Final Days: Chinese Scientists Have Solved the DP Culturing Problem! (2014)

[hellouser]

I hope the European Medicines Agency works faster than the FDA.

How does the process compare to the likes of Japan, China even India?

Good points guys! We need to figure out what can be done to get this treatment out the door as fast as possible and put us out of our misery! I dont care where I have to travel in the world to get this.

Whichever country releases it first will see a nice revenue stream, remember:

Money > Empathy

[garethbale]

Good points guys! We need to figure out what can be done to get this treatment out the door as fast as possible and put us out of our misery! I dont care where I have to travel in the world to get this.

Whichever country releases it first will see a nice revenue stream, remember:

Money > Empathy

What about Somalia, North Korea or Syria?

[hellouser]

Just had a discussion with another forum member on ***, this is particularly interesting:

If I understand the first post correctly, they've come up with a way to clone hair. Why would it take 5 years? Why can't they transplant that hair right away? If it isn't a drug why would it need to be tested for safety? Transplanting hair is already established as being safe.

Why couldn't a hair transplant surgeon fly there tomorrow with a sample of your hair, come back with you when just 5 days later when it's finished cloning and transplant it on your head?

I agree somewhat but I would still want AT LEAST one safety trial followed by a second larger safety trial. If the treatment works, it will be known RIGHT AWAY from the first safety trial as the results will be stupidly obvious; either hair is there or not! I wouldn't want to transplant follicles that contain anything dangerous and risk something far greater than hair loss/social rejection.

I really don't think efficacy trials will be needed... that should be easily determined from a single safety trial.

I see what youre sayign though! If they're already follicles, what is so different from them coming from a donor area via traditional hair transplant. It's not like we're injecting pure stem cells that MAY turn into something else. These would be fully functioning and COMPLETED organoids, ie; follicles.

So that being said; if the cells turn into follicles... what's the point of going through so many trials?

[Number47]

Thats great news lets hope something good comes out!

on a side note...guys i have been in these forums for years and i have never seen a character like iron man before lol. The guy is hilariously psychotic. Thank god there are posters like Arashi in here or his scientifically dressed BS would confuse people!

[lurker77]

Thats great news lets hope something good comes out!

on a side note...guys i have been in these forums for years and i have never seen a character like iron man before lol. The guy is hilariously psychotic. Thank god there are posters like Arashi in here or his scientifically dressed BS would confuse people!

Not just THESE forums, but any forums on any topic. People like him are a rare breed. Obsessed, delusional, and deranged. At a certain point I stopped being irritated and started just feeling bad for the guy.

[534623]

Face it IM these asian guys are killing the game right now, way more intelligent, capable and dedicated compared to most euro/NA researchers

Not really. Oh, and why I called all this "trash science":

European researchers did this ...

To show the DP cells didnt lose their follicle inducing ability (like normally happens when culturing DP cells), they even induced some hair like fibers. But all in a dish !! This is TOTALLY different than growing REAL hair (like Tsuji did) on skin. This doesnt somehow show the Chinese failed (like you make it look) at all.

...while I, IN FACT, said this concerning the latter part (ADHD is still a big problem these days lol) ...

The Chinese scientists "failed" insofar (it wasn't their intention to produce with this approach fully functional hair follicles) and produced just "hair-like fibers", because their source lacked the proper instructions ...

...already in 2005:

"Reorganization of hair follicles in human skin organ culture induced by cultured human follicle-derived cells" - "Experimental Dermatology" (Bd. 14, S. 580; August 2005)

So they didn't just produce "hair-like fibers" in a petri dish (again, it wasn't the intention of the Chinese scientists to produce fully functional hair follicles, as already mentioned!!), they even produced real growing and functional "VELLUS-LIKE HAIR" in a petri dish. And to accomplish the latter, of course, they could also already retain the DP cells (and others) HF inducing capability (otherwise no hair at all!) - in 2005!

btw - Even the title of the European scientists paper is pretty similar to the papers' title from the Tsuij lab scientists:
It's all about "how-to" REORGANIZE/RECONSTRUCT hair follicles; the European scientists did it simply in vitro (in a petri dish) and the Tsuij lab guys did a simlar approach finally in vivo (after some pre-culturing in vitro); in this case in a mouse to produce at least "a" wispy hair.

