Final Days: Chinese Scientists Have Solved the DP Culturing Problem! (2014)

[ar50]

Jesus, if we actually did bypass all the regulations ourselves in a stem-cell lenient country we'd have the funds in a matter of WEEKS from a crowdfunding campaign.

lets go to somalia. There is no government or FDA over there. Or the Krim. I think mister putin would like us to start a company over there.
Hell, looking at his head, he will even support us and chip in few millions of his gazprom money

[hellouser]

I like your idea. maybe a bit off topic but wasn't there a thread about some kind of a kickstarter for the chinese guy who was behind this? I really want to give money man. Monthly. no problem. but how big do you think the impact of our donations will be? because im not sure how many guys there are on this forum and i dont know about how much the rest wants to chip in.

Jesus, if we actually did bypass all the regulations ourselves in a stem-cell lenient country we'd have the funds in a matter of WEEKS from a crowdfunding campaign.

[ar50]

It's not good because they're not paying attention to the discoveries being made outside of their own labs. Imagine if they never got around implementing someone else's technique that they needed to finally crack it all?

We'd basically be stuck for years to come... then again, we'll probably be stuck for years to come regardless seeing how the public and investors are too lazy to a) give a shit b) fund a project c) seek for REAL solutions past crap like fin or minox and of course, all the red tape from governing bodies of scumbags like the FDA that will stall progress for as long as they can.

We'd be better off funding the whole thing ourselves, going to a remote country, setting up a clinic and bypassing the stupid regulations.

I like your idea. maybe a bit off topic but wasn't there a thread about some kind of a kickstarter for the chinese guy who was behind this? I really want to give money man. Monthly. no problem. but how big do you think the impact of our donations will be? because im not sure how many guys there are on this forum and i dont know about how much the rest wants to chip in.

[hellouser]

Why isn't it good for us?

I think it might be good for us if I understand it correctly. It sounds like she's saying that the other groups are doing it differently than the Jahoda group and that could mean that they've discovered something that the Jahoda group isn't even aware of. And that could be good because there may be limitations to Jahoda's method.

It's not good because they're not paying attention to the discoveries being made outside of their own labs. Imagine if they never got around implementing someone else's technique that they needed to finally crack it all?

We'd basically be stuck for years to come... then again, we'll probably be stuck for years to come regardless seeing how the public and investors are too lazy to a) give a shit b) fund a project c) seek for REAL solutions past crap like fin or minox and of course, all the red tape from governing bodies of scumbags like the FDA that will stall progress for as long as they can.

We'd be better off funding the whole thing ourselves, going to a remote country, setting up a clinic and bypassing the stupid regulations.

[Randomb]

I don't really understand all the scientific terms lol can someone simplify what the Chinese scientists have done?

[kobefan234]

All in favor of changing the thread title to "Final decades: ..."

sadly this

[nameless]

Part in bold isn't good for us.

Why isn't it good for us?

I think it might be good for us if I understand it correctly. It sounds like she's saying that the other groups are doing it differently than the Jahoda group and that could mean that they've discovered something that the Jahoda group isn't even aware of. And that could be good because there may be limitations to Jahoda's method.

[hellouser]

Reply from Jahoda's team:



Sorry for the slow reply I’ve been away on holiday.



I’m not up to speed as to why the various other groups are using their techniques, hopefully will be able to get an update on their work at an upcoming conference. As to why they might use single cell populations, I guess just to identify key promoters in each population. Mixing cultured populations in a 3D model is something that I’m currently working on but currently not at the stage where we can assay inductiveness in vivo.

Maintaining the inductivity seems to go hand in hand with reducing the cells proliferation, when in a matrix/3D model the DP slow down their proliferation and this may have something to do with partially restoring their inductivity. Our current thinking is to rapidly expand the DP in culture then revert them to their inductive state. As to what will happen if we do get follicles successfully forming in vivo I’m not sure if they themselves will miniaturise over time, I think that’s a question for a later date.

Not sure on time courses for treatments, I can see things moving onwards but not sure what if any problems will arise over time.


Cheers,

Aaron Gardner

Part in bold isn't good for us.

[cichlidfort]

Interesting.

But it's also true that puberty starts for different boys at different ages and ends at different ages. And even after hair loss starts it takes awhile for the damage to start damaging a person's looks. Dermatologists say that we are missing about 20% of our hair before we even notice. And as you age you produce less of the hormones that take your hair. You would not need to be retreated more than every 5 - 10 years even if the new hair was susceptible to androgen if they can turn the clock back on the new hair to the point where it was at before it started falling out.

