follicept - what's this?

[BoSox]

I take back what I said 100%. I've been really down lately and had no excuse downgrading a potential product for all of us. Fact is they owe us nothing, so I should be thankful for anything that comes out. My apologies, and I'm usually the optimistic one.

Sorry fellas, and those working with Follicept as well. Looking forward to the new treatment.

[breakbot]

It's not the same. You can't inject something directly into a follicle. Injections go into the bloodstream. The point of this is to get very small doses very effectively into the hair chamber via the top of the skin.

It is the same. It has to damage a vein to get into the bloodstream. Think of bottox.
Think Histogen, Replicel. They are all working via injections.
Im out. Good luck to all of you and i hope i'm wrong.

[Hairismylife]

It is the same. It has to damage a vein to get into the bloodstream. Think of bottox.
Think Histogen, Relpicel. They are all working via injections.
Im out. Good luck to all of you and i hope i'm wrong.

May I have Devon to clarify this point?

[Jonathan]

You will never get the same spread with injections as you get with a gel that slowly penetrates the skin. If you made one tiny injection next to every follicle on the head maybe you would get close to the same effect, but it is practically impossible to inject such a small dose close to every hair follicle. On the scalp it is easy to spread it out over a big area, that is harder under the skin.

[Keki]

Clarify what? A no sense bullshit by someone who think that you have to damage a vein in order to reach the bloodstream? Can we please focus on igf-1 pubblications instead of answer every skeptical user? It's ok to be skeptical, just wait the end of the trial, devon answered the same questions OVER AND OVER AND OVER AND OVER, just stop and read the thread if interested it's annoying af

[Swooping]

Injections are still the best method for delivering large molecules. Although often invasive, they still can't be beat. Simple as that. If Devon or his research team argues otherwise then I would like to hear that, cause I will gladly get some experts in drug delivery to comment on this.

[breakbot]

Clarify what? A no sense bullshit by someone who think that you have to damage a vein in order to reach the bloodstream? Can we please focus on igf-1 pubblications instead of answer every skeptical user? It's ok to be skeptical, just wait the end of the trial, devon answered the same questions OVER AND OVER AND OVER AND OVER, just stop and read the thread if interested it's annoying af

Retarded, read again

[Clion1995]

They didn't fabricated the human trials

r u 3duc8ted?

[Keki]

Read again what, you and your toxic buddy can't even understand the different route of administration and the different effect and spread bullshit all over, and these questions have already been answered, if you don't have the time or interest to read the ****ig thread get out, NO ONE CARE, you arrogant trolls think they are some ****ig idiots that can't even understand how injection works and you want to teach them a chemical lesson about molecular weight, you can't even understand what he alredy said about that, what a joke, if you don't trust the product wait the trials and don't buy it, jeeee

[Swooping]

It's not the same. You can't inject something directly into a follicle. Injections go into the bloodstream. The point of this is to get very small doses very effectively into the hair chamber via the top of the skin.

Sdsurfin what are you talking about seriously? We are not talking about IV injections here. We are talking about delivering the compound in the dermis as a miniaturized hair follicles lies around ~2mm depth and a fully terminal around ~4mm. Besides that not everything that is delivered goes systemic. The pharmacokinetics of the compound are of utmost importance too, for instance the half life and metabolism of the compound.

Furthermore if you refer to "follicular delivery" by keeping the individual particle size under ~80nm then you are wrong too as the whole Topicon technology isn't based on that.

Besides that it doesn't matter anyway as injections are still the best whether it is delivered IV, IM, SUB-Q or in the dermis. The downside of it is that it is invasive. Breakbot is right. Devon knows this, his research team knows this. No way that they can disregard this.

[Jagger]

Sdsurfin what are you talking about seriously? We are not talking about IV injections here. We are talking about delivering the compound in the dermis as a miniaturized hair follicles lies around ~2mm depth and a fully terminal around ~4mm. Besides that not everything that is delivered goes systemic. The pharmacokinetics of the compound are of utmost importance too, for instance the half life and metabolism of the compound.

Furthermore if you refer to "follicular delivery" by keeping the individual particle size under ~80nm then you are wrong too as the whole Topicon technology isn't based on that.

Besides that it doesn't matter anyway as injections are still the best whether it is delivered IV, IM, SUB-Q or in the dermis. The downside of it is that it is invasive. Breakbot is right. Devon knows this, his research team knows this. No way that they can disregard this.

Jesus man, you're like, the king of ad hominem. Just make your argument, personal attacks lessen your credibility.

[Swooping]

Jesus man, you're like, the king of ad hominem. Just make your argument, personal attacks lessen your credibility.

Mmm. Only with guys who spew out bullshit and subsequently attack other people for making valid points. But you are right, I'll keep it on a lower level .

[breakbot]

r u 3duc8ted?

I'm sorry. My mistake, Clown 1995.

[follicept]

Do you have an estimated date for releasing the results from the 2-4 week human trials?

You'll be releasing those results before the indiegogo correct?

I'd have to imagine if the human trials go that well, you should be able to find a partner to get that igf-1. I can't imagine somebody holding the key to a multi-billion dollar baldness cure and not being able to find a partner who can mass produce igf-1 as needed.

2-4 weeks after they start, haha. Basically, going to try on myself and a few others as a convenience sample, just before or same time as randomized trials start. If enough of us start to see good growth, and/or the trials are progressing such that we're confident in the product (even if we don't have full, published results) we will probably launch. Yeah, there are others who can make it but don't currently. The indiegogo would help us raise the funds to get them to start manufacturing asap.

[follicept]

I take back what I said 100%. I've been really down lately and had no excuse downgrading a potential product for all of us. Fact is they owe us nothing, so I should be thankful for anything that comes out. My apologies, and I'm usually the optimistic one.

Sorry fellas, and those working with Follicept as well. Looking forward to the new treatment.

No worries. Thanks for the apology, it takes a lot and means a lot. Trust me, I am there too. You have no idea.