So how close are we to a new 'cure'

[KO1]

If anybody is interested in learning about Follica and has a lot of free time:

http://www.sumobrain.com/patents/wipo/Intermittent-pulse-lithium-treatments-modulating/WO2011031990.html

[FearTheLoss]

Does the wounding leave scars?

no it's not that intensive...it's like sandpapering your skin almost, except with a device that is more precise.

[hellouser]

Does the wounding leave scars?

[KO1]

I know very little about Follica, but it sounds like their technique for regrowing hair is/was a lot more mundane than anything involving cutting-edge developments with growth factors, dermal papilla, stem cells, etc...

Indeed. Their basic idea is - wounding via dermabrasion/something else + topical. It is either very mundane and simplistic or very creative and elegant, depending on how effective it is.

[Dasani]

this is an insult to a lot of guys on this forum. myself included. i'd appreciate it if you just wouldn't speak on stuff you clearly know little about.

No I agree with him. I've coming up on year 2 anniversary of starting Finasteride. It changed my life. I was thinning, now I don't feel like I'm thinning anymore. And I've had 0 side effects.

[Pentarou]

I know very little about Follica, but it sounds like their technique for regrowing hair is/was a lot more mundane than anything involving cutting-edge developments with growth factors, dermal papilla, stem cells, etc...

[KO1]

You were simply stating that Follica has not even completed P1, I pointed out that's not true. That's all. Now certainly, you may be referring only to FGF9 treatments, but they may not even try FGF9. Frankly, I don't think the FGF9 discovery is really that important yet.


FYI, Follica will likely not need a Phase I trial for their process. I suspect it will be P2 or further. They already completed a first in man trial years ago, and if they play with well known compounds, safety has already been proven.

[Arashi]

Nah, that trial was regarding lithium gluconate gel, not FGF9.

[Arashi]

www.clinicaltrialsregister.eu

Nice find But is this trial https://www.clinicaltrialsregister.e...?query=follica regarding FGF9 ???

[Arashi]

So dam negative. Who the hell knows what follica is up too. They have been around a long time so they might shock us.

If you think I'm negative you've misread my postings in this thread. I'm very optimistic ! The first IPS cell trial OK-ed by Japan, Japan fasttracking stem cell research, Jahoda bio-engineering and growing human hair follicle on human skin and development of inner ear (including hairs) as a result of 3d culturing (which really seems to have been the missing link) is a reason to be VERY optimistic about the future ! And Dr Nigams is going to experiment with 3d culture soon, on forum member Tom, who knows, it just might work !!

[KO1]

Where can we read about that ? There's nothing on clinicaltrials.gov. Furthermore in the recent publication they only seem to talk about mice (http://www.sciencedaily.com/releases...0602144327.htm) . Hence it really seems they haven't tested it on humans. Furthermore it seems there are lot of "if's". Quite a few growth factors are associated with hair growth and FGF9 might actually be quite interesting but I highly doubt a single growth factor will grow hair on a bald scalp. Follica seems to be doing interesting work, but I really doubt they're going to bring us THE cure everybody is waiting for ...

https://www.clinicaltrialsregister.eu

[john2399]

Where can we read about that ? There's nothing on clinicaltrials.gov. Furthermore in the recent publication they only seem to talk about mice (http://www.sciencedaily.com/releases...0602144327.htm) . Hence it really seems they haven't tested it on humans. Furthermore it seems there are lot of "if's". Quite a few growth factors are associated with hair growth and FGF9 might actually be quite interesting but I highly doubt a single growth factor will grow hair on a bald scalp. Follica seems to be doing interesting work, but I really doubt they're going to bring us THE cure everybody is waiting for ...

So dam negative. Who the hell knows what follica is up too. They have been around a long time so they might shock us.

[Arashi]

Even if you search the DB for FGF9, it finds nothing. I'm pretty sure every FDA approved trial appears in that DB.

[Arashi]

Not true. Follica has finished a Phase 2 trial two years ago.

Where can we read about that ? There's nothing on clinicaltrials.gov. Furthermore in the recent publication they only seem to talk about mice (http://www.sciencedaily.com/releases...0602144327.htm) . Hence it really seems they haven't tested it on humans. Furthermore it seems there are lot of "if's". Quite a few growth factors are associated with hair growth and FGF9 might actually be quite interesting but I highly doubt a single growth factor will grow hair on a bald scalp. Follica seems to be doing interesting work, but I really doubt they're going to bring us THE cure everybody is waiting for ...

[KO1]

You agree that Follica hasn't even started Phase I ?

Not true. Follica has finished a Phase 2 trial two years ago.