PGD2, betamethasone valeratel, and hair growth....
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right I'm just disappointed at all those people who tried solving MPB 10 years ago... so many "unfinished" theories. Why can't we just make a list and then once we prove some theory false we just check it off or somethingComment
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like i said, no one wants to waste time and hair on something thats not scientifically proven.Comment
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heres some more info - http://www.dermattikon.gr/magazines/...S%20EN.pdf
i think its best to stick with the betamethasone valeratel.
we know hypertrichosis can be a side effect with that, with the rest of the stuff we're just guessing it could grow hair.
beta has been included in minox,we know it grows hair and could be the reason minox grows hair
but clobetasol has some AMAZING before/after pictures in that study I posted about AA and clobetasol and pimaminuuss-whatever
it's a toss up between the two. I think beta is the safer steroid of the two but I don't knowComment
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Men with androgenic alopecia typically have higher levels of 5-alpha-reductase, lower levels of total testosterone, higher levels of unbound/free testosterone, and higher levels of total free androgens including DHT.[15][16]
Sex hormone-binding globulin (SHBG), which is responsible for binding testosterone and preventing its bioavailability and conversion to DHT, is typically lower in individuals with high DHT.The aim of this study was to evaluate the effect of supplementing healthy men with soy isoflavones on the serum levels of sex hormones implicated in prostate cancer development. A total of 28 Japanese healthy volunteers (18 equol producers and 10 equol non-producers) between 30 and 59 years of age were given soy isoflavones (60 mg daily) supplements for 3 months, and the changes in their sex hormone levels were investigated at the baseline and after administration. The serum and urine concentrations of daidzein, genistein, and the levels of equol in the fasting blood samples and 24-h stored urine samples were also measured. All 28 volunteers completed the 3-month supplementation with isoflavone. No changes in the serum levels of estradiol and total testosterone were detected after 3-month supplementation. The serum levels of sex hormone-binding globulin significantly increased, and the serum levels of free testosterone and dihydrotestosterone (DHT) decreased significantly after 3-month supplementation. Among the 10 equol non-producers, equol became detectable in the serum of two healthy volunteers after 3-month supplementation. This study revealed that short-term administration of soy isoflavones stimulated the production of serum equol and decreased the serum DHT level in Japanese healthy volunteers. These results suggest the possibility of converting equol non-producers to producers by prolonged and consistent soy isoflavones consumption.Comment
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yes, betamethasone valeratel AND Clobetasol Propionate both have hypertrichosis as side effects
beta has been included in minox,we know it grows hair and could be the reason minox grows hair
but clobetasol has some AMAZING before/after pictures in that study I posted about AA and clobetasol and pimaminuuss-whatever
it's a toss up between the two. I think beta is the safer steroid of the two but I don't knowComment
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"Pimecrolimus is a macrolactam of the immunosuppressant class. It is a selective inhibitor of pro-inflammatory cytokines and mediators in T cells and mast cells." (source: some website)
mast cells produce PGD2
"Conclusion: In conclusion, we detected that topical pimecrolimus treatment is as effective as topical corticosteroids and is superior to topical corticosteroids in terms of side effects in the treatment of AA."
source: http://informahealthcare.com/doi/abs...34.2011.590788
thusly, we should use pimecrollimusComment
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it has to be some of the best regrowth ever recorded... not sure how people missed this... I guess it's because it happened before the immune system and PGD2 was implicated? in other words, it was when they thought AA was vastly different than MPBComment
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A lot of people affected by AA end up cured spontaneouslyComment
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I'm starting treatment now as I have some of the foam. Can anybody get ahold of the journal article? I'd like to know how often and how long the presecribed the use of the foamComment
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