Histogen Update - Spencer Kobren Speaks With Dr. Craig L. Ziering

[NeedHairASAP]

Really don't appreciate your arrogance here. What exactly makes you the expert on how minoxidil works? Especially considering that even the scientists who have specifically researched it don't even know it's precise mechanism.

tracy knows all moron. I cant believe you're questioning her.

[Nilli57211]

You are allowed to believe anything you want to believe. Even when it isn't true.

Really don't appreciate your arrogance here. What exactly makes you the expert on how minoxidil works? Especially considering that even the scientists who have specifically researched it don't even know it's precise mechanism.

[UK_]

I was referring to the damage that all those tiny injection sites in your recipient area could be causing. I dont care about any scar from the donor being filled in.

So is it a consensus that if you have an ht your recipient area will have lots of micro scarring(or whatever) underneath the skin in the recipient(hairline crown etc) and it is likely to reduce any histogen like treatments success rate on an individual?

I had 2 ops in the same area so Im guessing ive done some irreversible damage and histogen wont be able to create new growth in those areas?

ops done in 2008. no noticeable loss since then. not on fin/minox

really hope I have not fukxed myself

I wouldnt worry too much, im sure hair systems will still be available even when Histogen does come out. lol only joking, no seriously, likely the HSC will cause the transplanted hair to grow more follicular units, this is why a HT combined with HSC would be amazing for density.

[sickly_burnt_tree_forest]

everyone always cares about their hair loss no matter what the stage of the disease. Im excited to see how histogen will work combined with hair transplants. Im one that believes there is hope for a bald scalp to gain significant coverage in the next 10 years with the future treatments combined with transplants. I think that is realistic.

[Maradona]

I was referring to the damage that all those tiny injection sites in your recipient area could be causing. I dont care about any scar from the donor being filled in.

So is it a consensus that if you have an ht your recipient area will have lots of micro scarring(or whatever) underneath the skin in the recipient(hairline crown etc) and it is likely to reduce any histogen like treatments success rate on an individual?

I had 2 ops in the same area so Im guessing ive done some irreversible damage and histogen wont be able to create new growth in those areas?

ops done in 2008. no noticeable loss since then. not on fin/minox

really hope I have not fukxed myself

you'll be fine.

Just don't assume histogen will cure us. It's too early to tell, it will most likely hit the market in 2018 by then most of us will be slick bald or not care about hair loss.

[CAlex]

I was referring to the damage that all those tiny injection sites in your recipient area could be causing. I dont care about any scar from the donor being filled in.

So is it a consensus that if you have an ht your recipient area will have lots of micro scarring(or whatever) underneath the skin in the recipient(hairline crown etc) and it is likely to reduce any histogen like treatments success rate on an individual?

I had 2 ops in the same area so Im guessing ive done some irreversible damage and histogen wont be able to create new growth in those areas?

ops done in 2008. no noticeable loss since then. not on fin/minox

really hope I have not fukxed myself

[TheDude]

Wow!

Those are some good results..

Histogen are the real deal..

Definitely on UK's side of the argument..

[Kiwi]

Dr Ziering has already stated it will be very difficult for HSC to work in scar tissue, so regenerating hair in areas you've had a transplant wont be guranteed by HSC.

That's not a problem for people with Strip Scars though. You'll be able to get coverage up top with Histogen and then FUE into scar.

Problem solved.

[Kiwi]

no idea!

I would hold off on a transplant for at least the next year to see how all these treatments pan out....

I don't think it will change a thing. I'd still hold off for a year though. It could be 10K you sink on a future treatment vs a HT.

[UK_]

@ 2020

Ive seen you post a few times of the permanent damaging effects of having a ht and that it may seriously effect any treatment that histogen may offer down the line. (not exactly what you wrote)

Do you have any idea how much this could ruin a persons chances of being a good candidate for histogen in the future to achieve optimal results?

p.s. do you think more refined hts(2008 plus) will have less of a damaging effect on scalp.