Furthermore, the ADHD-guy is still thinking that using INTACT dermal papilla's (or plural "papillae") is completely the same thing than using just CELLS of intact dermal papilla's ...lol

On the other hand, it doesn't matter anyhow, because many don't even know what "reconstruction" or "reorganization" of something actually means ...lol

Anyway, now almost 10 years later (after publication of the European paper, for example), I always find it amusing when some baldies get excited when some "scientists" on this planet create some hairs in a petri dish - or "a" wispy hair on a mouse's back.... and start "the final cure is near" trash.

[tonypizza]

I really believe if a blueprint for a cure is found, things will progress much faster than anyone would expect. The first country to offer this treatment would see a ton of investment from drug companies looking to be auxillary as part of the regimen, to hair clinics looking to legally offer the treatment. Universities will boom with research grants looking into production and packaging of the product. Medical tourism will skyrocket.

[hellouser]

Anyway, now almost 10 years later (after publication of the European paper, for example), I always find it amusing when some baldies get excited when some "scientists" on this planet create some hairs in a petri dish - or "a" wispy hair on a mouse's back.... and start "the final cure is near" trash.

If these are some 'scientists' what does that make 'Dr. Gho' ??

[Atum]

I really believe if a blueprint for a cure is found, things will progress much faster than anyone would expect. The first country to offer this treatment would see a ton of investment from drug companies looking to be auxillary as part of the regimen, to hair clinics looking to legally offer the treatment. Universities will boom with research grants looking into production and packaging of the product. Medical tourism will skyrocket.

Indeed, if this get's released in china in 1 or 2 years time, i better start learning chinees, cause I will be there.

[ytterligare]

why? I'm speaking Swedish, English and German that has to be enough Better THEY brace themselves, because baldies from abroad are coming. Actually you'll only need to put your finger on the spots where you want more hair

[534623]

why? I'm speaking Swedish, English and German that has to be enough Better THEY brace themselves, because baldies from abroad are coming.

Actually you'll only need to put your finger on the spots where you want more hair

Right - as they said this in 2005/2006 already (actually since decades). But I think you (and most other guys here)
will rather end-up like the guy in the bottom right corner in this article ...

[Jazz1]

All I can say is the western world especially Uk most guys shave it and don't give a fu*k. The Chinese however take pride in their appearance, nice skin, features and especially hair. Chinese are know for their beautifull hair and skin, but these days somehow they are balding, blaming the western diet etc. I reckon they care more about their hair than any western country, hence why I can see them being more desperate for a cure.

[hellouser]

All I can say is the western world especially Uk most guys shave it and don't give a fu*k. The Chinese however take pride in their appearance, nice skin, features and especially hair. Chinese are know for their beautifull hair and skin, but these days somehow they are balding, blaming the western diet etc. I reckon they care more about their hair than any western country, hence why I can see them being more desperate for a cure.

Good, the faster they come out with a commercial product, the faster we can fly our bald heads to china and dump some serious cash into their economy.

I'll stay longer and do some touring while im there too, so they'd kill two birds with one stone.

[DesperateOne]

The trials really shouldn't take that long as well, which is a good thing. There is no placebo test or anything. I would like it to be a trial with people with different color hair, see how they respond. Transplant the hair and in 4 months, bam, hair retries all nice. The only problem I can see is the so called hairloss shock after a transplant.

[nameless]

Well keep in mind that:
1) Tsuji labs already proved that this is the last step
2) Jahoda grew hair on human skin, but his method needed improvement to retain gene expression
3) These Chinese solved that last part.
4) That Taiwanese group is starting clinical trails with 3d cultured DP cells NOW, you can bet that they take info like this into account.

So the future does look bright. Very bright indeed !

Arishi, I see where you're going with Items 1 - 4 and I hope you're right that the Taiwanese group takes this new info into account. And how do you think this new info will play in combination with the other recent information coming out of the University of Pennsylvania team with Cotseralis? Here is that information:

http://www.sciencecodex.com/converting_adult_human_cells_to_hairfolliclegenerating_stem_cells-126870

Does all this information combined equal a cure for hair loss and are the Taiwanese paying attention to this new information? If they aren't noticing this new information perhaps it would be a good if we informed them about all of these new recent events so they could incorporate all of the new information into their studies?????