Will an official cure ever be found? Honestly

[iaskdumbquestions]

Hey Swooping, how are you doing ? I havent really followed Replicel myself. I know one thing though: the stock market never is wrong. REPCF currently trades at 21 cents and has a market cap of a lousy 13M usd, which is a joke, even for an OTC company. It's pretty much all one needs to know.

So not getting my hopes up on replicel ...

Judging a company's pipeline by its valuation is lunacy, and it works the other way around. A company's valuation should be judged by its pipeline, and, in this case, it could signal REPCF is a buy (Not saying it is - I have never performed a valuation on the company). Our specialized knowledge of hair loss would give us an edge over the pension/hedge/mutual fund guys.

Maybe I'll put some money into the company and use those gains to finance my treatment.

[Arashi]

You clearly haven't followed Replicel lately then. Start reading or listen to some interviews/presentations they gave lately and you'll understand what I mean.

Hey Swooping, how are you doing ? I havent really followed Replicel myself. I know one thing though: the stock market never is wrong. REPCF currently trades at 21 cents and has a market cap of a lousy 13M usd, which is a joke, even for an OTC company. It's pretty much all one needs to know.

So not getting my hopes up on replicel ...

[wriggles]

Probably not. Even castration can't bring a NW6 back to a NW1.

Why not? What's the scientific reason?

[Hubris]

If Replicel can immunize AGA, wouldn't that mean that the follicles would re-awaken and then start growing?

So if you inject a NW6 with a DHT killer, doesn't that basically mean that there's nothing to attack the follicle so it would begin to grow again?

Probably not. Even castration can't bring a NW6 back to a NW1.

[dutchguyhanging]

I have, they stated a patient might need multiple injections to achieve full head of hair. They haven't confirmed or ruled that out, current trials are testing that. I don't see how anybody can just come to the conclusion that it won't be a cure.

I think swooping has to read replicel again.. they havent ruled out anything yet. they want to wait for the results... they are not BSing company thats why they dont want to make any bold statements.... have a look at msg from Replicel on their fb page


RepliCel We believe the newly injected dermal sheath cup cells will migrate into the dormant hair follicles and cause them to grow new hair. We also believe these new hairs will not be affected by the DHT hormone that causes the other hair to fall out because we have isolated cells from the lower back of the scalp where they are not affected. We do not know how far the cells will spread. All of these questions will be answered in our phase 2 clinical trial.

[BoSox]

You clearly haven't followed Replicel lately then. Start reading or listen to some interviews/presentations they gave lately and you'll understand what I mean.

I have, they stated a patient might need multiple injections to achieve full head of hair. They haven't confirmed or ruled that out, current trials are testing that. I don't see how anybody can just come to the conclusion that it won't be a cure.

[wriggles]

I was talking in terms of a full cure reversal. Replicel isn't aimed towards that. They want to provide a preventative functional cure. That's what their hypothesis is based on. There might be some repair happening but it isn't going to be better in that sense than castration.

That's what I call a functional cure. It goes well with the saying "prevention is better than cure". So that might happen in 10 years and is more likely to me.

Replicel isn't going to give you your full head of hair back though. But then again you know miracles do happen, but chances for that are low to non-existent .

Nonetheless if Replicel succeeds in their hypothesis it's f*cking huge anyway as that will spell the end for AGA basically.

After all every man that just starts balding could just get some injections and be immunized to AGA basically. The NW6 won't gain anything from that though.

If Replicel can immunize AGA, wouldn't that mean that the follicles would re-awaken and then start growing?

So if you inject a NW6 with a DHT killer, doesn't that basically mean that there's nothing to attack the follicle so it would begin to grow again?

[lol76]

I was talking in terms of a full cure reversal. Replicel isn't aimed towards that. They want to provide a preventative functional cure. That's what their hypothesis is based on. There might be some repair happening but it isn't going to be better in that sense than castration.

That's what I call a functional cure. It goes well with the saying "prevention is better than cure". So that might happen in 10 years and is more likely to me.

Replicel isn't going to give you your full head of hair back though. But then again you know miracles do happen, but chances for that are low to non-existent .

