No, it's nothing like fin.
Fin is a 5AR inhibitor which blocks the conversion of T to DHT. It's taken internally, spreads throughout your body, and a little bit of it gets into your hair follicles and kills the 5AR in the follicles. This stops T getting converted to DHT in your follicles and then binding to the androgen receptors in the follicle.
But most of the fin in your body doesn't go into your follicles, it stops DHT production in the rest of your body. Which creates the infamous fin side effects.
RU is an androgen antagonist. It doesn't decrease DHT levels at all. It just attaches to the androgen receptor and blocks it so that neither DHT nor T can bind to it. You don't want to get RU inside your body or it will block both T and DHT from doing their jobs within your body, including your dick.
So you apply RU topically to the skin. Some of the RU will get through into the blood and then into your body, but it will get metabolised to one of two main metabolites. One of these is anti-androgenic but less than 1% of the RU molecules go to that. The other 99% goes to another metabolite that is inert.
They have tested RU up to massive doses in rats (far higher than the equivalent doses in humans used for treating MPB) and they found that there was no measurable change in serum levels of either DHT or T.
So RU is, apparently, both more effective than fin and with almost no systemic effects. It's still a risk to take it, because there is only a limited amount of scientific literature on RU so we can't be totally sure... but those of us taking it feel the benefits outweight the risks.
But that's why it has to be applied to the scalp.
Fin is a 5AR inhibitor which blocks the conversion of T to DHT. It's taken internally, spreads throughout your body, and a little bit of it gets into your hair follicles and kills the 5AR in the follicles. This stops T getting converted to DHT in your follicles and then binding to the androgen receptors in the follicle.
But most of the fin in your body doesn't go into your follicles, it stops DHT production in the rest of your body. Which creates the infamous fin side effects.
RU is an androgen antagonist. It doesn't decrease DHT levels at all. It just attaches to the androgen receptor and blocks it so that neither DHT nor T can bind to it. You don't want to get RU inside your body or it will block both T and DHT from doing their jobs within your body, including your dick.
So you apply RU topically to the skin. Some of the RU will get through into the blood and then into your body, but it will get metabolised to one of two main metabolites. One of these is anti-androgenic but less than 1% of the RU molecules go to that. The other 99% goes to another metabolite that is inert.
They have tested RU up to massive doses in rats (far higher than the equivalent doses in humans used for treating MPB) and they found that there was no measurable change in serum levels of either DHT or T.
So RU is, apparently, both more effective than fin and with almost no systemic effects. It's still a risk to take it, because there is only a limited amount of scientific literature on RU so we can't be totally sure... but those of us taking it feel the benefits outweight the risks.
But that's why it has to be applied to the scalp.
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