I usually dont ask these questions but your the only one ive seen post about it, as even the companies said that having hts would not eliminate people from being good candidates for treatments if i recall correctly

Dr Ziering has already stated it will be very difficult for HSC to work in scar tissue, so regenerating hair in areas you've had a transplant wont be guranteed by HSC.

[2020]

@ 2020

Ive seen you post a few times of the permanent damaging effects of having a ht and that it may seriously effect any treatment that histogen may offer down the line. (not exactly what you wrote)

Do you have any idea how much this could ruin a persons chances of being a good candidate for histogen in the future to achieve optimal results?

p.s. do you think more refined hts(2008 plus) will have less of a damaging effect on scalp.

I usually dont ask these questions but your the only one ive seen post about it, as even the companies said that having hts would not eliminate people from being good candidates for treatments if i recall correctly

no idea!

I would hold off on a transplant for at least the next year to see how all these treatments pan out....

[CAlex]

@ 2020

Ive seen you post a few times of the permanent damaging effects of having a ht and that it may seriously effect any treatment that histogen may offer down the line. (not exactly what you wrote)

Do you have any idea how much this could ruin a persons chances of being a good candidate for histogen in the future to achieve optimal results?

p.s. do you think more refined hts(2008 plus) will have less of a damaging effect on scalp.

I usually dont ask these questions but your the only one ive seen post about it, as even the companies said that having hts would not eliminate people from being good candidates for treatments if i recall correctly

[UK_]

Enrollment of 56 patients with male pattern hair loss in the Phase I/II clinical trial of HSC has been completed, and the trial is ongoing. Dr. Gail Naughton, Histogen CEO and Chairman of the Board, presented the 12 week primary safety and efficacy data at the Society for Investigative Dermatology (SID) Annual Meeting on May 11, 2012. The treatment was well-tolerated and no study-related adverse events have been reported. In this second clinical trial of HSC, which was designed with an additional treatment timepoint, the increase in total hair count was 46.5% above that seen in the pilot HSC trial at 12 weeks. Statistical significance was noted in all efficacy endpoints which include increases in total hair count (p=0.0013), terminal hairs (p=0.0135) and hair thickness (p=0.026). A brief on the data presented by Dr. Naughton during the SID Annual Meeting.

http://www.histogen.com/applications/hsc.htm

Music to my ears.

[mpb47]

I don't know about finasteride, but I honestly do not believe that minoxidil or anything that causes an initial shed is really helping your follicles. I believe that all minoxidil does is get your follicles on the same schedule so the hairs are all breaking the surface of your scalp at the same time, creating the appearance of more hair. But it doesn't turn vellus hairs terminal or do any "unminiaturizing." Apparently Histogen does. With Histogen's results and the fact that they have actually made miniaturized hair terminal again WITHOUT a shed, I'm inclined to believe the idea of the initial shed helping your follicles to be utter and complete BS.

Minox has slowed my progression for 15 years now. I have seen it undo some of my miniaturization though in time it started coming back. But don't underestimate minox as it will buy you time.

[UK_]

Even if that treatment were the real deal, it is not a cure - and can never truly be considered a cure.

That is not true. I have benefited from the current treatments and so have many others. Unfortunately nothing works for everyone and for some people nothing works at all.

For male pattern hair loss it would be - if Gho can obtain 80% donor regeneration, we could go from hair transplants that can yield 2,000 grafts to possibly 10,000 grafts & more, those grafts would also be immune to DHT.

You're forgetting the major downfall with hair transplants IS limited donor... but it's also the fact that even with 2,000 FUE grafts a large percentage of them do not make it through the transplant process.

You've no knowledge of Gho's procedure and thus have no inclination to make comments regarding the feasibility of his work.

You are allowed to believe anything you want to believe. Even when it isn't true.

lol eat your heart out.