Histogen at the ISHRS conference

[rdawg]

this thread is such a rollercoaster between soon having a cure and to everything is hopeless. As far I'm concerned, Aderans and Replicel are finished. Don't expect anything from them. They don't have anything now nor will they have anything in the future.
desmond was right when he said that those were our only hopes in the next 10+ years. Take away those two, and you're only left with Histogen who has shown poor results at this point however you want to spin it. They had more than 5 years to figure out this crap and up to this point they got nothing.

also, to the person who thinks that "regrowing" follicles is as difficult as regrowing heart then wow he doesn't know jack and judging how Aderans and Replicel describe their "science" they don't know it either. Follicles "regenerate" with each cycle automatically. Anagen -> Miniaturized follicle -> Anagen again. The problem is with activation and missing growth factors required to grow visible/normal hair.

This is an extremely baseless comment.

I dont know how you go from being a normal poster to an extreme pessimist for no reason? You are all over the place with your theories and beliefs.

How has histogen's results indicated that they have nothing? so far it's indicated quite the opposite.

Just give them some time before you start shouting the apoloclypse. Hell we'll have another update within a few months.

The way I see it and this isn't trying to be super optimistic. Histogen injected a small area, got solid results(as in somewhat noticeable, the pictures definitely showed at least minor growth, IMO a couple patients had very noticeable growth) and will now inject MORE people, with more injections in a bigger area more frequently, in an attempt to get even better results.

The pictures do need some work and they need to fix that problem(lighting and such), but there's only been an indication of a great product so far, nothing to the contrary IMO.

[rdawg]

another thing that concerns me:



You can find this comment here:

http://forum.hishairclinic.com/topic/if-you-are-also-interested-in-histogen-read-here#.UNiUaG9J6dw

I also asked a dermatologist about histogen, and he said to me that a trial like that have to contain more participants. (300 people at least!!)

Histogen did phase 1 with 20 people and phase 2 with 50 people..
:S

Fair enough to have the concern, but nothing indicates histogen is dangerous at all, so I wouldn't really go into it thinking it's harmful as of right now.

Plus there's about 2-3 years of tests left, we'll know by then. That fen product had the FDA split due to them wanting hypertension warnings on that drug.

no idea how many will be in the next trial(or specifically when Phase IIb will start)

phase III is usually the big trial though with hundreds of people testing it.

[koolx]

Secondly, koolx I've attached a copy of the trial in the link below for you to look at. I think your confusion comes from the fact that you're not aware of the number of injections they used. This was merely a safety trial (Phase I/IIa). So they only injected each patient with 8 injections at 3mm apart. Now, in order for you to notice significant cosmetic growth on the top of your scalp, they need to inject 200-300 injections!

Now I promise you they will eventually reach a point where they will inject the whole scalp (Phase IIb) and by the look of things, the results will be impressive. Just be patient and don't attack anyone on the forum! We're all here to help each other get through this curse

http://clinicaltrials.gov/ct2/show/N...istogen&rank=1

thank u desmond.. i'll be reading that link soon. and i appreciate the follow up. hopefully this is encouraging news. and i only attack those who attack me.. thats my M.O.

... This is where I tell you to f*** off and die like all the other sceptics and whiney little bitches.

As punishment I hope that when Histogen does come out and does work that people like you wont be able to afford it.

and this is the part where i tell u that u get NO P'USSY.. thats why u sound so sexually frustrated cuz women see ur bald spot and run. and as a result u turn to men. thats why u sound so defensive like an old fa'g.

as punishment i hope when histogen comes out that it doesnt work on u cuz ur balding area is TOO large for it to help u.

ur out of luck rupaul.

[bananana]

ffs!

this sounds like a kindergarten!
How old are you all? Stop with insults will you?

Jesus, there cant be a single page on a single thread here without balding guys bashing on other balding guys. Pathetic.

We're in this all together. Be productive for a change.

[Breaking Bald]

ffs!

this sounds like a kindergarten!
How old are you all? Stop with insults will you?

Jesus, there cant be a single page on a single thread here without balding guys bashing on other balding guys. Pathetic.

