If it were PGD2.....

[2020]

NO

10char

for it to be like that, PGD2 has to be THE RESULT of MPB and not really the cause...

someone mentioned that perhaps PGD2 just puts hair into telogen phase and the actual follicle shrinkage is meaningless since follicle size goes up and down depending on the phase?

[gutted]

exactly! But that mechanism is broken in balding people and I don't think Histogen will be able to TRULY reverse it. Yeah it will be able to mimic those growth factors to simulate another hair phase but that growth is "fake" since your follicle is still "broken" and won't be able to repeat that anagen phase again...

NO, once stimulated the body will cycle it normally.

[gutted]

ok let's say you get a 1000 histogen injections and now you're a thick NW1. Then you get castrated. Will Histogen's hair fall off eventually? Yes or No?

NO

10char

[2020]

dude you cant say that, when hairs are proliferating i.e growing, growth factors are continually being secreted every single day, theres no reason to think histogen will wear off unless you have not addressed your underlying problems.

exactly! But that mechanism is broken in balding people and I don't think Histogen will be able to TRULY reverse it. Yeah it will be able to mimic those growth factors to simulate another hair phase but that growth is "fake" since your follicle is still "broken" and won't be able to repeat that anagen phase again...

[2020]

dude, we dont know the details, all you can do is speculate, i personally think once the hair starts growing through histogens injection, the body will takeover and cycle the hairs normally.

If your unlucky and your adrogen levels havent balanced out through age, those hairs will minuturise again. So yes "dht" levels are still a factor with histogen.

ok let's say you get a 1000 histogen injections and now you're a thick NW1. Then you get castrated. Will Histogen's hair fall off eventually? Yes or No?
My guess is that it will since they should only last one phase due to your follicles not being able to control cycling....

[gutted]

one anagen phase so 2-3 years. Depending on how fast you shed, that fallen hair won't grow back...

dude you cant say that, when hairs are proliferating i.e growing, growth factors are continually being secreted every single day, theres no reason to think histogen will wear off unless you have not addressed your underlying problems.

Histogen probably works through stimulating wound regeneration, is it a coicidence that acell is used for wound regeneration too and grows at least some hair in some individuals...

[2020]

and is it really a problem that you would get histogen treatment every 2-3 years?

.... your MPB is still progressing though... more and more follicles will fail to enter anagen phase and you will need more and more injections and then you will become a NW6 and you won't be able to keep up with the injections it's going to be ridiculous.

yes this is a HUGE problem

[gutted]

I'm not confident about that at all.... are you saying that Histogen hairs will last as long as it takes for DHT to shrink it or will it at last as long as when Histogen growth factors wear off?

dude, we dont know the details, all you can do is speculate, i personally think once the hair starts growing through histogens injection, the body will takeover and cycle the hairs normally.

If your unlucky and your adrogen levels havent balanced out through age, those hairs will minuturise again. So yes "dht" levels are still a factor with histogen.

[25 going on 65]

If I had to get re-injected every 24-36 months I would still do it.

Still a hell of a lot more convenient than twice-daily minox. Or getting a chunk of scalp sliced out the back of my head.

[ovoxo]

and is it really a problem that you would get histogen treatment every 2-3 years?

[2020]

so you would need histogen injection like once a year or so?

one anagen phase so 2-3 years. Depending on how fast you shed, that fallen hair won't grow back...

[2020]

im confident histogen will last quite some time and not one cycle. It will stimulate the body to cycle dormant hairs again. Only time will tell though.

I'm not confident about that at all.... are you saying that Histogen hairs will last as long as it takes for DHT to shrink it or will it at last as long as when Histogen growth factors wear off?

[ovoxo]

Histogen CAN provide those growth factors to artificially simulate another anagen phase for you, but after that phase is over your body couldn't reproduce those growth factors again for another phase so you would need Histogen growth factors again....

so you would need histogen injection like once a year or so?

[gutted]

right so something went permanently wrong when your body can't reproduce follicles again at normal size....



now where did you get that number? Are you saying that Histogen's growth will wear off due to DHT/PGD2 or because they only last one phase?

im confident histogen will last quite some time and not one cycle. It will stimulate the body to cycle dormant hairs again. Only time will tell though.

[2020]

When its time to regenerate during early anagen the hair follcile begins to grow back to normal size but in mpb individuals the size of the follicle develops/regenerates partially minuturised and not to full size.

right so something went permanently wrong when your body can't reproduce follicles again at normal size....

histogen will last a decent length of time if inflamation is addressed. If not it will last probably 2/3 hair cycles, until it becomes dormant again.

now where did you get that number? Are you saying that Histogen's growth will wear off due to DHT/PGD2 or because they only last one phase?