CB-03-01 - new antiandrogenic

[burtandernie]

There is a lot riding on this thats for sure. If this doesnt happen finasteride will be the treatment of choice for a long time to come.

[FearTheLoss]

What did the e-mail from them say?

I think the presentation linked to in a previous post is saying that they are currently doing pre-trial preparations for the Phase II alopecia (enrolling study participants, finalising the vehicle etc). That's why it's about a third of the way through the Phase II column. I have not seen anything from Cosmo to suggest they have actually started giving patients the drug yet - has anybody else?

The spin-off is actually a good thing because it means they can launch a fresh round of funding and actually get the money to run Phase III for acne and Phase II for alopecia (as well as their new drug for genital warts, which maybe we will all need by that time after we start getting laid all the time with our new heads of hair )

It's only a partial spin-off so Cosmo will still have majority ownership of it. It shows a real commitment by Cosmo to CB which is great. They are about the only company out there with both the money and the desire to follow their new drug through.

I posted it somewhere in this thread, but I asked them how it was coming along and they said they were well underway with phase II trials.

Doke: lol, we don't have a single study to suggest any positive or negative affects of RU on hairless and other parts of the body, making a claim like this is a little outrageous.

[MancBoy]

The spin-off is actually a good thing because it means they can launch a fresh round of funding and actually get the money to run Phase III for acne and Phase II for alopecia (as well as their new drug for genital warts, which maybe we will all need by that time after we start getting laid all the time with our new heads of hair )

It's only a partial spin-off so Cosmo will still have majority ownership of it. It shows a real commitment by Cosmo to CB which is great. They are about the only company out there with both the money and the desire to follow their new drug through.

Yeah I'm not saying it's fully negative I just mean that new shareholders tend to want one thing - PROFIT. So if it's PE (who typically are the ones who are transacted in private placements) then if results aren't awesome then they can lose patients very quickly.

But hopefully they go the route of IPO and I'll be buying in...try and make some money back from however expensive this product may be!! ha

[LMS]

To be honest cb may or maynot be better than ru and now you can even get premade at ru solutions and anagen, and the powder to make your own at this time its better than anything.

Agreed. Its saving grace is of course is non systematic activity. I get sides on RU.

[doke]

To be honest cb may or maynot be better than ru and now you can even get premade at ru solutions and anagen, and the powder to make your own at this time its better than anything.

[Pate]

by the looks of things, also going off the email I received from them about a month ago, they are doing an 18 month phase II trial that is 6 months underway. In this case, if everything goes as planned, there's a year left of phase II and then we will see results/know vehicle I believe. Furthermore, this suggests that maximum, we would have 3 years until CB is publicly released. (12 more months phase II, 6 months give or take to get phase III ready, 12 months phase III, 6 more months until release, being generous)

What did the e-mail from them say?

I think the presentation linked to in a previous post is saying that they are currently doing pre-trial preparations for the Phase II alopecia (enrolling study participants, finalising the vehicle etc). That's why it's about a third of the way through the Phase II column. I have not seen anything from Cosmo to suggest they have actually started giving patients the drug yet - has anybody else?

The spin-off is actually a good thing because it means they can launch a fresh round of funding and actually get the money to run Phase III for acne and Phase II for alopecia (as well as their new drug for genital warts, which maybe we will all need by that time after we start getting laid all the time with our new heads of hair )

It's only a partial spin-off so Cosmo will still have majority ownership of it. It shows a real commitment by Cosmo to CB which is great. They are about the only company out there with both the money and the desire to follow their new drug through.

[FearTheLoss]

Yeah I should of been clearer a spin off isn't termination but still they'd be handing profits to someone else in order to raise cash for their other business. Therefore they value colon as a more valuable business (or less risk). Also if you spin off it could take the company away from a strong cash rich business to a PE firm that maybe less willing to put in any extra cash. But that sounds negative so to be positive it could go somewhere that would really push it!! So if they are in phase two how long do we think until market??

But my point about spin off is if you knew you had a winning lottery ticket, why would you share the winnings??

by the looks of things, also going off the email I received from them about a month ago, they are doing an 18 month phase II trial that is 6 months underway. In this case, if everything goes as planned, there's a year left of phase II and then we will see results/know vehicle I believe. Furthermore, this suggests that maximum, we would have 3 years until CB is publicly released. (12 more months phase II, 6 months give or take to get phase III ready, 12 months phase III, 6 more months until release, being generous)

[Sogeking]

Someone posted before, they plan to end phase 2 trials by the end of the next year. After that we just have to wait to see when will phase 3 start. If they enter phase 3 it becomes a lot more likely they will push it to market.

[JZA70]

Ease of access, could modify it slightly to make it able to penetrate the skin. Could also end up being cheaper etc.

It's going to have a lot of ingredients in it that will make it useless as a topical.

[rdawg]

Must not get excited about this! How are the acne trials getting on? Wasn't there potential for a product on the market (for acne) by the end of the year? I'm aware it's a cream based product that isn't appropriate for hairloss.

1 more year or so until the acne trials are done, phase III is about to begin i'd assume.

[rdawg]

What really is the use if the acne version did come out? I mean what good is that really almost nothing about it is much relevant to MPB

Ease of access, could modify it slightly to make it able to penetrate the skin. Could also end up being cheaper etc.

[burtandernie]

What really is the use if the acne version did come out? I mean what good is that really almost nothing about it is much relevant to MPB

[Borealis]

Must not get excited about this! How are the acne trials getting on? Wasn't there potential for a product on the market (for acne) by the end of the year? I'm aware it's a cream based product that isn't appropriate for hairloss.

[ShookOnes]

CB can already be bought, but we do not know which vehicle really works.
If we can find out, which vehicle was used in the trials, we could mix it ourselves and would not need to wait for phase 2 trials, FDA approval, market release, etc.
Or we must find out ourselves, which vehicle works very well.
But how could any of that be achieved?

it can't. so wait.

[Xoxo]

CB can already be bought, but we do not know which vehicle really works.
If we can find out, which vehicle was used in the trials, we could mix it ourselves and would not need to wait for phase 2 trials, FDA approval, market release, etc.
Or we must find out ourselves, which vehicle works very well.
But how could any of that be achieved?