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Also, it would be best if you would shave the whole recipient area but I don't think Tom is open to that ? It's going to make it a bit hard this way to monitor recipient growth. -
Dr Nigam,
The important ones are the macro ones. However they're not good enough in my opinion. It's really hard to see if donor grafts are 1's 2's or 3's.
What I'd suggest is to split up the donor area in 4 pieces and get a bit closer with the camera to each of those four pieces. Preferably shots in higher resolution too, if possible.
Also, is that area really big enough to get 2000 grafts ?Leave a comment:
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Tom' Before Procedure Macro Pics
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Dear friends,
We took Pre Op pictures of Tom vercetti today afternoon.
We will start the procedure tomorrow.
Kindly have a look at Pre Op pictures micro and video scope pics.
If anyone recommend any additional pics please let me know tonight, so that I can take the same so that my photographer can take photos tomorrow.
Enlarge video pic is slightly Blurred and will take again tomorrow final hairline measurement and drawing and hair distribution angles and phasing pattern for natural looking will be created tomorrow in house artist.
I told Tom that he does not need any procedure but he insisted he wants to work on his hairline. He says he is different and he wants to do what makes him happy. we took the pictures of Cristiano Ronaldo (photograph) from left view, right view, front view. Cristiano Ronaldo hairline is little different. I am trying to convince Tom not to lower the hairline beyond I hope I can convince him tomorrow.
Tom has his father with receding hairline (NW 3). Tom is 26 yr old not on any medication except few natural supplements, no finax no minoxidil. Does not seem to have MPB except little at the hairline as of now.
TREATMENT AIM AS PER PATIENT'S DESIRE.
1. Slight lowering of Hairline, Filling of Buff Temples in the Curve shave rather than in a zip form, special horizontal drop from the apex of angle of temple straight downward to the lateral temporal hair out growth as a style requirement.
2. Patient wants to save the donor hence prefer donor doubling and FUE.
3. Patient wants to inject Stem cells and DP cell injection for thickness of the whole scalp hair follicles.
PATIENT HISTORY OF HAIR TRANSPLANT
Patient has done Approximately of 1000 grafts by FUE on his hairline one year back at Belgium, But he says there is no proper growth after the previous procedure.
This is the protocol I plan to do for it.
1. In vitro donor Doubling
2. Activate Stem Cell Injection
3. Multiplied stem cell injection in August when he returns.
4. DP cell injections
5. Extra cellular matrix injection, advanced PRP
6. Hairline design as per patient requirement with touch up hairline for density next visit in August.
7. 2D DP culture injection in August when he returns.
From the video scope pic we will give number to every grafts and mentioned whether it is single, double or triple follicle graft and then subsequently monitor donor re generation by mapping. I will also let u know the distance of first and second horizontal Bun (Shave Stripe) distance from vertex and left ear tip of the lobule for tracking once the hair grow.
He will be going back Wednesday night, so that we can take pictures of Day 0 Day 1 and Day 2
Small Hair visible in video scope pics are of of stripe 1 (1 to 8 pics starting from left to right, margin of 5cm from the donor scalp hairline edge on both sides ) stripe 2 (1 to 8 pics starting from left to right, margin of 4cm from the donor scalp hairline edge)
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Veca,
Yes ,the future MPB cure hopefully will be with Cellular hair implants(HM).
Hair doubling/donor doubling is an improved version of HT.
Initially,HM will start as an adjunct to traditional HT.
And it's success rate improves..it should replace traditional HT/doubling.
By this year end..i will come to know..what trichogenic DP 3d spheroidal culture addition to autologous solution have in store for us...regards improvement in results of HM.
I do not think it is too far...specially if aderans and others..look for countries..with little relaxed relaxation..and counties which can accept their earlier trials...i am also searching for few such counties...
We lack a bossiness stalwart in MPB industry...who could have convinced the owner of a small island ,who would have created a special stemcell research zone..with same safety approvals...but also research friendly....
Another possibilty is... the moment any other disease gets a FDA clearance for treatment with autologous adult stemcell injections..The same can be used as off the label for injections of autologous adult stemcells of the hair follicle.
Since last few decades..it is the bone marrow stemcells..which are cleared by FDA..to use as therapy for leukemia..Hence prp (platelet rich plasma..with growth factors and a very small percentage of mesenchymal stemcells) is used as off the label for MPB/antiagieng/wound healing...And fortunately..use of bone marrow mesenchymal stemcells on humans.. have not had any significant side effects..is a good news for potential other stemcell therapies to come...
By Veca..And one more question: Do you think that the future is HAIR multiplication instead of traditional transplantation and Hair Dou-bling? And according to your estimates when it will become a standard?[/QUOTE]Leave a comment:
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Hello everyone,
being the creator and current co-administrator of the quoted french forum, I must state that "Tom" is not a moderator on it.
He used to be in charge (as co-moderator) of the "natural treatments" section on what is now the archived version of our forum. He did post 72 messages with that account, and you should find proof of that by googling "hairlossforum + mannolo13".
On the new version of our forum, launched somewhere around Feb 2012, I can't remember him participating at all.
Calling him "the french moderator" or "the coordinator of a french forum" is therefore inaccurate.
That being said, I remember "Tom" from another french-speaking forum, as far back as 2006 (when I personally started to contribute to the said board). So he is a legit patient, and that's what matters the most.
