Cetirizine

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  • Pate
    replied
    Originally posted by yeahyeahyeah
    So what happens if this ends up working?
    Depending on how well it works, then I will need to make a decision about whether to take the additional risk of chronic longtime use.

    But let's not count our chickens just yet.

    It would need to be at as good as what those others are seeing to convince me to keep using it. Moderate regrowth isn't worth it for me. But I will say one thing. This is easily the best regrowth I have ever seen on slick bald temples. If these initial indications prove accurate (massive IF) then it could be huge.

    I'm still sceptical. But if I see any regrowth at all it'll still be significant. This is not an ideal PGD2 inhibitor and it's not in an ideal vehicle, so any regrowth will be a big plus for future treatments going the PGD2 route.

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  • yeahyeahyeah
    replied
    Originally posted by mjolnir
    Looking at this perhaps a bit more pragmatically, do we know anything at all about how safe this stuff is in high concentrations when applied topically? As someone pointed out earlier, we do have the FDA for a reason.
    Well tbh I have a suspicion the FDA will intervene if say this stuff ends up working. Like they did with Dr Lee.

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  • yeahyeahyeah
    replied
    Originally posted by clandestine
    Uh, then it ends up working? Hair loss cured, etc, etc.
    Will be hilarious if the cure for hairloss is found by forumers.

    Leave a comment:


  • clandestine
    replied
    Originally posted by yeahyeahyeah
    So what happens if this ends up working?
    Uh, then it ends up working? Hair loss cured, etc, etc.

    Leave a comment:


  • yeahyeahyeah
    replied
    Originally posted by Pate
    No, we don't. However we do know it is a very safe drug and we are not applying it in any higher dose than people who take it orally - 10mg. I read up on the safety profile on Pfizer's website and it has proven safe in animals up to many times the standard dose. There were also reports of overdose in humans with no major effects, including an infant who took a staggering 180mg (equivalent to about 1300mg to an adult male!!!) with no major effects.

    Finally, I consider this at this stage a short term trial of about 6 months. So I am not worried about long term chronic use effects.

    But it is something everybody who is considering this absolutely MUST keep in mind. This usage of Zyrtec HAS NOT been confirmed as safe by regulatory bodies and we assume a certain degree of risk.
    So what happens if this ends up working?

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  • Pate
    replied
    No, we don't. However we do know it is a very safe drug and we are not applying it in any higher dose than people who take it orally - 10mg. I read up on the safety profile on Pfizer's website and it has proven safe in animals up to many times the standard dose. There were also reports of overdose in humans with no major effects, including an infant who took a staggering 180mg (equivalent to about 1300mg to an adult male!!!) with no major effects.

    Finally, I consider this at this stage a short term trial of about 6 months. So I am not worried about long term chronic use effects.

    But it is something everybody who is considering this absolutely MUST keep in mind. This usage of Zyrtec HAS NOT been confirmed as safe by regulatory bodies and we assume a certain degree of risk.

    Leave a comment:


  • mjolnir
    replied
    Looking at this perhaps a bit more pragmatically, do we know anything at all about how safe this stuff is in high concentrations when applied topically? As someone pointed out earlier, we do have the FDA for a reason.

    Leave a comment:


  • Conpecia
    replied
    Originally posted by Pate
    I'm going to start it this weekend.

    What is the point of adding PG? I've never been able to get a straight answer.

    I'm still finalising my method but for now I will be looking to apply about 10mg/day in distilled water only. I gave up minox about six months ago (and didn't notice any difference, which I guess shows what minox was achieving - f--k all!). The rest of my regimen is 1mg fin per day and 2% keto twice or three times a week.

    Conpecia, I am worried about the shed too, which is why I'm going to start on the slick bald areas of my temple and a small depth along the hairline. If there is no major shed, or if there is a shed that grows back noticeably stronger, I will gradually extend it along the rest of my thinning areas.
    I'm not sure about PG's function, but good to hear that you are going to give this a shot. I may follow your lead and just apply it to slick bald areas on the hairline first, gradually moving back if I get results. Please keep us updated, and good luck with this.

    Leave a comment:


  • The Alchemist
    replied
    Originally posted by Pate
    I'm going to start it this weekend.

    What is the point of adding PG? I've never been able to get a straight answer.

    I'm still finalising my method but for now I will be looking to apply about 10mg/day in distilled water only. I gave up minox about six months ago (and didn't notice any difference, which I guess shows what minox was achieving - f--k all!). The rest of my regimen is 1mg fin per day and 2% keto twice or three times a week.

