Histogen at the ISHRS conference

[rdawg]

i saw a youtube video with someone commenting that histogen isnt that effective at all. he said the numbers look good on paper. but the pics show something quite different. i dont mean to be a bad news breaker. heres the link:

https://www.youtube.com/watch?v=khVm4wSpzjo

A: this is two months old.
B: there were alot of skeptics, Histogen only had 15 minutes to present and a few minutes for questions.
C: The two photos/people he showed had clear growth, those were the best ones, you'd have to be blind not to see at least slight growth there.

Yes some of the photos were underwhelming, but they were at the early stages anyway, many were only at the 4-6 month range after receiving the HSC.

fine to be a skeptic, he's not even being that negative, just saying wait for better pictures, so its not bad news at all.

[kanyon]

Great reply UK Boy, that's the problem with some members in the forum. Histogen is a product ready to be used on you via injections. I believe our main goal is to get some hair and not chit chat. Racism gets nasty over here as they always look at Asians in a lower gaze where they might over take the west with their developments one day.

I didn't mean to sound racist. I'm far from racist.

I could get 6 weeks off work for repeat injections. Is the period in between dehabilitating? If not, I would use the time to travel around

When we walk about Asia, are we saying Japan, Singapore, Thailand? Or do you think it will be released everywhere? Do Europe and Australia rely on FDA?

[HARIRI]

Kanyon, I think most likely it will be released in Singapore. I'm sure Rdawg may have some information about it as he closely following it.

[Pate]

Interesting, I know ziering is in the states, like california area. Then the main doctor is doing it somewhere in asia.

so isnt Ziering doing tests through the FDA in North America?

Ziering's trial isn't part of the Phase II, it's a "physician-sponsored trial" to support Histogen's IND application to the FDA. So it's like a pre-trial so they can get FDA approval down the track.

The Phase I trial was in Honduras and the Phase II is in the Philippines. Like I said these are done to full FDA specifications so they can be submitted to the FDA.

[Pate]

Can you tell me more about RU? Why aren't more people talking about it/ using it then? And why doesn't the doctor prescribe it?

Because the company that owns the patent is sitting on it and not pursuing it, so nobody can get it legally as a hair loss product.

Nobody knows 100% for sure whey they are sitting on it, but it's probably some or all of:

1. Very powerful topical anti-androgen with the potential for systemic absorption which may lead to pregnancy defects (a pregnant woman running her hand through your hair would be a potential risk)

2. It's unstable, breaks down in a few weeks at room temperature, so it's not good for a hair loss product (you can't sit it on the shelves)

3. It's more effective than fin but still won't grow significant amounts of new hair (ie it's not a hair loss cure, more preventative treatment like fin)

4. The combination of the three points above mean they can't find an investor willing to spend the half-billion dollars or so it would cost to get it tested and approved

5. Because of that it's been so long since the patents were taken out that the patents will soon expire, so the financial return on investment isn't worth it.

Histogen is actually making this worse too. HM in general is a big risk to any hair loss drugs. They cost so much money to develop that nobody wants to fork out the money if HM is going to render it obsolete.

So I don't think you will ever see RU available in stores. Once the patents expire it's all over, nobody will develop RU when they can't even get their R&D costs back.

On the plus side, if Histogen does work, those of us using RU should theoretically be able to use it to protect our new Histogen hair from DHT.

[koolx]

A: this is two months old.

so?

B: there were alot of skeptics, Histogen only had 15 minutes to present and a few minutes for questions.

so?

C: The two photos/people he showed had clear growth, those were the best ones, you'd have to be blind not to see at least slight growth there.

not really. the growth was noticeable but not impressive.

Yes some of the photos were underwhelming, but they were at the early stages anyway, many were only at the 4-6 month range after receiving the HSC.

stop fooling yourself.. saying that theyre in the 'early stages' is just an excuse.. the company had enough time to prepare this med.

fine to be a skeptic, he's not even being that negative, just saying wait for better pictures, so its not bad news at all.

no, hes saying dont get your hopes up.

[hellouser]

stop fooling yourself.. saying that theyre in the 'early stages' is just an excuse.. the company had enough time to prepare this med.

Sounds like youre well informed about the preparation of the med. Can you tell us why it wouldnt need to take as long as it did?

[koolx]

Sounds like youre well informed about the preparation of the med. Can you tell us why it wouldnt need to take as long as it did?

sounds like ur the spokesperson for the company. can you tell us why your company fails to provide a better product?

[hellouser]

sounds like ur the spokesperson for the company. can you tell us why your company fails to provide a better product?

Dodging the question tells me and everyone else on this forum you know f*ck all about the meds and why it would take any length of time that it could and did.

Should have manned up and admitted that you simply don't know rather than trying to post your disappointment as a fact only to help your own OPINIONS. Stick to being objective and realistic rather than another useless pessimist on the forum, nobody needs your negativity as it adds NOTHING to the forum.

If youre going to be a pissy crybaby, at least state what your intentions are.

