7th World Congress for Hair Research (2013)

[hellouser]

Even with your own cells, there can be issues with implanting them. Particularly if they are stem cells, as they are totipotent (able to differentiate into any types of cell) or pluripotent (able to differentiate into many types of cells). Given that they have this totipotency, f they receive the wrong "messages" (as it were) from the body, then there is a very large breadth of tissue types they could develop into. Ones which you would obviously not want in your scalp.

There could also be an issue with stem cells that refuse to die - think cancer.

So there is a high chance they would have to start again. Or maybe start running this trial parallel to their current one, and almost release it as an "update" in the future. Hair v1.1.

I was thinking this too. If they released their current method as a treatment now, I'd definitely go for it, and go for another treatment with their update.

[UK Boy]

I'm not so sure they would have to start from scratch again. If you read the Replicel thread you will see that they have changed their cell culturing protocol from phase I but they're still moving into phase II not doing a new phase I. Maybe Aderans would have to do phase II again with the new spherical culturing but it'd be a much shorter phase II cos they hopefully now know which is the best version of Ji Gami. I dunno I'm sure there'll be some reason or other why it'll take years but if Replicel can change culturing protocol without starting over I'm sure Aderans should be able too. Unless it's cos FDA are stricter than the Germans.

[hellouser]

I'm not so sure they would have to start from scratch again. If you read the Replicel thread you will see that they have changed their cell culturing protocol from phase I but they're still moving into phase II not doing a new phase I. Maybe Aderans would have to do phase II again with the new spherical culturing but it'd be a much shorter phase II cos they hopefully now know which is the best version of Ji Gami. I dunno I'm sure there'll be some reason or other why it'll take years but if Replicel can change culturing protocol without starting over I'm sure Aderans should be able too. Unless it's cos FDA are stricter than the Germans.

why the hell did aderans chose USA and the FDA to run through with their clinical trials? All its done is give them a shitload of hoops to jump through.

[FearTheLoss]

why the hell did aderans chose USA and the FDA to run through with their clinical trials? All its done is give them a shitload of hoops to jump through.

So they can release it directly after trials I would assume...

[Thinning87]

So they can release it directly after trials I would assume...

There's a billion reasons why a company would want to do R&D in the US I think the most relevant here is knowing that whatever they come up with they can patent in a country where the rule of law is actually enforced, not to mention the fact that if you hire someone and then want to fire them there is no BS laws or constitutional clause making you potentially liable for a lawsuit (think France, Italy, Spain, Greece, etc. - no offense to our European friends...).

Ultimately the US is still the most business friendly place on earth, with maybe a few exceptions like countries like Singapore which are stil obviously not the potential market the US can be.

[john2399]

Anyone know when they talking about histogen and aderans at the congress?

[Thinning87]

and why does Histogen think the congress is on May 8th lol hopefully they got their dates right and they will show up when it is their turn to speak and not 3 days later haha!

[john2399]

and why does Histogen think the congress is on May 8th lol hopefully they got their dates right and they will show up when it is their turn to speak and not 3 days later haha!

that would suckkk lol

[garethbale]

and why does Histogen think the congress is on May 8th lol hopefully they got their dates right and they will show up when it is their turn to speak and not 3 days later haha!

Oh great, they'll turn up on the 8th, nobody will be there, and their treatment will be set back another two years...

[Thinning87]

haha! No... they are going to the "Investigative dermatology conference" or something like that, whereas what's happening until the 7th is strictly hair. Two similar events consecutively in the same location... hopefully lots of people will be working up their network, share, and develop new ides...

Anyways Aderans is actually presenting tomorrow morning. Seems like we have no way of knowing what they'll say though right?

[garethbale]

haha! No... they are going to the "Investigative dermatology conference" or something like that, whereas what's happening until the 7th is strictly hair. Two similar events consecutively in the same location... hopefully lots of people will be working up their network, share, and develop new ides...

Anyways Aderans is actually presenting tomorrow morning. Seems like we have no way of knowing what they'll say though right?

I am sure if you email the organisers they will provide you with a report of the conference...what was said etc.

I can't believe that there would be no record of this and I'm sure it would be publicly available

[UK_]

This is all great Desmond but how long will it realistically be before anything comes of this? It all seems so easy, Jahoda just needs to speak to the Scots, Aderans needs to speak to Jahoda and then Aderans should use this spheroid culturing technique in the phase III trials. The meeting this week is the perfect opportunity for these guys to get together, I wish that they use it to everyone's advantage and don't just waste it.

This is the thing, all of these great new discoveries in University labs are all well and good, but they will all need to go through a process of clinical trial and then become marketable products which could take in total more than a decade.

(Havent Wake Forest been printing organs for the past 7 years?, It's nothing new!)

This is why the cure for hair loss is always "5 years away", every year we hear about these supernatural discoveries in labs somewhere and then nothing comes of it, or something happens that takes forever to bring to market (bear in mind NOTHING new has come to the market since the 1980's!!!!).

This hair loss convention seems more like groups of scientists getting together and talking about whacko science that is probably 50+ years away from being on the shelf - mostly mental masturbation.

I'm seriously not impressed, all we need to know is an update from Aderans and Histogen, **** everything else.

[Pentarou]

I agree with UK_.

[Desmond84]

OK guys, up until today the only treatments that have been available were only through serendipity (i.e. Minoxidil) or hairloss scientists actually working actively towards a solution to AGA (i.e. Propecia, Histogen, Aderans, Replicel, etc)

Now, here's one factor you're not taking into account! Regenerative medicine has changed the game altogether! You have scientists ALL over the WORLD working on ways to regenerate organs! Lack of funding for hairloss is no longer relevant!

We have labs multiplying stem cells, printing them in 3D, implanting them, conducting long term trials on them ALL ACROSS THE WORLD! I would guess there are over 20,000 scientists working on these breakthroughs!

Once, we can generate one organ we can generate most of them...albeit some may be more difficult (e.g. liver)...

We will be able to regenerate many organs in the next 10 years and hair follicles will most definitely be up there in that list!

So, plz don't underestimate these breakthroughs! Everyone of these findigns is relevant to us in ways you can not imagine!

Keep it together guys...Love you all

-Des

[Breaking Bald]

+1 Totally agree, great post Desmond!! Everyone needs to cheer up a little, stop moaning and arguing.