    Leave a comment:


  • BoSox
    replied
    Originally posted by rdawg

    On a side note, interesting comments 2014, definitely still have faith in bim, not sure why anyone would upset with a minox on Roids, if it's good enough that you get some regrowth and it maintains+ you can drop fin/DUT it's a damn good upgrade to the current regime.
    Because it's almost 2016, and we should want/demand something better than mediocre.

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  • Dimoxynil
    replied
    Originally posted by TooMuchHairWontKillYou
    Sorry if it was asked but... If high % bim works on scalp why Chinese companies don't produce it?

    I have no faith in bim (
    Another angle on this for me is that these forums are mainly used by people from western countries. If the Chinese were developing something of their own it would take ages for the information to get across to us.

    Communication is everything

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  • Hairismylife
    replied
    Applying Pge2 directly is the same

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  • rdawg
    replied
    Originally posted by TooMuchHairWontKillYou
    Sorry if it was asked but... If high % bim works on scalp why Chinese companies don't produce it?

    I have no faith in bim (
    incredibly high cost, low demand(noone but a few rich forumers would be willing to get it) and the fact that it hasnt released results.

    On a side note, interesting comments 2014, definitely still have faith in bim, not sure why anyone would upset with a minox on Roids, if it's good enough that you get some regrowth and it maintains+ you can drop fin/DUT it's a damn good upgrade to the current regime.

    Leave a comment:


  • It's2014ComeOnAlready
    replied
    Originally posted by TooMuchHairWontKillYou
    Sorry if it was asked but... If high % bim works on scalp why Chinese companies don't produce it?
    Fair question - because the results have not been released yet. Nobody, besides Allergan knows if it works.

    The main deterrent for a Chinese lab or company is cost. Bimatoprost powder is very expensive ($800-900 per gram).They'd have to spend the time and money to make it without actually knowing it works, or the demand, because people like you and me don't know if it works better than minox. There aren't any actual numbers yet to go by.

    If they were to release results prematurely, they'd be creating a demand that only a lab or company not regulated by the FDA could get around.

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  • TooMuchHairWontKillYou
    replied
    Sorry if it was asked but... If high % bim works on scalp why Chinese companies don't produce it?

    I have no faith in bim (

    Leave a comment:


  • breakbot
    replied
    Originally posted by It's2014ComeOnAlready
    Said I wouldn't post until Nov, and I won't really because there won't be much news.

    Anyway, I'm posting today about Allergan's R&D key pipeline update taking place on November 4th which is in about two months.

    I am certain that at the very least, we will have results or news about the phase 2b trial. Since the merger, there was never any mention in any quarterly presentation (including when Actavis took over Allergan, and noted all of its pipeline products in a Nov. PDF, which excluded bimatoprost for scalp) of this drug in the pipeline or what its status was, and suddenly, it is featured among the late stage aesthetic programs a few months before a key R&D pipeline update.

    I think it's also important to note that this Q3 report and pipeline update is taking place at their Irvine, CA campus, former HQ of Allergan. Bimatoprost for hair growth was one of the late-stage pipeline programs that Actavis acquired from Allergan, and originated out of their Irvine HQ. When Actavis took over Allergan, their mid-to-late stage R&D programs were pretty thin as I have read.

    I have no idea if a product would be launched. I think it's possible given that they've really kept this a secret for nearly a year, and suddenly bim for scalp pops its head (of luscious hair) out, a few months before an R&D update. Not to mention that this R&D update is taking place from where this product originated. I've said before that given that this drug is already available, and would be in high demand if successful, they would not release results until they had a product to market. By withholding results, they have the power. People losing their hair are willing to slap almost anything on their heads to get their hair growing again. Believe it, if their product works (which all signs point to yes), and they released results prematurely, their potential profits would be poached by random labs, and chinese companies, and people would be eagerly slapping unregulated chemicals on their heads.

    On one hand I am certain that we will be made aware of the results of the this drug. On the other hand, I really have no idea if they will launch a product. What I also know is that it would be pretty lame and incompetent of them to say: "well, here are the results. As you can see, they are good enough to move forward with, and we plan on bringing this drug to market. We knew this drug worked nearly a year ago, but haven't jumped on it."

    I really can't see them (or any well-funded company) not taking action on this drug nearly a year ago if it worked. We all know that if the drug worked (which looks like a definite YES because they are moving forward with it) they'd try and push it to market ASAP. This is what any company with an effective drug for hair loss would do.

    ...And for anyone saying a phase 3 would never be initiated, or that it doesn't work - please use logic. They've named 70 mid-to -late stage drugs they are moving forward with. Bimatoprost for scalp is clearly marked as one of those drugs. "Moving forward" means continuing development, and after phase 2b comes phase 3. This is a company which states they do not like doing most of the R&D themselves because it is costly, and often doesn't produce results, therefore it is logical that if the drug failed in phase 2b, it would have been scrapped.

    Hold tight everyone, I'm certain November will be very positive.
    Omg! You destroyed allergan's plan!! You revealed them.
    Now everybody will buy bimatoprost!
    And of course allergan will publish their meaningless secret results.

    Leave a comment:


  • It's2014ComeOnAlready
    replied
    Originally posted by BoSox
    What are the expectations of this? Cure or just minox on roids?
    Minox on roids that can be used anywhere on the scalp - hairline, over the ears, crown etc.

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