WCHR 2014 Presentations (Community-funded)

[nameless]

@hell - are you serious that all we need is $2M - 20M to fund Cotsarelis and Follica?

If answer = yes, than will the real hellouser please stand up please standup... because you're clearly an alien, if it was only $2M then hairloss would be solved and Cotsarelis would already be rich.

I suspect Cotsarelis just wants to be funded to the tune of $2M for the next couple of years.

If it were true he's have $100M in the bank right now. I will not spend a cent on Cotsarelis via crowdfunding. Its a bad use of money.

We'd be MUCH better of crowdfunding Histogen.

I know. It's crazy to think that with all the people out there who invest money into things why would Cotseralis not be able to get $2 million lousy dollars if he has a better moustrap and he has completed phase 2 and he only has phase 3 to go?

Desmond could you please ask Cotseralis why he can't get $2 million from professional investors if he has a better mouse trap that has already completed phase 2 and only has to do a phase 3?

Some of us don't understand. If it made sense some of us would be interested but it doesn't make sense. I like the idea of doing a crowdfunding for a phase 3 with significantly better results than minox/propecia but when I see that the amount needed is a mere $2 million I don't understand why he's having trouble.

[hellouser]

Guys this is a very technically intensive congress. A lot of information is being presented. I will let you sieve through the data at your own pace. So don't worry the technical information is being presented.

As for the 2 year timeline, that's preclinical work. You need to add at least 6 more years for clinical trials unless the compound already existed on the market, which may be!

Idea:

Use Dr. Lauster's team's innovations with creating follicles to test for existing compounds that have the same effect to halt miniaturization of follicles. If only Dr. Lauster would allow that though... progress would speed up incredibly.

[Desmond84]

Hey Hell

Yes I did. I will email him tonight.
Thank you

Joachim, I did go to the talk but didn't record it. Really sorry brother. I got caught up chatting with a researcher and didn't make it to the room in time to record the talk. I'll give you a summary of what was press Ted tonight though. Plz remind me. Cheers.

Jahodas team is presenting in about 2 hours. Arashi I've got the gear ready brother. I'm recording it no matter what lol

[nameless]

Guys this is a very technically intensive congress. A lot of information is being presented. I will let you sieve through the data at your own pace. So don't worry the technical information is being presented.

As for the 2 year timeline, that's preclinical work. You need to add at least 6 more years for clinical trials unless the compound already existed on the market, which may be!

Desmond are you saying that you ARE getting the technical information how to culture mass pass dp cells/epithelial cells while keeping the hair inductivity/trichogenicity? If you are getting that information you are my hero.
And if there's a way to get the information in a study that would be great too.

But one thing has bothered me is that it doesn't make sense that these folks would release all of their technical information because their competitors can use it to get a leg up on them. I wonder if they're really sharing everything that we would need to know.

[hellouser]

Hey Hell

Yes I did. I will email him tonight.
Thank you

Joachim, I did go to the talk but didn't record it. Really sorry brother. I got caught up chatting with a researcher and didn't make it to the room in time to record the talk. I'll give you a summary of what was press Ted tonight though. Plz remind me. Cheers.

Jahodas team is presenting in about 2 hours. Arashi I've got the gear ready brother. I'm recording it no matter what lol

I emailed Jahoda as well a few days ago, didn't hear from him. Any chance you could get to chat with him one on one?

Thanks Desmond!!

[nameless]

hi desmond,

if you find the time, i would appreciate it if you can listen to the speech P146, starting 9.40AM.
sounds like a new device for hair transplants... with 3 needles or so.
i'm curious what they are talking about. maybe it enables better HT yields, or reduce trauma and redness. maybe it enables more density for HTs, because needle thickness is key here. if lauster comes up with hair cloning someday, HT implanting techniques definitely should be improved to enable great density. maybe this device goes into that direction.

if you find the time to record it, would be cool.

thanks

+ 1

When I thought Nigam was going I emailed him and asked him to go to this presentation. This could be very important. They seem to be saying they have found a better way to implant this kind of tissue with a much higher survival rate. This one was on Desmond's original list of 6.

[Desmond84]

Idea:

Use Dr. Lauster's team's innovations with creating follicles to test for existing compounds that have the same effect to halt miniaturization of follicles. If only Dr. Lauster would allow that though... progress would speed up incredibly.

That is exactly what they're planning ;-)

[nameless]

I emailed Jahoda as well a few days ago, didn't hear from him. Any chance you could get to chat with him one on one?

Thanks Desmond!!

+1

It would be great if you could bring home all of the details how to turn regular fibroblast cells into hair growing cells.

