Where are the phase IIb results for Bimatoprost?

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  • champpy
    replied
    Yes because they were assuming that it was secretly being phase 3 tested now, which would allow it to be released at yrs end. But that is speculation. There is no way of knowing if any further tests have been done since the end of phase 2. They wont divulge jack crap about this product

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  • burtandernie
    replied
    In terms of preventing hair loss I wonder how good this will work. I guess we need to see some results to know that though. I feel like this is gonna be pricey so it might still be better to go propecia first instead of this if it does come out. Propecia gonna be much more cost effective in terms of keeping hair. This probably more like a rogain in terms of growing new hair.
    So timeline for this stuff if it worked well still has to start and get through a phase 3 so atleast 1 year or more away? I thought someone said it might come out this year

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  • champpy
    replied
    No i get ya 2014already, i really do. I think we need to just ease up just a bit on the assuming thats whats going to happen. Its common knowledge that there was a phase 2. Anyone who was planning on competing with allergen based on a bim treatment could have already done so, based off the fact allergens taken it to a phase 2. Hell i dont see why other companies havent already tired this. Its been well known for awhile that bim may help w hairloss, but noones ever shown success w a trial. At least not that weve seen. Maybe other companies are being cheap and waiting for allergen to pay for all the testing, then they will jump on the bandwagon after its been proven to work. I just dont see why no other company has tested out a higher percentage on even one person. If they did, and it worked, you can bet they would be developing this also. It would be a race to see who could do it first.
    I think its more of a possibility that setit is the real winner, and bim is just a boost to their propsed treatment by offering a little more regrowth than minox.

    Man Im just tired of this game. Getting hopes up over and over and getting pooped on each time is crushing. Dude i hope your right. Just think someone somewhere wouldve shown results by now

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  • JayM
    replied
    Great posting 2014. It is appreciated. Wish they would hurry up as I type blowing a hair off my screen aha.

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  • It's2014ComeOnAlready
    replied
    Originally posted by champpy
    I dont see how showing thats its in the mid to late stage development category means that they are moving forward. We know that it finished phase 2. Thats past midway. Isnt that all that page was showing, products that are at least in mid stage development? Idk, i dont see that as much to get excited about
    Look, I don't mind explaining things to help people out, but c'mon and help me out here.

    It has been debated for the better part of a year whether or not this drug has succeeded in phase 2b. Months and months later, it is mentioned alongside with Kybella (which has launched), and two acne drugs in late phase 3 studies. It is highlighted in the late stage aesthetic drugs. If you notice, there are 27 drugs being developed for aesthetics, but they chose deliberately to mention bimatoprost for hair growth.

    If they weren't continuing with the program or planning to release it, then there would be no mention at all. Instead, it is there, right next to a drug that has already launched, and two drugs that have already been engaged in phase 3 studies.

    They've also recently stated publicly that they've chosen to move forward with 70 projects, and if you notice, the total number of programs there is 70!

    I've posted before about seti and bim, and this proves my ideas to be correct on the matter. They are going to be used together to tackle hair loss, and they will corner the market by doing so. One stops hair loss, the other regrows, and the result should be a complete reversal of hair loss if in the early to mid stages. It also means they are close to a release for bim.

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  • champpy
    replied
    I dont see how showing thats its in the mid to late stage development category means that they are moving forward. We know that it finished phase 2. Thats past midway. Isnt that all that page was showing, products that are at least in mid stage development? Idk, i dont see that as much to get excited about

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  • rdawg
    replied
    Originally posted by It's2014ComeOnAlready
    BIM IS ALIVE.

    Otherwise they would've never mentioned it in their presentation. That is a great indication that they are moving forward with it.

    Anyone who's interested - click on the Q2 2015 Earnings Presentation Page 23 -

    http://ir.allergan.com/phoenix.zhtml...-presentations
    Yup definitely still have it on their pipeline it seems!

    Just gotta wonder whats going on there behind the scenes.

    too many positives about this product not to move forward to phase III for hairloss, it's gone to Phase III/approval on two other applications already (eyelash growth and glaucoma)!

