If it were PGD2.....

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  • 2020
    replied
    Originally posted by gutted
    Your saying that because histogen supplied the initial growth factors for the hairs to regrow/regenerate then we would need to continuously supply the hairs with those histogen growth factors for it to regenerate again?
    yes, because your body provides those growth factors naturally before hair enters anagen phase. For bald people that doesn't happen and that's why those hairs stay permanently in telogen phase.

    Histogen CAN provide those growth factors to artificially simulate another anagen phase for you, but after that phase is over your body couldn't reproduce those growth factors again for another phase so you would need Histogen growth factors again....

    Histogen == +1 extra hair cycle which actually sucks really bad I'm not sure if they know it themselves

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  • gutted
    replied
    Originally posted by 2020
    exactly why the **** didn't Spencer ask this question during their 40 minute interview:

    what makes you think a follicle will start a second cycle after growth factors for the first cycle stop working?

    I changed my position from optimistic to we're all ****ed...
    i think i know what you are trying to say with histogen.

    Your saying that because histogen supplied the initial growth factors for the hairs to regrow/regenerate then we would need to continuously supply the hairs with those histogen growth factors for it to regenerate again?

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  • gutted
    replied
    Originally posted by 2020
    right, so I'm guessing 100% of people didn't know that actual follicle size changes from cycle to cycle... that makes Histogen and all other stimulants useless

    http://www.hairdoc.com/book/Chapter_...ss_answers.pdf
    dude you are misinterpreting what they are saying.

    They miean minuturisation as the follcile starts to stop production and begins to "regress" or "minuturise".

    When its time to regenerate during early anagen the hair follcile begins to grow back to normal size but in mpb individuals the size of the follicle develops/regenerates partially minuturised and not to full size.

    histogen will last a decent length of time if inflamation is addressed. If not it will last probably 2/3 hair cycles, until it becomes dormant again.

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  • neversaynever
    replied
    Nice interview with Dr Cots....

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  • neversaynever
    replied
    Originally posted by neversaynever
    But that doesnt deal with the fact there is excessive PGD2 around balding follicles. So maybe itll help early to moderate baldness. In which case, discussions should halt until people start trying it.

    There is too much missing pieces to know how long HSC would last. Too be honest, if the price is right, if one HSC treatment buys you at least 2 years...id be happy.

    And they are getting great results, better than anything we've ever seen in hair loss treatments, so I find it hard to be negative about them.
    Unless maybe its that binding to the receptor that causes the malfunction, and pgd2 is over expressed? That would indicate that blocking this receptor is the key!

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  • neversaynever
    replied
    Originally posted by Ryan333
    I don't think it's a question of blocking PGD2 completely, it's about stopping it binding to a certain receptor, the receptor that OC000459 targets, so you won't be affecting its positive effects on hair cycling.
    But that doesnt deal with the fact there is excessive PGD2 around balding follicles. So maybe itll help early to moderate baldness. In which case, discussions should halt until people start trying it.

    There is too much missing pieces to know how long HSC would last. Too be honest, if the price is right, if one HSC treatment buys you at least 2 years...id be happy.

    And they are getting great results, better than anything we've ever seen in hair loss treatments, so I find it hard to be negative about them.

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  • Ryan333
    replied
    I don't think it's a question of blocking PGD2 completely, it's about stopping it binding to a certain receptor, the receptor that OC000459 targets, so you won't be affecting its positive effects on hair cycling.

    Leave a comment:


  • Hairismylife
    replied
    Originally posted by 2020
    exactly why the **** didn't Spencer ask this question during their 40 minute interview:

    what makes you think a follicle will start a second cycle after growth factors for the first cycle stop working?

    I changed my position from optimistic to we're all ****ed...
    Aderans still here

    Leave a comment:


  • ccmethinning
    replied
    Originally posted by 2020
    exactly why the **** didn't Spencer ask this question during their 40 minute interview:

    what makes you think a follicle will start a second cycle after growth factors for the first cycle stop working?

    I changed my position from optimistic to we're all ****ed...
    There's still Gho.

    Leave a comment:


  • 2020
    replied
    Originally posted by ccmethinning
    The histogen charade is over
    exactly why the **** didn't Spencer ask this question during their 40 minute interview:

    what makes you think a follicle will start a second cycle after growth factors for the first cycle stop working?

    I changed my position from optimistic to we're all ****ed...

    Leave a comment:


  • ccmethinning
    replied
    The histogen charade is over

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  • 2020
    replied
    Originally posted by Hairismylife
    That means Histogen-created follicles won't last for long?
    exactly one anagen phase. Once it falls out, you will lose it for good. Since ~100 hairs fall out each day, you will lose those 100 hairs permanently.... scientists are ****ing stupid that's all I have to say

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  • Hairismylife
    replied
    Originally posted by 2020
    right, so I'm guessing 100% of people didn't know that actual follicle size changes from cycle to cycle... that makes Histogen and all other stimulants useless

    http://www.hairdoc.com/book/Chapter_...ss_answers.pdf
    That means Histogen-created follicles won't last for long?

    Leave a comment:


  • 2020
    replied
    Originally posted by gutted
    dude i dont think im going anywhere with you. Link me to the spurce of that info.
    right, so I'm guessing 100% of people didn't know that actual follicle size changes from cycle to cycle... that makes Histogen and all other stimulants useless

    Trusted Board Certified Dermatologists serving Cow Hollow San Francisco, CA. Contact us at 415-907-7354 or visit us at 2001 Union Street, Suite 520, San Francisco, CA 94123: Hair Doc

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  • gutted
    replied
    Originally posted by 2020
    miniaturization, shrinkage whatever. Read this post:
    If it were PGD2 why don't transplanted hairs, or horseshoe hairs, fall out? have they tested bald areas and non-bald areas on the SAME scalp?


    FOLLICLE SIZE naturally changes as it goes from cycle to cycle. DO YOU AGREE?
    dude i dont think im going anywhere with you. Link me to the spurce of that info.

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