US government owned patent on hair follicle neogensis

[Desmond84]

Dr Beren Atac

Hi guys Lauster's team did launch their website. Here's the link:

http://tissuse.com/

Also, I contacted Dr Beren Atac about her work and attending this years congress and here's her reply:

"........I am very busy with new projects (still on hair and skin) and preparing the data for the next Microfollicle paper..

I submitted an abstract to the hair congress but I don't know yet if I will make it. It will depend also on the travel grant I applied. I guess I'll know more in beginning of August."

Hopefully she gets a travel grant to attend the congress and we get to hear what she's been up to

[JayM]

Lacazette sent one but as far as I'm aware he received no reply.

[luiza]

So??? Has someone sent them an email or called them?! C'mon guys, let's show our interest in their research!

[Renee]

In 2010 dr Lauster said he grew a hair follicle in the lab and predicted by 2015 he was suppose to be able to grow many hairs in the lab and implant it into a scalp. I wonder where they are at now with that research.

[FooFighter]

nah! fully functional organ parts will be a reality in max. 25 years.

iPS cell technology and CRISPR/CAS9 gene editing are the two most important future technologies in biology. once these technologies are evolved and perfected, they can cure EVERY disease. and this will not take 100 years. get yourself a bit informed about those 2 technologies and you will realize their potential.

Yes, just like they cured cancer, heart failure, diabetis, stroke and lot of other diseases. And of course MPB.

They talked for cancer cure almost 30 years and what is the result?

We will not have fully functional organs from stem cells in 25 years from now, because we are still on begining and yet testing on animals most of the therapies.

Dont watch too many youtube videos with “ground breaking“ news of self promoting scientist with their innovative therapies on mouse, lol!

There are diseases who are really hard to be cured, because people must DIE from something. We cant live 200 years.

[joachim]

And? They grown heart which cant be seen with eye. To grown human heart and other organs which will work perfectly on humans it will need probably another 100 years ( if we can grown?). Biology is very different than technology.

We have to learn a lot more for stem cells before we use it in humans. They still give very poor results in therapies.

nah! fully functional organ parts will be a reality in max. 25 years.

iPS cell technology and CRISPR/CAS9 gene editing are the two most important future technologies in biology. once these technologies are evolved and perfected, they can cure EVERY disease. and this will not take 100 years. get yourself a bit informed about those 2 technologies and you will realize their potential.

[FooFighter]

here's another breakthrough achievement which might be interesting:

http://www.sciencedaily.com/releases/2015/07/150717092307.htm

they managed to grow a heart chamber in vitro, on a chip, derived from human skin and then converted to iPS cells, and then differentiated into the heart specific cells.
this is exactly what we need for follicles, but with hair follicle related cells of course.
it's only a matter of effort and time, to find the right mechanism to create the functional follicle 3D structures from iPS. that's the way to go, but unfortunately there are not even a handful of researchers trying this route. all time and effort should be put in this technique rather than tinkering around with new topicals, growth factors and other shit. brand new follicles, grown in the lab, this is what we need, to make baldness a thing of the past.

And? They grown heart which cant be seen with eye. To grown human heart and other organs which will work perfectly on humans it will need probably another 100 years ( if we can grown?). Biology is very different than technology.

We have to learn a lot more for stem cells before we use it in humans. They still give very poor results in therapies.

[joachim]

A very exciting video for everyone on the cutting edge forum Enjoy guys

"Biology is being reduced in cost 5-6 times faster than Moore's Law" Why Bio is the New Digital - Joi Ito keynote

here's another breakthrough achievement which might be interesting:

http://www.sciencedaily.com/releases/2015/07/150717092307.htm

they managed to grow a heart chamber in vitro, on a chip, derived from human skin and then converted to iPS cells, and then differentiated into the heart specific cells.
this is exactly what we need for follicles, but with hair follicle related cells of course.
it's only a matter of effort and time, to find the right mechanism to create the functional follicle 3D structures from iPS. that's the way to go, but unfortunately there are not even a handful of researchers trying this route. all time and effort should be put in this technique rather than tinkering around with new topicals, growth factors and other shit. brand new follicles, grown in the lab, this is what we need, to make baldness a thing of the past.

