CB-03-01 - new antiandrogenic

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  • Pentarou
    Senior Member
    • Apr 2013
    • 482

    #76
    What I want to know is how/when we can get news from the company that is developing the real CB-03-01 for market. Do they ever announce anything?

    Comment

    • yan
      Senior Member
      • May 2013
      • 156

      #77
      02 Aug 2013, Lainate - Half year results - Maybe also some news about CB-03-01
      Jan 2014, Lainate - R&D Day - Detailed infos about all their products, also CB-03-01

      Product pipeline: http://www.cosmopharmaceuticals.com/.../pipeline.aspx

      They plan to file an IND for alopecia in January 14. Proof of Concept studies (Phase 1 + 2a) should be finished around March 15.

      I just want it now!

      Comment

      • burtandernie
        Senior Member
        • Nov 2012
        • 1563

        #78
        I think its definitely jumping the gun to cite a pretty small preliminary study they did already as proof it has no sides and is 2 times as strong as finasteride. It could turn out to be true hopefully, but there is a reason they are studying this for years to come its not just to waste time and money.
        Very dangerous to use this at the stage this is at. I realize some men are desperate, but if your not I would wait more.

        Comment

        • clandestine
          Senior Member
          • Aug 2011
          • 2002

          #79
          Originally posted by burtandernie
          I think its definitely jumping the gun to cite a pretty small preliminary study they did already as proof it has no sides and is 2 times as strong as finasteride. It could turn out to be true hopefully, but there is a reason they are studying this for years to come its not just to waste time and money.
          Very dangerous to use this at the stage this is at. I realize some men are desperate, but if your not I would wait more.
          Desperation stems from the inability to use current treatments, as they have proven entirely ineffective, and even harmful.

          Comment

          • Hairismylife
            Senior Member
            • Jun 2012
            • 383

            #80
            What's the vehicle of CB?

            Comment

            • KO1
              Senior Member
              • Jan 2012
              • 805

              #81
              Originally posted by burtandernie
              I think its definitely jumping the gun to cite a pretty small preliminary study they did already as proof it has no sides and is 2 times as strong as finasteride. It could turn out to be true hopefully, but there is a reason they are studying this for years to come its not just to waste time and money.
              Very dangerous to use this at the stage this is at. I realize some men are desperate, but if your not I would wait more.
              It's a mistake to say it won't have sides, we need to find out what happens with elevated levels of cortexolone in the body.

              Otherwise you know, Cosmo is just taking advantage of balding mens' insecurities. LMAO.

              Comment

              • tdo
                Member
                • Oct 2012
                • 30

                #82
                Isnt the hairloss and acne the same formula but just different vehicle?

                Arent they already testing this for acne on humans? If they are and there arent any adverse effects for acne, I doubt there would be any for hair loss....

                Comment

                • TO YOUNG TO RETIRE
                  Senior Member
                  • Mar 2013
                  • 638

                  #83
                  we need to get this,

                  Comment

                  • yan
                    Senior Member
                    • May 2013
                    • 156

                    #84
                    Well they already tested CB 03 01 for acne in a phase 2 european pilot study. No sides reported, so I assume there wont be any (at least systemic) side effects with the alopecia formula as well.

                    Phase 2 European Pilot study for acne: http://intrepidthera.com/wp-content/...ifu-et-al-.pdf

                    I`m a bit worried about local side effects, especially if you use it for many years. Per example steroid atrophy and other things...

                    They expect to finish US phase 2 acne tests in Q1 2014, so we will "soon" have more info about possible side effects.

                    Comment

                    • Cory
                      Member
                      • Jun 2011
                      • 32

                      #85
                      How strong is CB gonna be, because Histogen didn't provide any great results, Follica, Aderans and Replice are quiet, Tokyo lab is at least decade away, could this formula grow hair on bald scalp?

                      Comment

                      • yan
                        Senior Member
                        • May 2013
                        • 156

                        #86
                        It`s at best a stronger fin without systemic side effects. Grow hair on bald scalp? Dont think so... CB only blocks DHT + Test, I guess thats not the "real solution", even though it showed like 50% increase in Follicular density (n°/cm2) in early proof of concept studies...



                        But they applied it twice a week via iontophoresis. No one knows at the moment what results we can expect if used with a topical vehicle.

                        Comment

                        • Cory
                          Member
                          • Jun 2011
                          • 32

                          #87
                          Originally posted by yan
                          It`s at best a stronger fin without systemic side effects. Grow hair on bald scalp? Dont think so... CB only blocks DHT + Test, I guess thats not the "real solution", even though it showed like 50% increase in Follicular density (n°/cm2) in early proof of concept studies...



                          But they applied it twice a week via iontophoresis. No one knows at the moment what results we can expect if used with a topical vehicle.
                          That's a problem, I am losing hair and in few yrs I might completely have bald scalp, then what, my best hope are guys from Tokyo, but that's decade away and I'll be 38 yrs old, not old but not really young.

                          I have no hope of promising treatment coming unexpectedly.

                          Comment

                          • yan
                            Senior Member
                            • May 2013
                            • 156

                            #88
                            Well if CB is able to keep the hair on your head you have (with some regrow) without major systemic and local side effects, you could easily go for some hair transplants and use CB for years to come until hopefully a final solution arrives (Per example Tokyo guys).

                            Let me tell you, I`m in a similar situation like you. I tried fin 1 mg for 5 months, got too much sides, stopped it. But now I realized, if I want to profit from future treatments like CB, I have to + / - maintain what I have now.

                            So I started using fin again 2.5 months ago (0.375mg a week!). Apart from a bit lower libido, no side effects (I had strong sides with 1mg after 3-4 weeks). I have no idea if it stops my hair loss completely, but it slows it for sure and it gives me the feeling that I do something against it, so to be honest, I dont care that much about it at the moment. I shave my head to 5mm every two weeks and I look good and feel amazing I just dont want to be completely bald, NW3-NW4 till CB comes out would be ok for me. I dont need to style my hair, I just shave it short. But between short and nothing is a difference...

                            Hair transplants: Even though I take a mini dose fin, I would never ever go for a hair transplant, bcs it would force me to take fin for the rest of my life (if CB and others fail) if I dont want to look like shit with hairs in front and rest gone... That could change with CB per example...

                            I need the option to stop fin if other treatments fail. To take even 0.375mg a week for a decade till Tokyo guys got the solution is crazy. I`m not willing to do that. My hope is CB, if they fail, bye bye hairs and bye bye fin.

                            Comment

                            • KO1
                              Senior Member
                              • Jan 2012
                              • 805

                              #89
                              CB is most similar to RU, but with fewer sides.


                              In theory. Unless you're sensitive to cortisol.

                              Comment

                              • clandestine
                                Senior Member
                                • Aug 2011
                                • 2002

                                #90
                                Originally posted by KO1
                                CB is most similar to RU, but with fewer sides.


                                In theory. Unless you're sensitive to cortisol.
                                Any way to know or test if someone is sensitive to cortisol /corticosteroids?

                                Comment

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