We're in this all together. Be productive for a change.

+1 The insults and comments are childish and ridiculous!

[Dan26]

It's all about growth factors my balding brothers. If Histogen was going HAM with their injections (aka higher dose/frequency) AND using an AA, believe me results would be legit. Growth factors are thee big pieces of the puzzle.

[clandestine]

It's fine; let's them vent amongst themselves.

[koolx]

It's all about growth factors my balding brothers. If Histogen was going HAM with their injections (aka higher dose/frequency) AND using an AA, believe me results would be legit. Growth factors are thee big pieces of the puzzle.

but havent other studies used growth factors to stimulate hair growth?

[yeahyeahyeah]

You guys need to get off these forums, and live your life.

No amount of over analysing bullshit is going to a) give answers and b) speed of the process.

Whereas, for all of you, your life is ticking away as we speak.

Say you get a full head of hair at 30 plus, if you haven't got a career you are ****ed anyway.

Life is too short.

[koolx]

Say you get a full head of hair at 30 plus, if you haven't got a career you are ****ed anyway.

Life is too short.

i agree with that.. but there are many guys out there who find confidence with their hair. and they miss the opportunities associated with what their hair used to give them when they had it. nobody wants to be bald, even if ur rich. persoanlly, i'd rather be poorer with a full head of hair than rich without my hair.

[yeahyeahyeah]

i agree with that.. but there are many guys out there who find confidence with their hair. and they miss the opportunities associated with what their hair used to give them when they had it. nobody wants to be bald, even if ur rich. persoanlly, i'd rather be poorer with a full head of hair than rich without my hair.

Yeah well - there is nothing we can do right now. And big corporate companies won't care that you under performed due to hairloss.

It's brutal out there.

[Pate]

I also asked a dermatologist about histogen, and he said to me that a trial like that have to contain more participants. (300 people at least!!)

Histogen did phase 1 with 20 people and phase 2 with 50 people..
:S

That's totally normal. It steps up with each phase. Phase III will have 300+ people.

[Pate]

about the photos thing,

Both Histogen and Zerinig showed us photos.
SID - they showed the "before after" photos from Ziering clinical trials - 3 months after injection in female patients in USA.

ISHRS - my questino is - what photos did they show us? from histogen or ziering trial?

Are there any photos from the trial in philippines???

The micro photos of buzzed hairs are from the Philippines trial.

The macro photos of long hair are from Ziering's trial.

I'm still not super impressed by any of Ziering's photographs except the one of the black woman's hairline (it's a woman, not a man). That's the only one that unambiguously shows new growth IMO. The others have issues with lighting and combovers.

But like I've said, it takes a long time for hair to grow in properly, at least 12 months. The micro photos of buzzed hairs definitely, clearly show new growth. Just not as much as I'd like.

I'm pretty confident that as long as it continues to be shown as safe, Histogen will have a marketable product at this level of efficacy. And it will be the single best marketable treatment for hair loss other than HTs.

[koolx]

But like I've said, it takes a long time for hair to grow in properly, at least 12 months. The micro photos of buzzed hairs definitely, clearly show new growth. Just not as much as I'd like.

I'm pretty confident that as long as it continues to be shown as safe, Histogen will have a marketable product at this level of efficacy. And it will be the single best marketable treatment for hair loss other than HTs.

when did the trials showing results of the pics begin?

and it would be something to combine histogen with stem cells.. that'd probly be something worth doing. or combining those 2 with HTs.

[Pate]

when did the trials showing results of the pics begin?

and it would be something to combine histogen with stem cells.. that'd probly be something worth doing. or combining those 2 with HTs.

The Phase II trial began in January 2012 so the 12 month results should be out in 3 months time or around then. I don't know when Ziering's trial began. Probably about the same time.

The micro photos of the buzzed hair were at 12 weeks.

The macro photos of Ziering's trials were 12 weeks, 19 weeks and 24 weeks from the first set of injections.

Ziering's trials had up to four sets of injections at 0, 6, 12 and 18 weeks. Leave them for 12 months and then have a look at the macro photos. If they don't have significant cosmetic hair growth by then, then the critics will be right.