[joachim]

A very exciting video for everyone on the cutting edge forum Enjoy guys

"Biology is being reduced in cost 5-6 times faster than Moore's Law" Why Bio is the New Digital - Joi Ito keynote

great video, desmond. have seen a lot in there which was news to me. it's amazing how they can create and manipulate organisms at will.
biotechnology is definitely progressing extremely fast these days. i think the next 5 to 10 years will bring more progress than the whole last 100 years. a lot of fundamental stuff is well known today. the right tools (microscopes, screening methods, analysis) are also widely available and more and even better tools are on their way.
i believe, in 10 to 20 years the most important diseases can be cured. there are still very rare diseases which are hard to treat and understand of course. this will probably take another 50 years to solve.

however, unfortunately all that biological progress has no direct relationship to hairloss.
a real cure is still written in stars. i think, in 5 years the latest someone will be able to at least produce a fully functional follicle in the lab, probably from iPS cells. from that day on it will be interesting to see how long it takes for mass production and commercialization.

i believe that lab grown follicles for implantation are the final cure we're all waiting for.
still not sure what to think about replicel. i believe their methods have some merit, and maybe they can rescue dieing hair follicles with their procedure, but the denovo hair regeneration for advanced baldies won't pan out, i think. so it will be a semi cure to stop further loss and maybe regenerate some recently shrunk hairs only.

[JayM]

A very exciting video for everyone on the cutting edge forum Enjoy guys

"Biology is being reduced in cost 5-6 times faster than Moore's Law" Why Bio is the New Digital - Joi Ito keynote

Thanks Desomond. Exciting times indeed.

[Sean]

Lots of biotechnology tried and tested in military. We tend to look at things to help our military personnel. There are tons of contracts available under DARPA for funding of unique research.

Hair , skin grafts, scar removal, removal of shrapnel, etc. we got lots of war wounded that need treatments and is pushing such technology.

Lobbying can prevent certain things reachin the public, esp if there is billions at stake.

[Desmond84]

A very exciting video for everyone on the cutting edge forum Enjoy guys

"Biology is being reduced in cost 5-6 times faster than Moore's Law" Why Bio is the New Digital - Joi Ito keynote

[JayM]

Also with replicel they had to go back to the drawing board because the company supplying their growth medium shelved it. Just like pilifocus and their change to the technology it takes F*cking ages to file this change. At least the delays weren't because of not getting results.

Thanks for the detail on the topical. It does atleast sound like they have a good model to work on instead of rats. I think that could be beneficial to companies such as Unilever, L'Oréal ect as well. They could be sat on a gold mine (due to eu laws on animal testing).

[lacazette]

ELIGIBILITY REQUIREMENTS

Individuals must have a health-professional doctoral degree or its equivalent
and must be able to demonstrate the potential for highly productive patient-
oriented research.In most cases, applicants will have finished
their clinical training and will have had some research experience in either a
laboratory or clinical setting. Candidates should possess aptitudes for
independent, patient-oriented or population-based research (e.g. epidemiology,
behavior, or disease prevention) and should be able to demonstrate a commitment
to the study of diseases that occur in women.
Candidates must be able to demonstrate that after two years of supervised
research and study at the NIH they will have the capacity to reach a level of
competency necessary for independent research support.

During the intramural phase, the Transitional Career Awardee is expected to
spend full time on research and research-related activities. During the
extramural phase, the Transitional Awardee must spend at least 75% of his/her
full-time professional effort conducting research or engaged in research career
development activities.

http://grants.nih.gov/grants/guide/rfa-files/RFA-OD-00-003.html

[lacazette]

This Women's health career development he received is interesting (it maybe won't chnge anything as he's already backing by us army, but still an interesting award :

This award is
designed to support career development experiences leading to independence for
clinical investigators interested in patient-oriented or population-based
research related to women's health. The career development program will provide
an opportunity for investigators to develop solid clinical research skills
during two years of study and research within the environment of the NIH
Intramural Research Programs (IRP). The award will also include a follow-on
two-year period of salary and research support at an academic institution of the
candidate's choice. This period of extramural support will facilitate the
transition to independence as a clinical researcher specializing in research
issues related to women's health.

Salary support for the intramural phase of the program will be provided by
Pfizer Women's Health of Pfizer Inc through a grant to the Foundation for the
National Institutes of Health (FNIH). During this two-year period of career
development, the candidate will engage in supervised clinical research and
career development as a clinical or research fellow in the IRP of one of the NIH
Institutes or Centers. Research support for this segment of the award will be
provided by the assigned NIH Institute or Center. For the second phase of the
award, research and salary support will be provided by ORWH in the form of an
extramural career development award (K22) administered by the assigned NIH
Institute or Center. The career development award will be activated when the
candidate has assumed a suitable, independent research position at an academic
institution.