CB-03-01 - new antiandrogenic

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  • Tenma
    replied
    Originally posted by doke
    An article by john ertel at regrowth com many years ago stated that ru58841 was the mother of all antiandrogens and without side effects and its as strong as flutamide and stronger than finasteride but topical application.
    So is it stronger than cb 01 03 it maybe?

    I think CB is a bit stronger, but cant tell you for sure. There is one paper discussing the antiandrogenic activity of the drug. if someone can find it that would be great.

    Here is the abstract of the study we need to read:

    The aim of this study was to investigate the antiandrogenic activity of a new monoester of cortexolone, cortexolone 17alpha-propionate (CAS 19608-29-8, CB-03-01). Although the compound displayed a strong local antiandrogenic activity in hamster's flank organ test, it did not exhibit antiandrogenic a …

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  • simba
    replied
    Originally posted by burtandernie
    Too early to say. Contrary to what many others on here think CB 03 01 is an entirely experimental chemical that is not close to fully studied. Its anyone guess what it could do or how well it works. In theory its a powerful AA with a small preliminary study they did showing it works twice as well as propecia.
    I dont want to wait 3 or 4 years, but using it now is questionable at best and not indicative of any possible results when it eventually does come out. Its not out yet to buy because of many good reasons
    The chemicals CB-03-01 degrades into are well known to be safe.

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  • doke
    replied
    An article by john ertel at regrowth com many years ago stated that ru58841 was the mother of all antiandrogens and without side effects and its as strong as flutamide and stronger than finasteride but topical application.
    So is it stronger than cb 01 03 it maybe?

    Leave a comment:


  • burtandernie
    replied
    Originally posted by WashedOut
    Is CB the real deal when it comes to stopping future loss? It would be a shame to wait 4 years to see it's not much more effective than other stuff we have now.
    Too early to say. Contrary to what many others on here think CB 03 01 is an entirely experimental chemical that is not close to fully studied. Its anyone guess what it could do or how well it works. In theory its a powerful AA with a small preliminary study they did showing it works twice as well as propecia.
    I dont want to wait 3 or 4 years, but using it now is questionable at best and not indicative of any possible results when it eventually does come out. Its not out yet to buy because of many good reasons

    Leave a comment:


  • doke
    replied
    Originally posted by kobefan234
    doke- yes the smell is terrible with liquid spiro. i also have the cream although i don't know if its working or not.

    i apply it to the temple areas.

    not much smell to ru58841 which is good and its better than spiro.

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  • kobefan234
    replied
    doke- yes the smell is terrible with liquid spiro. i also have the cream although i don't know if its working or not.

    i apply it to the temple areas.

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  • doke
    replied
    Originally posted by kobefan234
    do you use this product ?

    hi i do not use the liquid spiro although i do still have the one in your picture but it smelt too strong so i used the cream instead which also has caffein in.
    I stopped spiro now and am on 5% ru premix from anagen which has no smell and once a day at night 2mls of minox.

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  • WashedOut
    replied
    Is CB the real deal when it comes to stopping future loss? It would be a shame to wait 4 years to see it's not much more effective than other stuff we have now.

    Leave a comment:


  • burtandernie
    replied
    Originally posted by lilpauly
    Who says propecia doesnt work on front ? Who says Minox doesn't work on hairlines? I suggest u look at the studies again it was NEVER tested on the hairlines . Also all the information you are asking has been presented in countless Cosmo presentations
    Propecia does have studies on the front showing it works, but it doesnt work as well there as it does in other places. Many men still get mature hairlines even on propecia or get some slight recession over many years on propecia. So why that difference or why do some men continue losing hair even on propecia when it doesnt work? CB might have answers there.
    There are more studies to be done on CB or it would be approved already it seems.

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  • kobefan234
    replied
    Originally posted by doke
    spiro 5% cream has never caused me any problems oral may but its been out a long time for acne as well.
    do you use this product ?

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  • lilpauly
    replied
    Originally posted by burtandernie
    Im curious to just see some studies or results on CB long term how it does in terms of preventing or stopping MPB or maybe how it does in the front verses the crap we have now where even propecia fails at the front. Is the sensitivity at the front and temples like a mature hairline from T or the DHT left over from propecia? CB might provide the answers.
    Who says propecia doesnt work on front ? Who says Minox doesn't work on hairlines? I suggest u look at the studies again it was NEVER tested on the hairlines . Also all the information you are asking has been presented in countless Cosmo presentations

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  • burtandernie
    replied
    Im curious to just see some studies or results on CB long term how it does in terms of preventing or stopping MPB or maybe how it does in the front verses the crap we have now where even propecia fails at the front. Is the sensitivity at the front and temples like a mature hairline from T or the DHT left over from propecia? CB might provide the answers. If its side free and ends up working well and gets finished its a dream product for sure at least as big as propecia was.

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  • simba
    replied
    Originally posted by efedrez
    I'm considering RU since fin is giving me sides but since your are mentioning that RU can give you the same sides, I'm curious about why did you decided to go with RU, which is still an experimental drug and much more complicated to mix than simply taking fin
    Using fin at 0.25mg ed killed my penis within 10 days (went totally back to normal 3-4 days after stopping).

    Ive been at 1ml RU @5% ed for 3 months now (and one year of minox) with decent results and no sides at all. I really need to make a log of it.

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  • doke
    replied
    Originally posted by Mike K
    Any chance you could tell me where I could find this thread? I know that we can't post links but maybe which site and what user it was so I can go there and search? I'd like to see it if possible.


    That's a lot of stuff. Do you have any pics of your progress? Also, where do you get 15% minox? Dr. Klein?


    This is what is stopping me from adding spiro topical or oral. I'm all for lowering DHT but I don't like the idea of lowering test entirely. Plus I heard it smells bad.
    hi i use dualgen 15% sensitive formula.

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  • Mike K
    replied
    Originally posted by strife91
    i believe wounding works but needs to be done properly , i have seen a dermarolling thread with amazing results no minox or anything. he went all out though
    Any chance you could tell me where I could find this thread? I know that we can't post links but maybe which site and what user it was so I can go there and search? I'd like to see it if possible.
    Originally posted by doke
    We do not know whether cb is any better than spiro cream 5% as i use this alongside kanes ru premade and minoxidil 15% and getting regrowth forgot to mention the igrow which i will not be without.
    That's a lot of stuff. Do you have any pics of your progress? Also, where do you get 15% minox? Dr. Klein?
    Originally posted by HairBane
    most of us do not use spiro because we dont want to turn into women cb is supposed to have no side effects yet be as effective if not more effective than all of the current anti androgens which are guaranteed to go systemic and **** you up and make you grow tits we want cb so we can maintain our hair whilst still being men
    This is what is stopping me from adding spiro topical or oral. I'm all for lowering DHT but I don't like the idea of lowering test entirely. Plus I heard it smells bad.

    Leave a comment:

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