7th World Congress for Hair Research (2013)

[drnigams]

Arashi,
Believe me, i am not talking about nano particulate delivery alone..but also iontophoresis and other mechanism of skin permeation to deliver and keep local concentrations of finasteride at the scalp...yes nano particulate will take time for it's biodegradable factor and permeation beyond into the tissues of dermis...

As always, you're exaggerating things. Sure, nanoparticle assisted drug delivery is going to be one of the biggest pharma breakthroughs of this decennium but not 'soon' as in next year. Very interesting progress is currently being made, one of the biggest concerns of course was the toxicity of the particles, so bio-degradability is key and just yesterday this awesome news came out: http://www.sciencedaily.com/releases...0507115506.htm however research here is still pre-clinical. By the time nano particle assisted drug delivery is a main stream thing, we'll hopefully have a real cure like Team Tokyo's available as well.

[Arashi]

The nanotech you're thinking of is the Star Trek whacko science.

The nanotech these biotechnology professionals are talking about are the same technology they currently use in a number of skin creams such as most famously sun lotion which reduces systemic absorbtion/side effects.

What do you mean ? The nano particles guide drug to a specific target and degrade there, releasing their load (fina in this case), to lower side effects of the drug. Not sure what you mean ?

[Arashi]

Arashi,
Believe me, i am not talking about nano particulate delivery alone..but also iontophoresis and other mechanism of skin permeation to deliver and keep local concentrations of finasteride at the scalp...yes nano particulate will take time for it's biodegradable factor and permeation beyond into the tissues of dermis...

Ok. Anyway thanks for sharing info from the conference here, that's much appreciated and certainly nice to see you do that.

[UK_]

What do you mean ? The nano particles guide drug to a specific target and degrade there, releasing their load (fina in this case), to lower side effects of the drug. Not sure what you mean ?

You're talking about a completely different strand of nanotechnology - clearly you dont understand the difference, I'm not expecting someone to inject me with finasteride and then have it delivered by a microscopic robot as a payload to each of my hair follicles. Jesus Christ.

[Arashi]

You're talking about a completely different strand of nanotechnology - clearly you dont understand the difference, I'm not expecting someone who inject me with finasteride and then have it delivered by a microscopic robot as a payload to each of my hair follicles. Jesus Christ.

I think you're confusing stuff. Nanoparticles are not robots. They're just a 'vehicle' that can bind to a certain target.

[Arashi]

You're talking about a completely different strand of nanotechnology - clearly you dont understand the difference, I'm not expecting someone to inject me with finasteride and then have it delivered by a microscopic robot as a payload to each of my hair follicles. Jesus Christ.

Here is an interesting article that explains how it works and what nanoparticles are: http://www.medscape.com/viewarticle/770397

As you'll see, nanoparticles are not robots, but just 'structures' that can bind to a target. Also read page 5 to understand why it will take years before this will be approved and used for cosmetic drugs like fina (in summary, safety concerns + high costs)

[Jairus]

Well? Does anybody know when the Histogen updates are available??

[Pentarou]

Pentarou,
1)The swiis/japanese company product manager approached me for mini clinical trial of their topical CG210 alone or in conjunction with oral or topical finasteride foam.They provided me with few samples.
Can only tell about it's efficacy after using the same.
2)P-3074 a topical 0.25%finasteride with special delivery vehicle called HYDROXYPROPYL CHITOSAN(HPCH),a film forming agent,with single daily topical dosage showed reduction in scalpDHT by 71.2% as against oral finasteride which showed reduction of scalp DHT by 51.1% with equal period of therapy.
With Annika Vogt coming up with nano particulate and virus like targetted delivery vehicles(to every aspect of follicle ,including stemcells)..oral finasteride will be in the grave yard soon..and it's systemic sexual side effects could be avoided.

Thank you, Dr Nigam!

[Conpecia]

Thank you, Dr Nigam!

Yep. This is the best news out of everything. Just need to know if it affects estrogen levels.

Topical Fin + Minox = maintenance until Histogen!! So pumped!

Topical Fin + Minox + Rahal HT = NW1!!! (assuming you're NW3 or lower)

[ovoxo]

the question is when this topical finasteride will be released...

[Thinning87]

Well? Does anybody know when the Histogen updates are available??

That's a great question! And does anyone know when the cure for hair loss will be found? I want a precise date and time

[MrBlonde]

the question is when this topical finasteride will be released...

Minimum of two years I would imagine

[john2399]

Minimum of two years I would imagine

Why 2 years? Finasteride is already approved by the FDA. They would just have to do a 1 year trial on efficacy.

[UK_]

I wouldnt be surprised if its fcuking "5 years away"!

[Conpecia]

Why 2 years? Finasteride is already approved by the FDA. They would just have to do a 1 year trial on efficacy.

If that. We could reconstruct the vehicle and get it on the black market in 6 months unless it's something very protected or very difficult.