Surprisingly, I noticed my hairloss the second it started. I noticed abnormal shedding in the shower. I was instantly worried about losing hair and drove myself mad. Baldness couldn't be a thing with me. In addition, everyone thought I was insane for questioning if I was losing hair. I use to have such great thick straight hair. I still have about half or so left and for most people, they wouldn't even notice but to me, it's like night and day.

[nameless]

Reply from Jahoda's team:



Sorry for the slow reply I’ve been away on holiday.



I’m not up to speed as to why the various other groups are using their techniques, hopefully will be able to get an update on their work at an upcoming conference. As to why they might use single cell populations, I guess just to identify key promoters in each population. Mixing cultured populations in a 3D model is something that I’m currently working on but currently not at the stage where we can assay inductiveness in vivo.

Maintaining the inductivity seems to go hand in hand with reducing the cells proliferation, when in a matrix/3D model the DP slow down their proliferation and this may have something to do with partially restoring their inductivity. Our current thinking is to rapidly expand the DP in culture then revert them to their inductive state. As to what will happen if we do get follicles successfully forming in vivo I’m not sure if they themselves will miniaturise over time, I think that’s a question for a later date.

Not sure on time courses for treatments, I can see things moving onwards but not sure what if any problems will arise over time.


Cheers,

Aaron Gardner

Looks like Arishi was wrong about the Jahoda team. He was so sure that they have a major advance over their last presentation as he was so sure all the presenters have a major advance over Jahoda's previous presentation. Jahoda says rapid proliferation of cells causes loss of trichogenicity but Jahoda's strategy is now to utilize rapid proliferation of cells, resulting in the total loss of trichogenicity, and then trying to restore the trichogenicity.

the part about him trying to restore the trichogenicity after it's lost looks like Jahoda is going back to the drawing board because his previous paper involved protecting the trichogenicity that was already inherent in the cells.

[sdsurfin]

news from gardner

Reply from Jahoda's team:



Sorry for the slow reply I’ve been away on holiday.



I’m not up to speed as to why the various other groups are using their techniques, hopefully will be able to get an update on their work at an upcoming conference. As to why they might use single cell populations, I guess just to identify key promoters in each population. Mixing cultured populations in a 3D model is something that I’m currently working on but currently not at the stage where we can assay inductiveness in vivo.

Maintaining the inductivity seems to go hand in hand with reducing the cells proliferation, when in a matrix/3D model the DP slow down their proliferation and this may have something to do with partially restoring their inductivity. Our current thinking is to rapidly expand the DP in culture then revert them to their inductive state. As to what will happen if we do get follicles successfully forming in vivo I’m not sure if they themselves will miniaturise over time, I think that’s a question for a later date.

Not sure on time courses for treatments, I can see things moving onwards but not sure what if any problems will arise over time.


Cheers,

Aaron Gardner

[hellouser]

I doubt many researchers are allowed to disclose anything of importance to the public. For instance, I emailed a guy involved in research related to the African Spiny mouse that's being studied because it can regenerate skin and hair. He didn't even respond to my email. I have also wondered why Aderans closed shop when eight years ago they had a very encouraging video. The video left me with the impression they had already achieved success and were simply only working out minor details.

I emailed Dr. Lauster a while back as have many others and never heard anything back. It's likely they just don't feel like answering all of our relatively petty questions when they've got bigger tasks to take care of.

[35YrsAfter]

Unless someone visits that university or writes a letter to one of those scientists, there won't be any news until the congress in May.

I doubt many researchers are allowed to disclose anything of importance to the public. For instance, I emailed a guy involved in research related to the African Spiny mouse that's being studied because it can regenerate skin and hair. He didn't even respond to my email. I have also wondered why Aderans closed shop when eight years ago they had a very encouraging video. The video left me with the impression they had already achieved success and were simply only working out minor details.

35YrsAfter also posts as CITNews and works at Dr. Cole's office
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Cole Hair Transplant
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email 35YrsAfter at chuck@forhair.com
The contents of my posts are my opinions and not medical advice
Please feel free to call or email me with any questions. Ask for Chuck

[Arashi]

Unless someone visits that university or writes a letter to one of those scientists, there won't be any news until the congress in May.

And unless we have somebody present at the conference, we wont wont hear anything in May (nor in the months following May) neither.

[ytterligare]

Unless someone visits that university or writes a letter to one of those scientists, there won't be any news until the congress in May.