Bimatoprost finishing up Phase IIb trial!

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  • inbrugge
    replied
    5% Bim FTW. (lol)

    Leave a comment:


  • charlie76761
    replied
    Originally posted by noisette
    Hello guys,
    I'm also excited for the results, perhaps in a few days

    I don't know if you have seen this one too . It was a clinical trial for women baldness.... but a phase 2 finished on March 2014. You will see the results , vehicule for bimatoprost... Have you some informations about the next phase ?

    https://clinicaltrials.gov/ct2/show/...ct=X30156#evnt

    v interesting - thanks Noisette... seems BIM vehicle on its own beat 2 of the 3 BIM topicals on the Target Area Hair Count metric. Be interesting to understand the concentrations of BIM topicals. Min at 2% was far superior to all

    Diffuseloser - i got my BIM from Kane - for half a G, he charges $500 then applies any discount as per his VIP system (i got 15%).

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  • noisette
    replied
    Hello guys,
    I'm also excited for the results, perhaps in a few days

    I don't know if you have seen this one too . It was a clinical trial for women baldness.... but a phase 2 finished on March 2014. You will see the results , vehicule for bimatoprost... Have you some informations about the next phase ?

    Leave a comment:


  • hellouser
    replied
    Originally posted by rdawg
    Yea it's pretty much been stated that .03% is too weak of a dose by bim for hairloss, they seemed to imply that they had mixed results in the 2A phase which is why they raised it.

    I'd imagine you get a much higher response rate at a higher dose, which is why im excited for the results!
    What happens if the results still suck at even 10% concentration?

    Leave a comment:


  • rdawg
    replied
    Originally posted by unbalding

    I've been using .03% for about two weeks now, and I can't say there's been any change. I can't wait to find out the optimal dosage when the latest trial is released, and then I will consider buying some powder to mix.
    Yea it's pretty much been stated that .03% is too weak of a dose by bim for hairloss, they seemed to imply that they had mixed results in the 2A phase which is why they raised it.

    I'd imagine you get a much higher response rate at a higher dose, which is why im excited for the results!

    Leave a comment:


  • diffuseloser
    replied
    Good man - keep us updated. How much did you pay for your Bim, if you don't mind me asking?

    Leave a comment:


  • charlie76761
    replied
    Interesting stuff indeed.

    re taking with antiandrogen and higher dose BIM:

    I have 500mg on it's way over from China plus 3g of CB and some OC. Will be looking to use between 0.25% of BIM plus c. 3% of CB, and TBC % OC

    Will take baseline photos before and then at 3 mths

    Not sure of vehicle as was thinking of using Neog that i've been on since Oct but really not to sure if it's helping - it def makes your hair shaft thicker but I'm a lot more scalpy at the back of my head. It does work as vehicle for delivery as i was trying to use RU but get fairly harsh sides (hence the CB ... altho might add 10/20mg of RU if needed as pre-caution given 5% 2x ED for CB in current trails... also have 500mg of Fin but, for me, that's a last resort for topical anti-a).

    As you can see my tactic is to hit from all angles - not great for working out what the main driver of results is, but think is a better tactic for growth

    Will prob drop neo or reduce dosage and stick to PG/Eth

    Great no sides on BIM reported in this study - a little bit concerned over loss of iris colour plus one user on ******* report 'floaters' in his eyes that became perm. Also take confidence from IIb apparently being at these v high % - they must be fairly confident that such sides arent an issue as they'd be potential show-stoppers

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  • Hairismylife
    replied
    Originally posted by unbalding
    Good find. They got some impressive results, and they only used .03%. I'd love to see what this stuff would do at a higher concentration, and combined with RU.

    In 17 weeks total hair count increased 27.4%, with the best responder out of 6 getting an increase of 112.5%.

    One sour note is that it appears only one person got truly impressive results. The average increase in hair counts is only 8.65% if you remove the single outlier of 112.5%.

    Terminal hair counts increased 12.1% after 17 weeks.

    The vellus hair count increased by 78.1% after 17 weeks. Again though, the positive results were mainly the result of a single outlier showing an improvement of 406%.

    No side effects were recorded.


    Out of 9 subjects in two groups it looks like one person got phenomenal results, at least two people got no results, and the rest it seems got moderate results. This is very promising indeed.

    I've been using .03% for about two weeks now, and I can't say there's been any change. I can't wait to find out the optimal dosage when the latest trial is released, and then I will consider buying some powder to mix.
    This result hasnt taken into account combined usage with
    other treatment. If it combined with anti-androgen, the result may be greater.

    Leave a comment:


  • unbalding
    replied
    Originally posted by noisette
    Have you seen this clinical trial by Duke University? There are results published on July 2014.

    https://clinicaltrials.gov/ct2/show/...ect=X01256#all
    Good find. They got some impressive results, and they only used .03%. I'd love to see what this stuff would do at a higher concentration, and combined with RU.

    In 17 weeks total hair count increased 27.4%, with the best responder out of 6 getting an increase of 112.5%.

    One sour note is that it appears only one person got truly impressive results. The average increase in hair counts is only 8.65% if you remove the single outlier of 112.5%.

    Terminal hair counts increased 12.1% after 17 weeks.

    The vellus hair count increased by 78.1% after 17 weeks. Again though, the positive results were mainly the result of a single outlier showing an improvement of 406%.

    No side effects were recorded.


    Out of 9 subjects in two groups it looks like one person got phenomenal results, at least two people got no results, and the rest it seems got moderate results. This is very promising indeed.

    I've been using .03% for about two weeks now, and I can't say there's been any change. I can't wait to find out the optimal dosage when the latest trial is released, and then I will consider buying some powder to mix.

    Leave a comment:


  • unbalding
    replied
    Originally posted by Illusion
    Yeah I wonder when they're going to publish results... As far as I know, the study is finished in january so I don't know how long it takes to collect and publish data? I could be wrong though about the study itself being finished in january and not necessarily the results being posted in january.
    The trial was scheduled to complete in November, and the results should be finalized in January. If they report the results immediately we should have them in a matter of weeks.

    Leave a comment:


  • Gjm127
    replied
    Originally posted by noisette
    Have you seen this clinical trial by Duke University? There are results published on July 2014.

    https://clinicaltrials.gov/ct2/show/...ect=X01256#all
    How come we haven't seen this yet if it was published months ago?
    Results are very good with 0.03%... I can't imagine what higher concentrations would yield!

    This is a Duke University study and it says it's for Phase 2. It's been completed with great results. Phase 2? They're actually going through the FDA gates?

    Is Latisse coordinating it? How about the trials that were supposed to be completed in January '15?

    Results Point of Contact:
    Name/Title: Dr. Elise Olsen
    Organization: Duke University Medical Center
    phone: 919-668-5613
    e-mail: elise.olsen@dm.duke.edu

    Can we contact her and find out more?

    Leave a comment:


  • noisette
    replied
    Have you seen this clinical trial by Duke University? There are results published on July 2014.

    Leave a comment:


  • Illusion
    replied
    Yeah I wonder when they're going to publish results... As far as I know, the study is finished in january so I don't know how long it takes to collect and publish data? I could be wrong though about the study itself being finished in january and not necessarily the results being posted in january.

    Leave a comment:


  • joel203
    replied
    Does anyone know the date clinical trial results are released?

    Leave a comment:


  • luca10
    replied
    Anxious

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