[rdawg]

so?
so?

not really. the growth was noticeable but not impressive.

stop fooling yourself.. saying that theyre in the 'early stages' is just an excuse.. the company had enough time to prepare this med.


no, hes saying dont get your hopes up.

lmao, how is noticeable growth NOT impressive? And this is only after a few months.

early stages goes for any medication AND hair transplantation, everything has to go through hair cycles, which can take time. Why are you saying that a medication can skip over hair cycles? This is also without mentioning that it takes time to change the system and for the hair follicles to accept the medication etc.(this goes for anything, I.e Finasteride which can take up to a year to affect some people).

Ok if he's saying dont get you're hopes up, nowhere does he say it doesn't work.

Quit looking for something to be negative about. They've shown 'noticeable but unimpressive' growth, which is growth, period. So I dont see the problem you have here.

EDIT: In fairness noone has claimed this to be the cure, but wait for the results this year as many will be in their second year of results and many will have had more frequent injections(as well as a larger area) in an attempt to get even more growth. I think most if not all of these early patients only had a small area injected.

[mjolnir]

sounds like ur the spokesperson for the company. can you tell us why your company fails to provide a better product?

Because regenerating human organs is hard? We can't regrow eyes, hearts, teeth, etc., so why is it surprising that companies might have a little trouble regrowing hair?

[koolx]

Dodging the question tells me and everyone else on this forum you know f*ck all about the meds and why it would take any length of time that it could and did.

Should have manned up and admitted that you simply don't know rather than trying to post your disappointment as a fact only to help your own OPINIONS. Stick to being objective and realistic rather than another useless pessimist on the forum, nobody needs your negativity as it adds NOTHING to the forum.

If youre going to be a pissy crybaby, at least state what your intentions are.

fearing answering my question tells all of us here that u know d'ick about the med the company is paying u to rep. stick to ur day job since u dont cut it as a real man with the testicles to tell the truth, but just a little internet p'ssy. nobody needs ur lies as it does nothing but inflate false hope.

u shouldve been a real man with balls and not bi-male about telling the truth about this product u know SH'IT about so ur company can fool people into buying it.

if ur gonna be an unmanly mule for the company, at least admit it so ur parents can know they didnt give birth to a girl.

lmao, how is noticeable growth NOT impressive? And this is only after a few months.

cuz its not enough.

early stages goes for any medication AND hair transplantation, everything has to go through hair cycles, which can take time. Finasteride which can take up to a year to affect some people).

then why didnt they provided a model showing the full length of the hair cycle instead of an "incomplete" one?

Ok if he's saying dont get you're hopes up, nowhere does he say it doesn't work.

i never said nor did i say he said that it doesnt work. it just doesnt work as well as expected.

Quit looking for something to be negative about. They've shown 'noticeable but unimpressive' growth, which is growth, period. So I dont see the problem you have here.

i'm not.. i'm stating an observation. if my observation is negative to u, then ur the one spinning it negatively. the growth isnt impressive. if u dont see that prob, then ur only fooling urself.

EDIT: In fairness noone has claimed this to be the cure, but wait for the results this year as many will be in their second year of results and many will have had more frequent injections(as well as a larger area) in an attempt to get even more growth.

i agree but disagree too. ur right, no one claimed this to be a cure. but its been spinned like it is. this is why my expectations shot thru the roof until i saw the youtube and the pics.

I think most if not all of these early patients only had a small area injected.

u think? how do u know this? i think the world will end tmrw.. will it?

Because regenerating human organs is hard? We can't regrow eyes, hearts, teeth, etc., so why is it surprising that companies might have a little trouble regrowing hair?

not fully.. but currently thru stem cells we can regrow parts of limbs, parts of eyes, and parts of organs in both animal and human models. the tech is limited now. but in the future its expected that the tech will make this transition to full organs.

[Desmond84]

so?



so?



not really. the growth was noticeable but not impressive.



stop fooling yourself.. saying that theyre in the 'early stages' is just an excuse.. the company had enough time to prepare this med.



no, hes saying dont get your hopes up.

Hey guys,

First of all, merry xmas to all my balding brothers wishing u all the very best.

Secondly, koolx I've attached a copy of the trial in the link below for you to look at. I think your confusion comes from the fact that you're not aware of the number of injections they used. This was merely a safety trial (Phase I/IIa). So they only injected each patient with 8 injections at 3mm apart. Now, in order for you to notice significant cosmetic growth on the top of your scalp, they need to inject 200-300 injections!

Now I promise you they will eventually reach a point where they will inject the whole scalp (Phase IIb) and by the look of things, the results will be impressive. Just be patient and don't attack anyone on the forum! We're all here to help each other get through this curse

Peach brother

http://clinicaltrials.gov/ct2/show/NCT01501617?term=histogen&rank=1

[Kiwi]

Hey koolx...

... This is where I tell you to f*** off and die like all the other sceptics and whiney little bitches.

As punishment I hope that when Histogen does come out and does work that people like you wont be able to afford it.

[Kiwi]

And to everybody else.... Merry Xmas!!!

May Histogen / Aderans blow our socks of in 2013!!!

Ciao,
Kiwi