About to start RU, need directions...

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  • Pate
    Senior Member
    • Sep 2011
    • 417

    #76
    Originally posted by CVAZBAR
    RU fights DHT, so it's basically a stronger topical version of Fin right? Why would it matter where you apply it? It's still going to decrease the DHT levels won't it? I'm just wondering since people say to apply it on the hair line. What's the difference?
    No, it's nothing like fin.

    Fin is a 5AR inhibitor which blocks the conversion of T to DHT. It's taken internally, spreads throughout your body, and a little bit of it gets into your hair follicles and kills the 5AR in the follicles. This stops T getting converted to DHT in your follicles and then binding to the androgen receptors in the follicle.

    But most of the fin in your body doesn't go into your follicles, it stops DHT production in the rest of your body. Which creates the infamous fin side effects.

    RU is an androgen antagonist. It doesn't decrease DHT levels at all. It just attaches to the androgen receptor and blocks it so that neither DHT nor T can bind to it. You don't want to get RU inside your body or it will block both T and DHT from doing their jobs within your body, including your dick.

    So you apply RU topically to the skin. Some of the RU will get through into the blood and then into your body, but it will get metabolised to one of two main metabolites. One of these is anti-androgenic but less than 1% of the RU molecules go to that. The other 99% goes to another metabolite that is inert.

    They have tested RU up to massive doses in rats (far higher than the equivalent doses in humans used for treating MPB) and they found that there was no measurable change in serum levels of either DHT or T.

    So RU is, apparently, both more effective than fin and with almost no systemic effects. It's still a risk to take it, because there is only a limited amount of scientific literature on RU so we can't be totally sure... but those of us taking it feel the benefits outweight the risks.

    But that's why it has to be applied to the scalp.

    Comment

    • neversaynever
      Senior Member
      • Dec 2011
      • 640

      #77
      RU in kb solution dries very quickly. Often in around 30 mins. Make it an hour to be safe. Once its dry youre fine, as long as she doesnt lick your scalp!

      If you have a woman, dont sleep with RU on your scalp (to be extra safe). Have a look at your routine and see when you can apply and have time to wash it out later. I leave RU+KB on my scalp for 2-3-4 hours and wash out.

      Because its not a huge amount of time I use a dermaroller to increase absorbtion. My routine varies...

      The other day I had RU+KB on my scalp for 90 mins (using a dermaroller before and after application). Then i washed out.

      Its working for me. It dries very quickly, i dont see why you have to keep it on your scalp for 8 hours or more like some people do.

      Comment

      • neversaynever
        Senior Member
        • Dec 2011
        • 640

        #78
        Originally posted by BaldJerry
        Do you really want to risk it? If a woman even handles dut/fin pills it will absorb into their system.You won't be able to find a conrete answer regarding this because you won't be ably to find any human studies on RU. Just the monkey study. This is one of the reasons RU never made it to open market.
        I think alot of these chemicals (RU, CB, PSI and many more) have issues with marketing because theyre so sensitive.

        You can leave your minox at room temperature, mass produce it, ship it all over the world, produce it cheaply. Not with RU...

        It requires care, gets ruined at room temperature, doesnt have a long shelf life unless its in the damn fridge or freezer. I believe that is why these topicals fail for companies. CB is being injected in their trials, and needs special preparation and storage. Its not stuff you can leave in the bath room cupboard for a month, and these chemicals are far more difficult to synthesize than minox.

        I belive thats why alot of them dont make it to market. And sure, without care RU and CB is bad for women, and dangerous for pregnant women, but i dont think thats the main reason it didnt get to market.

        Like i said, RU + KB solution dries VERY quickly. Handle with care guys.

        Comment

        • LongWayHome
          Senior Member
          • Nov 2012
          • 183

          #79
          Originally posted by neversaynever
          Its working for me. It dries very quickly, i dont see why you have to keep it on your scalp for 8 hours or more like some people do.
          Can you please tell me what do you mean by "It's working for me" ?
          Have it maintained? regrowth? both? and what's the dose?
          aand RU using something else like fin/dut..?
          This is very exciting.

          Comment

          • garethbale
            Senior Member
            • Apr 2012
            • 603

            #80
            neversaynever

            do you make up the solution yourself or did you buy it ready made?

            I really can't be bothered to buy ingredients and make it up, plus storage is a problem

            Comment

            • BaldJerry
              Senior Member
              • May 2012
              • 102

              #81
              Originally posted by neversaynever
              I think alot of these chemicals (RU, CB, PSI and many more) have issues with marketing because theyre so sensitive.

              You can leave your minox at room temperature, mass produce it, ship it all over the world, produce it cheaply. Not with RU...

              It requires care, gets ruined at room temperature, doesnt have a long shelf life unless its in the damn fridge or freezer. I believe that is why these topicals fail for companies. CB is being injected in their trials, and needs special preparation and storage. Its not stuff you can leave in the bath room cupboard for a month, and these chemicals are far more difficult to synthesize than minox.

              I belive thats why alot of them dont make it to market. And sure, without care RU and CB is bad for women, and dangerous for pregnant women, but i dont think thats the main reason it didnt get to market.

              Like i said, RU + KB solution dries VERY quickly. Handle with care guys.
              I don't think it's the main reason but probably a reason. Point is I think I would keep away from women to be on safe side cause consequences could be very bad. Who knows why RU really never made it to open market. Probably had safety issues in phase 2 testing.

              Comment

              • Kiwi
                Senior Member
                • Mar 2011
                • 1087

                #82
                Originally posted by BaldJerry
                I don't think it's the main reason but probably a reason. Point is I think I would keep away from women to be on safe side cause consequences could be very bad. Who knows why RU really never made it to open market. Probably had safety issues in phase 2 testing.
                You keep talking about these issues.