[hellouser]

That is exactly what they're planning ;-)

That's awesome! Having a testbed like that will FINALLY determine efficacy of compounds before going to trials. Hell, I wonder if such topicals will even need to be further tested on humans if we have skin and follicles to work with. Clinical trials could be reduced drastically.

[nameless]

That's awesome! Having a testbed like that will FINALLY determine efficacy of compounds before going to trials. Hell, I wonder if such topicals will even need to be further tested on humans if we have skin and follicles to work with. Clinical trials could be reduced drastically.

Hellouser the FDA is still going to force these products to go through regular human trials. I don't see where it helps us if they are going to use this technology to create follicles to test treatments on. I think that this technology would serve us better if it was used to create follicles for later implantation into our scalps.

[oppenheimer82]

jarjar could you please stop spamming. thank you.

[Arashi]

Jahodas team is presenting in about 2 hours. Arashi I've got the gear ready brother. I'm recording it no matter what lol

Super exciting stuff !! Good luck again Desmond ! And it would be terrific if you could manage to ask Gardner and/or Higgins some questions !

[NeedHairASAP]

I'm 2000% sure if these guys crack the code we wont have to wait 8 years for trials. Maybe a few years. These german docs are smart and they will set up shop somewhere in asia or india or africa and give treatments.

[HairlossAt15]

Desmond, if you talk to Cotsarelis again could you bring up the point that MPB sufferers do not need brand new follicles because we still have all our hair it is just miniaturised etc and pgd2 is what he believes to be doing that so why is he/Follica/Some other company(he has mentioned he has been approached by many) are not rushing full steam ahead with the pgd2 trials. Did he mention why they havent started (the pgd2 clinical trials)? If the PGD2 is not dealt with wouldnt the new follicles being created (by these other techniques) be affected by it again and just start miniaturising just like the original hairs? You could bring up that last point to other people you talk to as well.

I would be very thankful but you have already done enough its up to you, sorry for the late request.

[sdsurfin]

question for desmond

Super exciting stuff !! Good luck again Desmond ! And it would be terrific if you could manage to ask Gardner and/or Higgins some questions !

Desmond- Since you probably have the best idea of who has made the most progress so far and who needs funding the most- could you start thinking about where the best place to direct a crowdfunding effort would be? Something about cotsarellis rubs me the wrong way- he seems reluctant to work with others and his claims and predictions always seem a bit weird and contradictory. That being said, a 2M goal to bring a new treatment to market seems like a plausible and effective goal, and if we can follow up with him and see if he's really into a crowdfunding effort, let's do it! I think we could easily raise that amount.

With a well advertised campaign, I bet you could even raise the 20 million pretty easily, it just needs to be tied to a legit research team who is willing to help promote it, and get it into the right hands. Funding for science and medicine is actually low and hard to get in the USA in general, so I don't think he's being as devious as most people seem to believe. Dr. Xu is great but I'm not sure if he's the most advanced as far as where he's at with hair regeneration research. My guess is that funding a team or company that has a clear goal of bringing something to market is the best option. I would not latch on all kinds of demands etc etc, you're just going to push away whoever you're trying to work with. Just pick a good horse and run with it. So far Dr. Xu is the only one who has even considered getting involved in a crowdfunding effort, which is why I've been focused on him.

I don't think it's as complicated a process as many on here would have us believe. It will just require a few people to organize it and get it going, and the worst that can happen is we raise some money and not all of it. Indiegogo is very straightforward and most of the questions that people have raised about crowdfunding are a moot point. The important part is having someone to work with/for that can provide their public face and some brief info/video/photos etc to get people excited. If anyone has made a kickstarter before they will know that it is not rocket science, and usually doesn't require many people to set it all up.

What did the germans say about their funding? Are they well set? any news from tsuji lab? it's been years since they made the news, what are they up to? Desmond maybe you can ask around about them...
Also, you seem to be pretty sure that having a cure by the early 2020's is plausible, and I'd really like to know, beyond your general optimism, what statements by researchers are you basing this on? So far it doesn't seem like you've talked to anyone that has given that kind of timeline. I'm not saying it isn't possible, but a lot of people on here get excited by your optimism, and in the end I'm kind of wondering if you've taken the time to sit down and think about how long this kind of stuff actually takes. I mean they were saying they'd have a cure in five years when my grandfather was young. I find stem cell science fascinating too, but I feel like we're in model-T days, and regrowing thousands of tiny organs is still so far off as a day to day possibility. Any info you gathered that sheds light on where we're at will certainly be appreciated, cause so far I haven't learned anything new. thanks for your hard work!