I wish him good luck and I hope he will actively publish his progress here or on another popular website.Leave a comment:
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Well, I wish you good luck tomorrow with Tom Vercetti. Let's stay positive and maybe all the members of the forum one day (hopefully this year or early next) meet in Mumbai at Dr. Nigam. ;-)Leave a comment:
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5000 doubling to 10000 grafts patient should visit me..anytime mid june..spoke to him today..he is also a HT doc..busy with his practice...
I did start the process of another nw7 to nw2 on a patient from USA..he posted his pics..but without videoscopic pics..and clear macro pics by him.. i can't document..he will be coming for his 2nd procedure..after 1 to 2 months for his HM injection and further doubling...
Tomorrow will be the second day..of another nw7 to nw2..i will show him to Tom Vercitti...as we might start Tom's case tmr itself..he arrived tonight to mumbai..sent the clinic car to pick him up from the airport..also spoke to TOM on phone..tonight
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And one more question: Do you think that the future is HAIR multiplication instead of traditional transplantation and Hair Dou-bling? And according to your estimates when it will become a standard?Leave a comment:
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Dr. Nigam,
Thank you for your response, I hope good results with Tom V. case. I hope you will soon post pictures of the case, "5000 G to 10000G" doctor from India, it's been two months. However, we all would like to see another classic example NW7 turn in NW2. Do you plan to do that?Leave a comment:
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didi,
It's better to share donor doubling..anyway..a smart surgeon can pick up the technique of donor doubling,as we have discussed extensively and openly..as i said earlier..many docs will perform doubling shortly..especially the enterprising one..
I do not believe in patent/ keeping to oneself and not sharing or partnering...especially in the field of medicine..I am in discussion with few surgeons...
Whatever ..i am able to do..is only because others shared with me... their research..
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Veca,
I think you would agree,that donor doubling is as safe as fue,till i do not add anything further..
Now what i add further and let us see where do i stand on safety quotient..
1)We add stemcell injection to the implanted grafts on day0.
Activated or progenitor stemcells are derived by activating the quiescent stemcells present right now inside your follicles,helping it repair when required plus used in wound healing ..
Activated progenitor stemcells from multipotent autologous source are not multiplied yet..hence still safe without doubt..can google and confirm...
We isolate dp cells from few follicles from scalp or body. and inject into bisected follilces when implanted.
Now this should not have any safety issue, as no non autologous additions yet..
Than comes,the additions of multiplied stemcells inj given after 6 weeks..this is optional for the doubling patients..they have to decide.. that the available safety data is sufficient from them or not...
The autologous stemcell solution of multiplied stemcells,are tested for any mutations before being injected on the scalp...we have not found any sample with mutation till now...can google and confirm from studies till how many passages are multipotent autologous follicle stemcells considered safe..
Licensed physician,from our clinic to our patients, for specific medical condition can compound and dispense..combination of ingredients ,which are sourced from FDA cleared manufacturers or distributors...
Our lab is FDA licensed.OBI posted the pics of our license.
All the products used in the lab are sourced from FDA licensed manufacturers or distributors from india or from international biotech companies based in india ....which have their products cleared from FDA for sale to the biotech labs.
Regards growth factor..which is again optional for use by the patient,
I am researching on them...closely watching histogen and another companies clinical data on safety...histogen as FDA clearance for safety with certain growth factors used by them with their 1st phase of clinical trials.
This is another step forward...
I am not using wnt7a , as of know..although it is an important ..protien in potential hair regeneration...
Another way to crete safe growth factors is auotologous, as against allogenic of histogen..by dp culture..wherein it secretes ecm with growth factors in culture ...
For any new evolving science...or therapy...100% safety..will be assured even by FDA..only as time passes..and if something is found unsafe ..after FDAa clearence..it withdraws it...
With brochure of every medicine , cleared by FDA..it mentions potential adverse effects...
I offer this as new medical procedure ..not as new product..like histogen/aderans..which requires clinical trials and approvals and can be sold in mass market ...we can offer new medical procedure(not product) only from our clinic..to our patients, for their specific medical condition ,with a consent form detailing all pros and possible side effects.We need to maintain all records of this new therapy..
Still better,submitting USA ..FDA safety clearance of similar process ..and documents supporting our claim from leading published papers..
Than , we are registered with Independent Institutional commitee for stemcell research and Independent institutional ethics commitee for stemcell research.
Another way to look at safety is ..the clearance by FDA, for safety of multiplied stemcells injection in their clinical 1st phase trials for safety of aderans...intercystix(now bought by aderans)..as they have safety clearence by FDA..now they move to their next phase of clinical trials...
Oldest(10years back) to have taken such injections would be from intercystix clinical trial..which have not shown in any side effect as per aderans data..or else FDA would have withdrawn permission to them for next stage of clinical trials...
So autologous stemcell injection a it does not require differentiation and/or major manipulation is safe..especially if every sample is checked for ruling out any mutation...
FDA..has it's oldest stemcell clearance of bone derived stemcells and injections..many years back..and it's fda approval still holds..or else it would have been withdrawn...
ACELL had been used at clinics in USA,UK... by physicians..to their patients..although it is cleared by FDA,USA for wound healing..and not for hair regeneration...this is allowed..called off label use of a product by the physicians...
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