CB-03-01 - new antiandrogenic

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  • yan
    Senior Member
    • May 2013
    • 156

    Originally posted by KeepHoping
    Also even if it only gets you a small amount, do you really need a lot of the product? In the trial it was used once a week right?
    "All subjects were given 5 treatments (in sessions once or twice a week)"



    But strange thing is, the subjects had impressive regrowth even 1 week and 1 month AFTER last treatment. Iontophoresis must be really powerful.
    Imagine if you can achieve that with a topical. You take the stuff twice a week for a month, then stop for a month and have like 40% more follicular density. Would be amazing :P

    And as we all know, DHT needs up to 6 months to destroy those hairs again. Would be amazing if you could take this stuff twice a year for like a month haha. Just a dream I guess.

    The problem is that a topical solution will most probably not be nearly as effective as iontophoresis. So you have to use it maybe daily to deliver the same amount of CB to the hair follicle.

    Comment

    • hellouser
      Senior Member
      • May 2012
      • 4419

      Originally posted by KeepHoping
      Also even if it only gets you a small amount, do you really need a lot of the product? In the trial it was used once a week right?
      It was used twice a week using iontophoresis. Very different. And no, you don't need a lot. 10mg per application gave pretty much the same results as 50mg.

      Comment

      • FearTheLoss
        Senior Member
        • Dec 2012
        • 1581

        I thought cosmo was aiming to have CB on the market by 2016 for hair loss?

        Comment

        • chimera
          Senior Member
          • Aug 2012
          • 171

          Originally posted by FearTheLoss
          I thought cosmo was aiming to have CB on the market by 2016 for hair loss?
          Nope. 2016 is when they think they will be able to release CB for acne. CB for hair loss will take even more time to be released.

          Comment

          • yan
            Senior Member
            • May 2013
            • 156

            Originally posted by FearTheLoss
            I thought cosmo was aiming to have CB on the market by 2016 for hair loss?
            Hm I think the timeline slipped several times in the past.

            early 2015: end of proof of concept (phase 2a)

            ...then maybe phase 2b?

            ...and then at least 18 months for phase 3

            Its more like 2017 - 2018

            They keyword until then is MAINTAIN... I`m currently taking 0.2mg FIN twice a week since 3 months. No side effect (had side effects with 1mg daily) and even thickened up my hair a bit with that small amount. Maybe I`m a good responder, I don`t know... But no debate about fin please. Fin is stone age and needs to get replaced with better stuff. Period.

            Comment

            • hellouser
              Senior Member
              • May 2012
              • 4419

              Originally posted by yan
              "All subjects were given 5 treatments (in sessions once or twice a week)"



              But strange thing is, the subjects had impressive regrowth even 1 week and 1 month AFTER last treatment. Iontophoresis must be really powerful.
              Imagine if you can achieve that with a topical. You take the stuff twice a week for a month, then stop for a month and have like 40% more follicular density. Would be amazing :P

              And as we all know, DHT needs up to 6 months to destroy those hairs again. Would be amazing if you could take this stuff twice a year for like a month haha. Just a dream I guess.

              The problem is that a topical solution will most probably not be nearly as effective as iontophoresis. So you have to use it maybe daily to deliver the same amount of CB to the hair follicle.
              Ideally, it would be best to use a iontophoresis device for the scalp. There needs to be an initiative to find one.... SPECIFICALLY for the scalp.

              Perhaps this also renders skin atrophy impossible?

              Comment

              • hellouser
                Senior Member
                • May 2012
                • 4419

                Originally posted by chimera
                Nope. 2016 is when they think they will be able to release CB for acne. CB for hair loss will take even more time to be released.
                No, 2016 is the absolute earliest date Cosmo could release it. I emailed Cosmo about this in December, 2011:

                Dear XXXXX
                Unfortunately the clinical trials will take some more time. It is unlikely that the product will be in the market before 2016.
                Best regards

                Dr. Chris Tanner

                Comment

                • yan
                  Senior Member
                  • May 2013
                  • 156

                  Originally posted by hellouser
                  Ideally, it would be best to use a iontophoresis device for the scalp. There needs to be an initiative to find one.... SPECIFICALLY for the scalp.

                  Perhaps this also renders skin atrophy impossible?
                  I would certainly be the best! I remember someone wrote he built his own device. But to be honest, I have no idea...

                  Comment

                  • yan
                    Senior Member
                    • May 2013
                    • 156

                    Originally posted by hellouser
                    No, 2016 is the absolute earliest date Cosmo could release it. I emailed Cosmo about this in December, 2011:

                    Dear XXXXX
                    Unfortunately the clinical trials will take some more time. It is unlikely that the product will be in the market before 2016.
                    Best regards

                    Dr. Chris Tanner
                    I checked every single presentation they published. Since 2011, the timeline unfortunately slipped several times... I think this info isn`t accurate anymore. Maybe if they skip phase 2b?
                    Is 2b always necessary? Does someone know?

                    Comment

                    • hellouser
                      Senior Member
                      • May 2012
                      • 4419

                      Originally posted by yan
                      I checked every single presentation they published. Since 2011, the timeline unfortunately slipped several times... I think this info isn`t accurate anymore. Maybe if they skip phase 2b?
                      Is 2b always necessary? Does someone know?
                      Perhaps for an Asian release, which wouldnt be a bad idea, you can always release there and have it imported. Much easier than going to asia for a Replicel procedure.

                      Comment

                      • chimera
                        Senior Member
                        • Aug 2012
                        • 171

                        Originally posted by hellouser
                        No, 2016 is the absolute earliest date Cosmo could release it. I emailed Cosmo about this in December, 2011:
                        Woa, that's great. And I was thinking it would be released around 2020. But just 2 or 3 more years does not sounds that bad.

                        Like how much do you guys think it will cost when it is actually released on the mainstream market?

                        Comment

                        • TravisB
                          Senior Member
                          • May 2012
                          • 188

                          Originally posted by chimera
                          Woa, that's great. And I was thinking it would be released around 2020. But just 2 or 3 more years does not sounds that bad.

                          Like how much do you guys think it will cost when it is actually released on the mainstream market?
                          Yeah, 2016 is not that far away, but it will be version for ACNE.

                          We can't be sure if acne vehicle will be effective against MPB.

                          MPB version will probably come somewhere between 2017-2019 (if ever)

                          Comment

                          • hellouser
                            Senior Member
                            • May 2012
                            • 4419

                            Originally posted by TravisB
                            Yeah, 2016 is not that far away, but it will be version for ACNE.

                            We can't be sure if acne vehicle will be effective against MPB.

                            MPB version will probably come somewhere between 2017-2019 (if ever)
                            If the acne vehicle penetrates skin and can get to the hair follicle, it will work.

                            Comment

                            • TravisB
                              Senior Member
                              • May 2012
                              • 188

                              Originally posted by hellouser
                              If the acne vehicle penetrates skin and can get to the hair follicle, it will work.
                              It would be great!

                              Hopefully it won't be a prescription medication so we'll be able to just buy it anytime we want.

                              However it probably will be prescription unfortunately since it's steroidal.

                              Comment

                              • Conpecia
                                Senior Member
                                • Sep 2011
                                • 904

                                Guys why aren't we focusing on the fact that we HAVE CB NOW?? Meaning we need to find the correct vehicle and dosage. We also need to see how much CB is in what Iron Dragon is selling. Waiting until 2016 seems strange when it's allegedly right here...

                                Comment

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