CB-03-01 - new antiandrogenic

[simba]

This was there response I got when asking how it is sold:

Hello,
>
> The best thing to do is to look at the new article that we have
> just put up as of a matter of minutes ago. It is extremely thorough and I
> am certain that you will find it interesting. In fact, it is the best
> compilation of information that I have seen on Cortexolone yet. There are
> citations of 17 independent studies.
>
> Thank you,
>
> ID

err.....to me it sounds like theyre avoiding the question because theyre not sure what the best vehicle is.

I sure hope thats not the case, Im really banking on ID CB maintaining my hair until something better comes along

[yan]

Guys this CB is atm totally underrated. You dont seem to understand what I could mean for billions of men worldwide. If it works like promised in the early studies with nearly no side-effects, then this is the damn cure. I understand it isnt a cure for NW4+, but for all low norwoods, thats it. You dont have to think a damn second anymore about hair loss for the rest of your life.

The day they announce the hopefully successful Phase 2 results and the initiation of Phase 3 will be the best day in my life.

[Cob984]

what ur missing is cb officialy from cosmo will hit mkt for hair loss 4-5 yrs away,
by then im toast

on another note, need to find the correct vehicle, right now it dissolves very easy in kb but i dont think it does squat and its bloody expensive,
here hoping iron dragon has figured it out a bit better

[StayThick]

Damn shut the fvck up, Iron dragon only sell LIQUID PREMADE SOLUTION.

How about you STFU. It's clear nobody has received an accurate response from ID themself regarding this. Telling people to shut up when many of us would like answers before grabbing their credit card is annoying. Especially if it could mean potentially buying another useless Indo/Chromo or whatever experimental treatment you want to plug in there.

How about you calm the F down and realize in the wrong vehicle, CB is utterly useless. Useless! Which at that point would only guarantee a dent in your wallet with nothing to show for it. Just playing Devil's advocate here. Point is, people on these forum asks questions to obtain the proper information before making stupid decisions and buying snake oil. That's the point of this forum.

You don't even know what ID is using as a vehicle yet are stating this could be a cure. You say it's a liquid, what liquid? Are you hearing yourself? Get a grip bro... You're losing it and I'm not just talking about your hair.

[lilpauly]

Correct fellas its all about the vehicle . Right now it looks like iron dragon and Kane are the only to suppliers that has cb. I tested Kane's cb and it is fact pure. The problem is we don't know the proper strength and vehicle . I'm hoping this can be solved very soon

[simba]

Correct fellas its all about the vehicle . Right now it looks like iron dragon and Kane are the only to suppliers that has cb. I tested Kane's cb and it is fact pure. The problem is we don't know the proper strength and vehicle . I'm hoping this can be solved very soon

I few pages back yan posted this

Originally Posted by yan View Post
Effectiveness of two vehicles for CB-03-01:


On human skin, in vitro:

~1% CB in Propylene Glycol has an average:

Permeation Rate of 7
Skin concentration of 36


~1% CB in Propylene Glycol and Oleyl Alcohol 9.1 has an average:

Permeation Rate of 1410
Skin Concentration of 231


http://files.investis.com/csm/presen.../RDday2010.pdf - Page 74

On page 7 you can see the timeline they had in 2010. They planned to finish the proof of concept for the alopecia formulation in H1 / 2013. Timeline slipped two years since 2010.. :/


I thought this confirmed that Propylene Glycol and Oleyl Alcohol was the correct vehicle?

[hellouser]

I few pages back yan posted this

Originally Posted by yan View Post
Effectiveness of two vehicles for CB-03-01:


On human skin, in vitro:

~1% CB in Propylene Glycol has an average:

Permeation Rate of 7
Skin concentration of 36


~1% CB in Propylene Glycol and Oleyl Alcohol 9.1 has an average:

Permeation Rate of 1410
Skin Concentration of 231


http://files.investis.com/csm/presen.../RDday2010.pdf - Page 74

On page 7 you can see the timeline they had in 2010. They planned to finish the proof of concept for the alopecia formulation in H1 / 2013. Timeline slipped two years since 2010.. :/


I thought this confirmed that Propylene Glycol and Oleyl Alcohol was the correct vehicle?

No, it was just the vehicle used in the trials.

[simba]

No, it was just the vehicle used in the trials.

Yes but as the permeation rate was so high (and skin concentration) doesnt that mean its the right vehicle?

[hellouser]

Yes but as the permeation rate was so high (and skin concentration) doesnt that mean its the right vehicle?

I wouldt know as I'm not sure what the numbers mean:

~1% CB in Propylene Glycol and Oleyl Alcohol 9.1 has an average:

Permeation Rate of 1410
Skin Concentration of 231

Lucky for me, I do have Oleyl on my and could easily apply CB much like Cosmo has. Do you know what the numbers for intophoresis are?

[simba]

I wouldt know as I'm not sure what the numbers mean:



Lucky for me, I do have Oleyl on my and could easily apply CB much like Cosmo has. Do you know what the numbers for intophoresis are?

In the PDF that was linked to, from page 68 onwards it talks about antiandrogens and the use of cb for acne and alopecia. The numbers for skin permeation for acne are described as permeating the skin well and having a noticeable effect, and even though it doesn't talk about why they used intophoresis or how much it permeated the skin, applying cb to the scalp should permeate as well as on the face(with acne) and will most likely have a decent effect. At the very least its worth using until we find out what vehicle Cosmo is using for current trials.

Now all we need to do is figure out what solution iron dragon is using and we should be set for the next year until new research comes out

[yan]

and even though it doesn't talk about why they used intophoresis

I read in an older presentation that they used it in order to save money and time. If you guys really don`t believe me, I have to search the presentation.

And its true, those permeation tests are like 2 or 3 years old and have nothing to do with the tests performed last year. So atm we have no idea which vehicle is the perfect one.

[simba]

I read in an older presentation that they used it in order to save money and time. If you guys really don`t believe me, I have to search the presentation.

And its true, those permeation tests are like 2 or 3 years old and have nothing to do with the tests performed last year. So atm we have no idea which vehicle is the perfect one.

If you can find it that'll be great, there might be a useful nugget or two of information in there

[yan]

If you can find it that'll be great, there might be a useful nugget or two of information in there

I cant find it anymore. Too much information in those annual reports. Dozens of sites... But I once read every single presentation and there are unfortunately no more information about a vehicle or permeation rate with iontophoresis.

[lilpauly]

Here's my opinion they have a cream for the acne. We used it in the past and no 1 got results because it contained ingredients that would not penetrate the hair shaft like mineral oil . Change the mineral oil to coconut oil for example the it would help get to the hair shaft

[deuce]

I just do not understand all the hype with this cb. No proven results were ever shown in pics. Fellas I hope it does work, but it gets me upset that there is no VISIBLE proof. How in the world would we figure out this vehicle? I think the best hope out there is what joe from staten island said on the bald truth about the newly rejuvinated bimatropost in phase 2 accelerated trials by allergen.