follicept - what's this?

[NeedHairASAP]

If this were the case, it would be the answer to so many peoples prayers, what are others peoples opinions on needhairs claim?

I want to expand on what I said a little. There is more to follicept's potential success than if they can deliver igf-1 effectively.

1. DHT lowers igf-1 in the dermal papilla, along with other things. So, even if they deliver igf-1 effectively, follicpet may not work because we need other things like vegf, etc.-- but we don't know until follicept's results. I haven't found any studies that test exactly what they're testing.

2. Or, maybe it delivers igf-1 effectively, but DHT degrades it again too fast for it to grow hair. In that case, you may need fin + igf-1.

3. Or, maybe it doesn't deliver igf-1 as effectively as thought (with humans)

4. Or maybe some combination of the above.


Of course they could hit other hitches too. I'm not a scientist or researcher, so take what I'm saying with a large grain of salt. This is just my opinion from what I've seen. My main point is that this is at least worth keeping an eye on (and being polite to the company). If in 3 months they haven't released any findings than you can worry.

[Illusion]

additionally, fin and all the other stuff you mentioned works by blocking DHT. DHT brings down igf-1 in follicles. So again, if they can deliver igf-1 to the follicle, there is probably no reason to block dht or use minox to stimulate igf-1--- because again you are getting igf-1 to the follicles

This would be true if deprivation of igf-1 was the only problem in aga, but this isn't the case right?

[Jagger]

Devon, thank you again for your transparency and interaction with the community. It is really really strange, but very cool. Keep it up

I think I recall you saying you don't expect there to be incremental effects - either it works, or it doesn't. So, it wouldn't make sense for me to slather my head in Follicept as much as possible?

Also, do you foresee Follicept as a treatment for fine hair? I've had fine blonde hair since I was born, which definitely doesn't help since it's thinning now. At one point in high school I was able to use hair products, but for the last 5 years or so, hair products just make my hair look thinner and worse. The plan is for the product to thicken existing hair, right? I'd love to be able to style my mane again

[lupero83]

igf1 study on finasteride

http://www.ncbi.nlm.nih.gov/pubmed/12894070

[kantian]

igf1 study on finasteride

http://www.ncbi.nlm.nih.gov/pubmed/12894070

That's awesome! This makes me think more highly of Follicept. Of course, as others have mentioned, other products exist that include IGF-1, and they don't work. So I really hope Follicept has some novel vehicle.

Question for Devon: Why don't you guys get the same type of lab mice that you tested Follicept on initially and try to use one of the other hair loss products that have IGF-1 on them. If the mice grow hair again, then we have some reason to believe that mice work in some significantly different way from humans when it comes to the interaction of IGF-1 and hair. This procedure might be faster to complete because you might have some of those mice lying around, and it doesn't take much time or money to get other products with IGF-1.

[DanWS]

igf1 study on finasteride

http://www.ncbi.nlm.nih.gov/pubmed/12894070

Nice find. Especially for fin users. Would be interested to hear Devon/Follicept's thoughts on this.

[Kiwi]

Nice find. Especially for fin users. Would be interested to hear Devon/Follicept's thoughts on this.

Does this mean less sides or just better results?

[sdsurfin]

that study has been brought up quite a few times on this thread. There are many studies linking IGF-1 (at the follicle level) to hair growth and cycling. I have learned a lot from talking to those guys, and let me tell you, it's more complicated than you think. There is definitely potential, and I can also vouch for the fact that the doctor running this is an incredibly intelligent, helpful, and capable guy. I can't say yet whether it will work the way they want it to, but I can almost say for certain that it will have an impact. wish them the best. Unlike cotsarellis, they have been incredibly open and helpful.

[Jagger]

I'm still hopeful that the reason they're so confident is because some sneaky person tried it already and knows it worked. If you were in the lab when a potential cure was synthesized, would you not be tempted to try it on yourself? And if it only takes 12 days to see results...

I won't hold my breath, scientific integrity and all, but I still have high hopes for this project. I wonder what the status is on the IGF-1 shipment. And I'm jealous as hell that Devon gets to try it on himself...here's hoping he comes back sporting a crazy thick pompadour.

[stayhopeful]

honestly.. i would do anything to have this in my hands right now... I mean I am extremely grateful they plan to have it out on market as early as summer... can't ask for much more than that...

but if it does what they claim it will do. I say we have a BTT party to celebrate

[BiqqieSmalls]

I mean I am extremely grateful they plan to have it out on market as early as summer

Follicept said by the Fall of 2015. It's almost April and they don't have the IGF-1 shipment yet. However, I am en extreme believer in this product and their release date.

[Dimoxynil]

honestly.. i would do anything to have this in my hands right now... I mean I am extremely grateful they plan to have it out on market as early as summer... can't ask for much more than that...

but if it does what they claim it will do. I say we have a BTT party to celebrate

seriously man chill out. You haven't seen any human results yet

[stayhopeful]

My B, my B, sometimes when you are suffering optimism is the only thing that helps, even if slightly irrational

[follicept]

Wow, that's ludicrous and pretty disconcerting. Why does it cost so much money? Is that how much it costs to bring a new drug to market as well?

The 505(b)2 pathway, which we are pursuing for insulin, since it's already approved (would be the case if we put min/fin in our formulation), costs 50-100M and 3-5 years. A completely new drug is 12-15 years and about 2 billion, by latest figures.

[Jagger]

seriously man chill out. You haven't seen any human results yet

He's not wrong. If it does what they say it will, I'm sure this place will explode. Hell, the whole Internet might.

Minus a couple of characters who post here, anyway.