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  • It's2014ComeOnAlready
    replied
    Originally posted by burtandernie
    How do they determine if this is going to be OTC or by prescription only? Maybe wishing too much but it would be nice to see something on a shelf by rogain where I can make the decision verses some doctor who most likely doesnt keep up on or know much about hair loss. I dont blame them hair loss is a pretty minor thing compared to the stuff they routinely deal with.
    Having to pay to see the doctor for something you know want before you even go and having to convince them is pretty annoying. If they say no you have to change primary care doctor, and go try again. Pretty silly process honestly since most docs are barely qualified to even make that call
    I hope it's OTC, I mean, it makes more sense to do it that way. If you get a prescription, it limits the number of bottles you can buy. Also, if it's OTC, it's more accessible to more people, and you can buy as many bottles as you want. They def make more money going OTC

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  • burtandernie
    replied
    How do they determine if this is going to be OTC or by prescription only? Maybe wishing too much but it would be nice to see something on a shelf by rogain where I can make the decision verses some doctor who most likely doesnt keep up on or know much about hair loss. I dont blame them hair loss is a pretty minor thing compared to the stuff they routinely deal with.
    Having to pay to see the doctor for something you know want before you even go and having to convince them is pretty annoying. If they say no you have to change primary care doctor, and go try again. Pretty silly process honestly since most docs are barely qualified to even make that call

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  • maver1ck
    replied
    Originally posted by It's2014ComeOnAlready
    BIM IS ALIVE.

    Otherwise they would've never mentioned it in their presentation. That is a great indication that they are moving forward with it.

    Anyone who's interested - click on the Q2 2015 Earnings Presentation Page 23 -

    http://ir.allergan.com/phoenix.zhtml...-presentations

    Leave a comment:


  • It's2014ComeOnAlready
    replied
    BIM IS ALIVE.

    Otherwise they would've never mentioned it in their presentation. That is a great indication that they are moving forward with it.

    Anyone who's interested - click on the Q2 2015 Earnings Presentation Page 23 -

    Leave a comment:


  • It's2014ComeOnAlready
    replied
    Originally posted by Tomtom21
    Go to allergans website, find the presentations page and click to view the pdf of the Q2 conference call. Its on page 23 of the presentation. The thing with kythera is page 11
    lol could've just sent me a link! Thanks dude!

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  • Tomtom21
    replied
    Go to allergans website, find the presentations page and click to view the pdf of the Q2 conference call. Its on page 23 of the presentation. The thing with kythera is page 11

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  • It's2014ComeOnAlready
    replied
    Originally posted by burtandernie
    Is BIM going to provide some protective effect against androgens too? I thought someone mentioned it might just be needed a few times a week instead of everyday. I guess that includes the huge assumption that it works or ever comes out.
    Yes. Because of the increased paracrine (cell-to-cell) signaling, as well as increased production of melanocytes and keratinocytes.

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  • It's2014ComeOnAlready
    replied
    Originally posted by Tomtom21
    This is my speculation and yes it is a speculation so take it as you'd like. 2014 tell me your opinion. I find it hard to believe it is dead when they have bim for hair loss listed as one of there products in late stage development for aesthetics in their presentation. Further review shows that they made mention of kythera's product aga for R&D. So at that alone i dont feel that bim is dead in the water. Further speculation and again i could completely out of my element here as i have linited knowledge on patents, but wasnt part of the issue with bim patent rights? Whereas, other companies would be capable of producing it? If thats the case maybe they intend to make a dual topical of seti + bim and patent it together as their acquisition of kythera grants them exclusive rights to anti pgd2. Of course they would still need to prove efficacy of seti which for us would delay development of a product. However, im sure i read on this thread before a quote from cots saying a topical of pgd2 blocker would be ideal and that in conjunction with bim would be the "foot off the brake and flooring the gas." Again guys this is all speculation and quite optimistic as we are all in the same boat here. Personally i have my faith in samumed as all these stem cell and regeneration studies point to the wnt pathway. Cheers fellas hopefully good news is on the horizon! Hang in there!
    Where did you see that?

    Anyway, I do agree with you on most points. Glad some ppl here are informed.

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