Nonetheless if Replicel succeeds in their hypothesis it's f*cking huge anyway as that will spell the end for AGA basically.

After all every man that just starts balding could just get some injections and be immunized to AGA basically. The NW6 won't gain anything from that though.

Huh? Is Replicel really that promising?

[Swooping]

How is Replicel not aimed towards that? They are cloning and creating infinite amount of hair.

You clearly haven't followed Replicel lately then. Start reading or listen to some interviews/presentations they gave lately and you'll understand what I mean.

[BoSox]

I was talking in terms of a full cure reversal. Replicel isn't aimed towards that. They want to provide a preventative functional cure. That's what their hypothesis is based on. There might be some repair happening but it isn't going to be better in that sense than castration.

That's what I call a functional cure. It goes well with the saying "prevention is better than cure". So that might happen in 10 years and is more likely to me.

Replicel isn't going to give you your full head of hair back though. But then again you know miracles do happen, but chances for that are low to non-existent .

Nonetheless if Replicel succeeds in their hypothesis it's f*cking huge anyway as that will spell the end for AGA basically.

After all every man that just starts balding could just get some injections and be immunized to AGA basically. The NW6 won't gain anything from that though.

How is Replicel not aimed towards that? They are cloning and creating infinite amount of hair.

[Swooping]

10 years? Replicel will be out a lot sooner than that.

I was talking in terms of a full cure reversal. Replicel isn't aimed towards that. They want to provide a preventative functional cure. That's what their hypothesis is based on. There might be some repair happening but it isn't going to be better in that sense than castration.

That's what I call a functional cure. It goes well with the saying "prevention is better than cure". So that might happen in 10 years and is more likely to me.

Replicel isn't going to give you your full head of hair back though. But then again you know miracles do happen, but chances for that are low to non-existent .

Nonetheless if Replicel succeeds in their hypothesis it's f*cking huge anyway as that will spell the end for AGA basically.

After all every man that just starts balding could just get some injections and be immunized to AGA basically. The NW6 won't gain anything from that though.

[BoSox]

Unfortunately I don't have a ball that tells me what the future will bring mate, haha.

But yeah want my speculative opinion? A full blown reversal cure isn't going to arrive for a minimum of 10 years that is on the market.. Unless a miracle happens.

A somewhat functional cure may arise in the next 10 years, and is more likely in my opinion.

It will most likely come from regenerative therapy or gene therapy imo.

10 years? Replicel will be out a lot sooner than that.

[Swooping]

What do you think the cure will come from, Swooping? And when?

Unfortunately I don't have a ball that tells me what the future will bring mate, haha.

But yeah want my speculative opinion? A full blown reversal cure isn't going to arrive for a minimum of 10 years that is on the market.. Unless a miracle happens.

A somewhat functional cure may arise in the next 10 years, and is more likely in my opinion.

It will most likely come from regenerative therapy or gene therapy imo.

[lol76]

Man, you really count on JAK inhibitors giving us the cure? Prepare, because your dream is extremely likely going to be crushed man.

What do you think the cure will come from, Swooping? And when?

[Swooping]

Pretty much my thoughts exactly. We've moved on from a DHT centered point of view. Got to have DHT to start it all off but castration wont reverse hair loss because the follicle is still suspended in the resting phase. There are those with the "bad" variant of the Androgen receptor gene that still do not bald, or do not bald prematurely. Plus androgen levels decline as we age and the rate of Androgenic Alopecia increases. It makes no sense if you are viewing this completely from an androgen induced point of view. JAK induced Stat 3 protein is responsive to the Androgen Receptor and I believe that interplay is what is causing the cascade of events leading to hair cycle deregulation (and thus miniaturization.) I also believe the JAK studies will prove to be the cure we are looking for, and perhaps sooner rather than later. You would take a cream of highly concentrated JAK inhibitor enough to kick start the growth cycle back, and then use as needed to maintain in the future. Angela Cristiano's paper on topical effects of jak-stat inhibition on the hair follicle was truly enormous and should have all very excited.

Man, you really count on JAK inhibitors giving us the cure? Prepare, because your dream is extremely likely going to be crushed man.