                Do you have any links to their phase 2 trial data. Or anything? I havent even read anything about their phase 1 trials... where are you getting this info from?

                Comment

                • torontostringer
                  Junior Member
                  • Oct 2012
                  • 23

                  #83
                  The RU Solution is back for sale on MPB Tr. I'm going to get the 2% to start out. I know it wont be as effective as creating your own batches but it will be easier to ease into using it as a treatment.

                  Comment

                  • hellouser
                    Senior Member
                    • May 2012
                    • 4419

                    #84
                    Originally posted by torontostringer
                    The RU Solution is back for sale on MPB Tr. I'm going to get the 2% to start out. I know it wont be as effective as creating your own batches but it will be easier to ease into using it as a treatment.
                    2% of 1ml usage like Minox is a rather LOW dosage. IrishPride, the dude with phenomenal growth used closer to 100mg per dosage, effectively 10% at 1ml. I would highly advise NOT to bother with 20mg or 2% dosage. It won't be anywhere near as effective. Basically, 20mg vs 100mg is 5X the difference... percentage wise, thats a huge margin.

                    Comment

                    • unwheel
                      Junior Member
                      • Feb 2013
                      • 5

                      #85
                      Hi, I'm new to this forum. Appreciate all the great advice on here.

                      I've just started RU and I'm wondering how everyone avoids getting the solution in their hair. I've read a lot of the RU threads here and it seems a good way is to use a syringe to reach the scalp, which is what I'm doing but after trying to rub it in I still end up with it in my hair and it feels like I'm wasting it.

                      Also need some advice on how to store RU. As I'm new to this I bought MPBTreatments RU and the instructions on the packaging says store at room temperature. Don't most people advise storing it in the fridge?

                      Finally can someone let me know what I should do to get involved with a group buy?

                      Comment

                      • garethbale
                        Senior Member
                        • Apr 2012
                        • 603

                        #86
                        Originally posted by unwheel
                        Hi, I'm new to this forum. Appreciate all the great advice on here.

                        I've just started RU and I'm wondering how everyone avoids getting the solution in their hair. I've read a lot of the RU threads here and it seems a good way is to use a syringe to reach the scalp, which is what I'm doing but after trying to rub it in I still end up with it in my hair and it feels like I'm wasting it.

                        Also need some advice on how to store RU. As I'm new to this I bought MPBTreatments RU and the instructions on the packaging says store at room temperature. Don't most people advise storing it in the fridge?

                        Finally can someone let me know what I should do to get involved with a group buy?

                        Hello mate

                        I don't use RU (yet) so can't comment on how to apply etc, but I think if you get in touch with a guy called Dan26 you might be able to get in on a group buy.

                        Re the storage of RU, I'm pretty sure its the ingredients you store in freezer/fridge if you're making it up. If you're buying it outright and they say store at room temperature, I'm sure this is ok.

                        Comment

                        • hellouser
                          Senior Member
                          • May 2012
                          • 4419

                          #87
                          Originally posted by unwheel
                          Hi, I'm new to this forum. Appreciate all the great advice on here.

                          I've just started RU and I'm wondering how everyone avoids getting the solution in their hair. I've read a lot of the RU threads here and it seems a good way is to use a syringe to reach the scalp, which is what I'm doing but after trying to rub it in I still end up with it in my hair and it feels like I'm wasting it.
                          Not much You can do, really. Unless you wanna go all out like Irishpride and shave your head and be guaranteed maximum coverage. I'm willing to bet thats part of the reason why his results were so ridiculously good.


                          Also need some advice on how to store RU. As I'm new to this I bought MPBTreatments RU and the instructions on the packaging says store at room temperature. Don't most people advise storing it in the fridge?
                          You should at least keep it in the fridge but best if in freezer. Room Temperature will cause your solution to lose its efficacy overtime. Keep it sealed airtight and away from light.

                          Finally can someone let me know what I should do to get involved with a group buy?
                          You should leave a comment of LilPauly's profile page and get in touch with him, he's usually one of the guys that runs the group buys.

                          As far as I know, he's going to be doing a CB group buy soon. I'm thinking of joining that and using RU mixed with Minoxidil 6 hours before applying CB... should be a pretty good combo.

                          Comment

                          • LongWayHome
                            Senior Member
                            • Nov 2012
                            • 183

                            #88
                            hellouser are you mixing RU with minox? so without the PG and alcohool or what?

                            Btw combo of RU and CB sounds too powerful man, you'll get immortality...

                            Comment

                            • hellouser
                              Senior Member
                              • May 2012
                              • 4419

                              #89
                              Originally posted by LongWayHome
                              hellouser are you mixing RU with minox? so without the PG and alcohool or what?

                              Btw combo of RU and CB sounds too powerful man, you'll get immortality...
                              I use RU at night before bed at 5-10% (1ml = 0.7ml of alcohol and 0.3ml of PG + 50-100mg of RU). I use Minoxidil (Made by kirkland) 6 hours prior to RU application.

                              But if I get my hands on CB, I'll buy another batch of RU, 10grams and mix it in my Kirkland's Minoxidil. RU + CB + Minox vs. Finasteride shouldn't stand a chance..... at least on paper. We'll see how things go. My temples and overall hairline still needs to be lowered... f*ck.

                              Comment

                              • LMS
                                Senior Member
                                • Dec 2012
                                • 226

                                #90
                                So are any of you guys seeing any regrowth or mostly just maintainence?

                                Comment

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