Histogen at the ISHRS conference

[2020]

It's all about growth factors my balding brothers. If Histogen was going HAM with their injections (aka higher dose/frequency) AND using an AA, believe me results would be legit. Growth factors are thee big pieces of the puzzle.

why don't they just do that then? How smart would it be to actually inject as much as humanly possible on ONE person and see if it produces good results. Then they could see if HSC is worth pursuing instead of now wasting decades without knowing how will it turn out... they're just wasting investors money and investors wouldn't necessarily panic over that since almost 90% of companies like Histogen fail. It's commonly known so. Look at initial returns of YouTube and Facebook versus starting investment. It's certainly more than 10x. It's all go big or nothing...

[koolx]

The Phase II trial began in January 2012 so the 12 month results should be out in 3 months time or around then. I don't know when Ziering's trial began. Probably about the same time.

The micro photos of the buzzed hair were at 12 weeks.

The macro photos of Ziering's trials were 12 weeks, 19 weeks and 24 weeks from the first set of injections.

Ziering's trials had up to four sets of injections at 0, 6, 12 and 18 weeks. Leave them for 12 months and then have a look at the macro photos. If they don't have significant cosmetic hair growth by then, then the critics will be right.

12 weeks? Sounds good.. So lets see what the results will look like after 12 months. Hopefully in 3 months when the results are released that the pics will look as good as expected. I hope I'm wrong about my pessimism.. But I'm not gonna hold my breath.

[rdawg]

The Phase II trial began in January 2012 so the 12 month results should be out in 3 months time or around then. I don't know when Ziering's trial began. Probably about the same time.

The micro photos of the buzzed hair were at 12 weeks.

The macro photos of Ziering's trials were 12 weeks, 19 weeks and 24 weeks from the first set of injections.

Ziering's trials had up to four sets of injections at 0, 6, 12 and 18 weeks. Leave them for 12 months and then have a look at the macro photos. If they don't have significant cosmetic hair growth by then, then the critics will be right.

It was gail's trial that started in January I believe.

Zierings was around may/june for some of the patients(not sure when he first started, but he mentioned a couple new patients coming in in june). That's why some pictures were from very early in the process for a few patients, as in 6-10 weeks for a couple of them.

They definitely need more time before we can make an absolute judgement about anything, so a year is usually common.

The early results have been great IMO, we'll see what happens with full year for multiple patients though(and more doses in phase IIb).

[mjolnir]

this thread is such a rollercoaster between soon having a cure and to everything is hopeless. As far I'm concerned, Aderans and Replicel are finished. Don't expect anything from them. They don't have anything now nor will they have anything in the future.
desmond was right when he said that those were our only hopes in the next 10+ years. Take away those two, and you're only left with Histogen who has shown poor results at this point however you want to spin it. They had more than 5 years to figure out this crap and up to this point they got nothing.

What the heck are you talking about? Both Histogen and Aderans have photos showing visible growth, and so long as no serious health concerns arise, they'll both probably make it to market.

[hellouser]

What the heck are you talking about? Both Histogen and Aderans have photos showing visible growth, and so long as no serious health concerns arise, they'll both probably make it to market.

Ignore him, hes a fool, he'd like you to believe that 200 million dollar acquisition Aderans made on Bosley means the company is going to tank..... NOT that it will use bosley clinics as a vehicle for their final product.

[koolx]

this thread is such a rollercoaster between soon having a cure and to everything is hopeless.
you're only left with Histogen who has shown poor results at this point however you want to spin it. They had more than 5 years to figure out this crap and up to this point they got nothing..

i got to agree.. theres been so much talk about these "cures" over the yrs that its gotten sick already. the pics from histogen are really discouraging.

but can someone please post links of pics of hair restoration of Aderans and Replicel? i'd appreciate it.

[534623]

What the heck are you talking about?
Both Histogen and Aderans have photos showing visible growth ...

What the heck are you talking about??
Could you please post these PHOTOS where you can see "visible growth"?

[rdawg]

What the heck are you talking about??
Could you please post these PHOTOS where you can see "visible growth"?

