All Hope is Not Lost, After All

[chasguy]

Androgenetic alopecia is probably best described as a genetic defect, not a disease. All of us here have an idiot gene that tells our hair to stop growing despite the fact that we need it, for example as protection from the sun.

For the same reason, like any genetic defect, it is very hard to treat. You can fight the symptoms, but not the cause. That is why a cure has been difficult to find and why Histogen could be the one.

Its not a defect... in our monkey brothers it is a mark of social status. Likely it is the same in humans, however now our cultures push us to maintain youthful appearance at all costs. This is why women die their hair, shave everything else, struggle to remain then and fight off wrinkles.

[Fixed by 35]

I disagree, there is no evidence for such a theory. Hair loss throughout history has been ridiculed, there is no evidence whatsoever of a bald hierarchy.

[chasguy]

I disagree, there is no evidence for such a theory. Hair loss throughout history has been ridiculed, there is no evidence whatsoever of a bald hierarchy.

In great apes there is, and I was referring to stone tools and cave days... Written history is all recent. Evolutionary development of MPH is a well discussed theory

[Fixed by 35]

I just don't think it's a good theory, even for cavemen. It makes no sense and every shred of evidence we have is that baldness has been seen throughout human history as a bad thing. The suggestion that it marked out social status has no grounding, it's a loose theory at best.

It could just as easily have been a beacon to show a bald man had passed the point of sexual maturity and was therefore no longer eligible. It could have been a sign of age in order for the tribe to disown them because they were now too old to do their fair share of hunting and would be a burden.

Balding could also be a far more recent genetic defect for all we know, that developed far more recently. Like things like skin tags and bags under the eyes, it could just be a mistake of nature that evolution can't irradicate.

All these theories are just as plausible.

[mascott23]

I would prolly have to say that it's a genetic defect. people with androgenetic alopecia (AGA) have shown to have increased risk of cardiovascular disease due to increased levels of aldosterone and an increased risk of insulin resistance. I'm not saying that AGA causes the increased risk of cardiovascular disease or vice versa. but there have been many studies correlating the two. based on this information I think that due to the greater susceptibility of developing cardiovascular problems AGA is a genetic defect that evolution wasn't able to filter out due to great strides in medical advances that allowed individuals with AGA to reproduce.

[chasguy]

I would prolly have to say that it's a genetic defect. people with androgenetic alopecia (AGA) have shown to have increased risk of cardiovascular disease due to increased levels of aldosterone and an increased risk of insulin resistance. I'm not saying that AGA causes the increased risk of cardiovascular disease or vice versa. but there have been many studies correlating the two. based on this information I think that due to the greater susceptibility of developing cardiovascular problems AGA is a genetic defect that evolution wasn't able to filter out due to great strides in medical advances that allowed individuals with AGA to reproduce.

By the time you develop cardiovascular disease you've already reproduced. Effective genes get you to puberty and get you reproduced.. .they don't "care" what happens to you afterward except for where a long life my help ensure your offspring survive. There is good evidence that balding is a social cue that a particular male is engaging in less risky behavior and more socially mature as well as communicating a senior rank in the social order. This includes apes as well as humans. Remember though, we are simply a vehicle for our genes to reproduce. If your genes get passed on, then they are effective. If AGA was shown to 100% cause terminal brain cancer at 50 years old, that would have had zero effect on evolution. Pre-modern times you'd still have been reproducing at 15 years old and the kids would have been out of the "house" by 30

[Dutch_Dude]

anyways, let's hope that histogen will be available in asia by 2013-2014...if it's the real deal, i don't mind flying over there...nice trip!

[Fixed by 35]

There is not a single shred of evidence showing baldness = seniority. There is plenty to show baldness = ridicule.

[CVAZBAR]

Oh, me personally? Dude I don't care if it's 50,000. If it works and it stays on the top of my head for years I'm doing it. I don't need a new car or boat or any of that shit people buy. I
ll be getting out of school in a couple of years and when I make money... hair and a house is really all I give a shit about. Actually... just an apartment.

Everything else comes next.

HAHAHAHA! Thanks dawg. I dont mean it in a bad way but what you wrote made me crack up. " Hair and as house is really all i give a shit about" haha. I truly feel the same way and i understand how it is dealing with this bullshit. That was hilarious. It's funny how growing up i never noticed any bald guys and still dont think bad about any but when It's happening to you, its like the end of the world. Hopefully this shit is not fake and we can end this anxiety.

[Fixed by 35]

If I ever grow my hair back, I will be on one enormous high. That's well worth £50,000 in itself.

But besides that, I still firmly believe it will help my business and give me new confidence, which will see a return on the initial £50,000 outlay.

[PatientlyWaiting]

If I ever grow my hair back, I will be on one enormous high. That's well worth £50,000 in itself.

But besides that, I still firmly believe it will help my business and give me new confidence, which will see a return on the initial £50,000 outlay.

Haha hey speak for yourself, 50k is a lot of money man. I can't afford that but if I had it, i'd definitely trade it in for a full head of permanent hair.

This HSC stuff seems very promising though. I wonder how far along are they right now.

[matlondon]

anyways, let's hope that histogen will be available in asia by 2013-2014...if it's the real deal, i don't mind flying over there...nice trip!

I'LL JOIN YOU. iam already looking at prices of air trip hotel to factor in the cost. so far i have the price of the ticket and hotel and a bit for the treatment need to save at a higher rate.

[jtn]

these results are incredible. Please keep in mind, this was a low dose study done to expose side effects. This wasn't even a trial to determine effectiveness. Propecia doesn't have stats like this, even after more than 10 years on the market as a solution for people.

1 injection, and a small amount. Think of how much room there is for improvement.

[Sogeking]

HAHAHAHA! Thanks dawg. I dont mean it in a bad way but what you wrote made me crack up. " Hair and as house is really all i give a shit about" haha. I truly feel the same way and i understand how it is dealing with this bullshit. That was hilarious. It's funny how growing up i never noticed any bald guys and still dont think bad about any but when It's happening to you, its like the end of the world. Hopefully this shit is not fake and we can end this anxiety.

I feel the same way.
I just wish they either find a long-term effective treatment with irrelevant side-effects (or none at all), or a cure for baldness. I mean even if it is an expensive cure just the fact that there is one, which works, has very good results and so on, is something that helps you to keep going, save money and well live.

For a full head of hair, I would definetly work a lot and save a lot. And to get it back would be a moment in my life topped only with the birth of my child or my wedding.

[gmonasco]

1 injection, and a small amount. Think of how much room there is for improvement.

Indeed, there's room for improvement, but we need to keep in mind that it hasn't yet been demonstrated that the results are compoundable.