    Conpecia, I am worried about the shed too, which is why I'm going to start on the slick bald areas of my temple and a small depth along the hairline. If there is no major shed, or if there is a shed that grows back noticeably stronger, I will gradually extend it along the rest of my thinning areas.
    PG is added to help with solubility. Because this compound is so water soluble, it may not be necessary. I added to mimic other topicals i've looked at. Ethanol is added too - will help with absorption.

    Tomorrow will be my 2 week mark on Cet. I've had some shedding during the first few weeks, for sure. But, other than that, no side effects to speak of. Can't say for sure, but, i think some of the vellus hairs i have near my hairline are getting much longer - almost as long as a normal hair. Not sure if they were like that before, but, i can't recall seeing anything like it. No sign of anything else - but it's very early on for me.

    Leave a comment:


  • Pate
    replied
    I'm going to start it this weekend.

    What is the point of adding PG? I've never been able to get a straight answer.

    I'm still finalising my method but for now I will be looking to apply about 10mg/day in distilled water only. I gave up minox about six months ago (and didn't notice any difference, which I guess shows what minox was achieving - f--k all!). The rest of my regimen is 1mg fin per day and 2% keto twice or three times a week.

    Conpecia, I am worried about the shed too, which is why I'm going to start on the slick bald areas of my temple and a small depth along the hairline. If there is no major shed, or if there is a shed that grows back noticeably stronger, I will gradually extend it along the rest of my thinning areas.

    Leave a comment:


  • Conpecia
    replied
    Originally posted by hellouser
    Can you post links or photos of these guys results? I'm particularly interested in the hairline results, that sounds... promising.
    http://www.****************/interact...chmentid=18765

    this is baldnesssadness at 2 months of cet. he is also on minox.

    Leave a comment:


  • hellouser
    replied
    Originally posted by Conpecia
    That being said, I keep hearing more and more good news about Cetirizine. Casperz from *** just updated again with photos documenting regrowth on an area that has been slick bald for TWENTY YEARS. He's got the pics. He reports hundreds of small, terminal black hairs popping up everywhere.

    Another user named baldnesssadness just put up a photo of 6 week results. THE GUY'S HAIRLINE IS GROWING BACK. VISIBLY. This user is also on minox I believe, and I'm not sure how long he's been taking that. But Pate mentioned that a minox/cet combo might be necessary and perhaps he's right.
    Can you post links or photos of these guys results? I'm particularly interested in the hairline results, that sounds... promising.

    Leave a comment:


  • Conpecia
    replied
    Ok guys, without firsthand knowledge of how this stuff is being used by the members of other forums, and without plenty of results to sift through, I'm still maintaining a healthy dose of skepticism.

    That being said, I keep hearing more and more good news about Cetirizine. Casperz from *** just updated again with photos documenting regrowth on an area that has been slick bald for TWENTY YEARS. He's got the pics. He reports hundreds of small, terminal black hairs popping up everywhere.

    Another user named baldnesssadness just put up a photo of 6 week results. THE GUY'S HAIRLINE IS GROWING BACK. VISIBLY. This user is also on minox I believe, and I'm not sure how long he's been taking that. But Pate mentioned that a minox/cet combo might be necessary and perhaps he's right.

    A third user, Hairoutthewazoo, just reported one month results of seeing lots of vellus hairs cropping up after an intense shed.

    .......I'm not really sure how to react to all of this. Part of me is absolutely blown away by some of these photos, and of course there's that little voice in my head saying "this could be something huge." But I've been around the block a few times with these new treatments and the last thing I want to do is hype everybody up just to find out that, for whatever reason, it doesn't work out as far as regrowth or prevention. So here's my take on it: It's still TOO EARLY to make a judgment on the real efficacy of this treatment. We're getting excellent reports and seeing some very positive photographs, but we have to be patient before we can start popping the champagne.

    My main fear is that I undergo a severe shed and don't regain anything worthwhile; that would crush me. I'm sticking to my guns and waiting at least until December to get going with Cet. Hopefully more good news will be coming our way from these other guys.

    A lot of people wrap things up with "stay positive." My advice is to stay skeptical; let's manage expectations for a few more months and if we keep getting good news, then we can let our guards down a bit.

    Leave a comment:


  • hellouser
    replied
    Originally posted by thechamp
    Where you buy propylene glycol from?
    I bought some at my pharmacy. Just straight up asked 'Can I get some PG, about 200ml worth?'

    They charged me $3.10.

    Leave a comment:


  • doke
    replied
    Hi champ got 200mls which i think will last a fair while at http://www.aromantic.co.uk i am not sure if this link will work?

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