I dont know how anyone can say there isnt a reversal of vellus hairs there. Slightly different lighting but you can clearly tell the first pictures had miniaturized hair that was white and was not growing at all, then she essentially grew numerous hairs on her temple. This was only after 19 weeks as well which is less than 5 months. Noone was beyond 24 weeks in the process from what I read, the most dosage I saw was 40 injections, but they did not state which area was injected.

I reiterate AGAIN, that this women ONLY received 20 injections.(repeated twice I may add though). So the fact that youre seeing reversal of vellus hairs is fantastic with this few injections at only 19 weeks! Numer

The other pictures also early in progress, showed minor growth as well, but the lighting was tricky so it's hard to definitively get behind them. None of the pictures seemed to show less hair, IMO they all showed varying degrees of growth and reinforcement(again it's debatable though as histogen needs to work on their pictures.)

I think they're just gonna wait until feb/march so they can see if they can get even better pictures, maybe they realized the ones they had would just get argued over with the difference in lighting etc.

[koolx]

I dont know how anyone can say there isnt a reversal of vellus hairs there. This was only after 19 weeks as well which is less than 5 months. Noone was beyond 24 weeks in the process from what I read, the most dosage I saw was 40 injections, but they did not state which area was injected.

I reiterate AGAIN, that this women ONLY received 20 injections.(repeated twice I may add though). So the fact that youre seeing reversal of vellus hairs is fantastic with this few injections at only 19 weeks!

I think they're just gonna wait until feb/march so they can see if they can get even better pictures, maybe they realized the ones they had would just get argued over with the difference in lighting etc.

ok, the pics look good. now lets see the year long trial pics come feb or mar. that will be the true test.

but this is just one patient whose pic youve shown. just be weary. many times companies trial 100 patients but showcase only a few patients that they feel have the best results. so, out of 100 if 3 showed the best results, theyll show that. but they wont show the 97 patients that lacked the results they anticipated. i'm not trying to be an ass. but i dont want ppl to be fooled out there either.

[rdawg]

ok, the pics look good. now lets see the year long trial pics come feb or mar. that will be the true test.

but this is just one patient whose pic youve shown. just be weary. many times companies trial 100 patients but showcase only a few patients that they feel have the best results. so, out of 100 if 3 showed the best results, theyll show that. but they wont show the 97 patients that lacked the results they anticipated. i'm not trying to be an ass. but i dont want ppl to be fooled out there either.

I agree with you 100%, all I'm trying to say is exactly what you just said, wait for the next results, but the early results were promising.

Histogen needs to show MORE for sure, but I'll give them time to improve their results/wait for the results to get even better before I put a full judgement on them.

I'm very optimistic about them, they need to improve their pictures, but with them adding more injections in the next phase, not only will the feb/march update be big(full results for IIa) but the october next year will huge, as that's where the most injections would have been done and all patients would have been on this stuff for a while.

[jman91]

bump 10 charrrrrrrrrrrrrrrrr

[jackhammer199]

Wow, those pictures look INCREDIBLE...if they are in fact accurate and reliable? I hadnt seen any pictures from Histogen that looked anything like it, only the bird's eye view of a middle aged man's wispy hairs looking vaguely longer after a course of treatment...nothing as substantial and as thick as the pictures a few posts above me!!!!!!

This is good news, no??!!

[koolx]

Wow, those pictures look INCREDIBLE...if they are in fact accurate and reliable? I hadnt seen any pictures from Histogen that looked anything like it, only the bird's eye view of a middle aged man's wispy hairs looking vaguely longer after a course of treatment...nothing as substantial and as thick as the pictures a few posts above me!!!!!!

This is good news, no??!!

its only a good as a reliable mean sample. if a majority of trial patients regrow hair this dense then i'd be optimistic. but if only 1 or 2 ppl out of 100 show this much hair then i wouldnt trust it at all. in that case its a shot in the dark chance.

[jackhammer199]

Yeah, I guess we're playing the waiting game then...so desperate for this to work, i am rapidly receding into severe NW3 territory..i might even be there already and i'm just deluding myself.

COME ON HISTOGEN!!!!!!!!!!!!!!!

[534623]

...nothing as substantial and as thick as the pictures a few posts above me!!!!!!

This is good news, no??!!

No, in fact, not at all, but such photos are at least sufficiently good to prevent a too high rate of hair loss suicide victims.