Any topical treatment to look forward to in the future?

[maxhair]

a lot of these trials are to measure other health benefits... so they test women with menopausal symptoms or something like that. Normal women won't grow more hair with DHT blockers...



some of them probably

Here's an email response I got from Folexen, who sell equol:

Dear Maxhair,

Thanks for your query.

We have not done official clinical trials because it is being provided as a
cosmetic treatment rather than a medication.

However we recently undertook an evaluation of the treatment's
effectiveness, which you can find some details of here:

http://folexen.com/public/S-equol_eval_10mg_oral_BD_summary.zip

Note that the examined area was small (1cm x 1cm) and only 45 people were in
the sample. So even though the results are statistically significant, they
should be viewed conservatively. Subjects on equol saw an overall 2.5%
density increase over 6 months within a reasonable confidence band.

We plan on doing some larger studies in the future.

Feel free to let me know if you have any other questions.

Regards,

[2020]

lol I sent them an email asking how is it possible that equol is more expensive that meth:

Hi 2020,

There are some exhaustive purification steps, but also the machinery and lab
gear are expensive so unfortunately that makes the product a little
expensive too.

It's still cheaper than meth though, I guess :P

Regards,
Andrew

[2020]

2.5%? bullshit. Yeah it won't regrow much hair because it only prevents further DHT interactions but even fin displayed 10-20% growth...

Explain this:




^ check the difference between those two dark blue bars. Equol obviously made a huge difference

edit:

Experimentals took two size "0" capsules containing 2.5mg S-equol & potato starch, twice a day for 168 days.

2.5mg is way too little! They need to use at least 100mg so that's why I complained that it's so expensive due to us needing to use at least 100mg daily.

[Maradona]

2.5%? bullshit. Yeah it won't regrow much hair because it only prevents further DHT interactions but even fin displayed 10-20% growth...

Explain this:




^ check the difference between those two dark blue bars. Equol obviously made a huge difference

edit:


2.5mg is way too little! They need to use at least 100mg so that's why I complained that it's so expensive due to us needing to use at least 100mg daily.

Hey 2020 can you explain how equol works? I'm interested.

How does it lower DHT? I think the way a treatment lowers DHT is very important for side effects regardless of what clinical trials say.

[2020]

Hey 2020 can you explain how equol works? I'm interested.

http://folexen.com/HowItWorks.aspx

^ pretty much what they're saying.

The people from that site also did their own study and found that it only takes 5mg a day to halt MPB and give 2% regrowth for most people even though the dose is AT LEAST TEN TIMES SMALLER than it should be.... obviously it does something. Higher doses of that stuff are definitely capable of stopping MPB. The higher the dose, the greater the effects unlike with fin or dut.

How does it lower DHT? I think the way a treatment lowers DHT is very important for side effects regardless of what clinical trials say.

why regardless? Massive doses have been tested on real people with no side effects. Keep in mind that billions of people are able to produce this molecule naturally when eating soy products and they're not having side effects....

If you can't produce this molecule naturally, then you must take it in its "raw" form.

[Maradona]

http://folexen.com/HowItWorks.aspx

^ pretty much what they're saying.

The people from that site also did their own study and found that it only takes 5mg a day to halt MPB and give 2% regrowth for most people even though the dose is AT LEAST TEN TIMES SMALLER than it should be.... obviously it does something. Higher doses of that stuff are definitely capable of stopping MPB. The higher the dose, the greater the effects unlike with fin or dut.



why regardless? Massive doses have been tested on real people with no side effects. Keep in mind that billions of people are able to produce this molecule naturally when eating soy products and they're not having side effects....

If you can't produce this molecule naturally, then you must take it in its "raw" form.

Ah nice, thanks for the links. You probably are the only dude on baldtruth who knows his shit but i gotta disagree with you on this stuff. I don't really like the idea of depriving the body of DHT altogether, is this what this treatment does?

It says it binds to DHT so that sounds to me same as fin. If it can't bind to AR receptors then DHT will not be doing what it is supposed to do in other parts in your body.

[2020]

I don't really like the idea of depriving the body of DHT altogether, is this what this treatment does?

okay but you do realize that your body contains its own androgen binding proteins such as SHBG which inhibit the function of sex hormones like DHT?
http://en.wikipedia.org/wiki/Sex_hor...f_sex_hormones (read: The SHBG inhibits the function of these hormones.)

Raising your own SHBG levels would help a lot but it is very hard so you might as well use equol which does something similar.

"Disabling" existing DHT which was already converted from T would have no side effects.

Equol is nothing like finasteride.

[Kirby_]

kirby: there is far to much money to be made in the hairloss industry. There are quite afew companies working on products as we speak, all wanting to get out first to get there market space set, no doubt a new company will want to better said company and release a newer better product.

I'm just extremely doubtful now than anything will become mainstream, readily-available products. Some new substances will be available (expensively) on the black market, somehow, but the longer I read hairloss forums, the most I discover how many potential new treatments over the years that were under development lead to nothing. It's terribly depressing. Equol is just another.

[2020]

I'm just extremely doubtful now than anything will become mainstream, readily-available products. Some new substances will be available (expensively) on the black market, somehow, but the longer I read hairloss forums, the most I discover how many potential new treatments over the years that were under development lead to nothing. It's terribly depressing. Equol is just another.

well the goal right now is to maintain as much hair as you can before Histogen and those other treatments arrive...

I'm suggesting equol because it won't wear off after 5 years and it has no side effects so anyone can take it.
Equol is PROVEN TO WORK it's just that big pharma is not interested in making it so you're stuck with a few small companies who are charging a lot for it...

[yeahyeahyeah]

well the goal right now is to maintain as much hair as you can before Histogen and those other treatments arrive...

I'm suggesting equol because it won't wear off after 5 years and it has no side effects so anyone can take it.
Equol is PROVEN TO WORK it's just that big pharma is not interested in making it so you're stuck with a few small companies who are charging a lot for it...

So why aren't you using it, and are there any success stories with this product?

This shit reminds me of when some guy released "density" which was equol based.

[yeahyeahyeah]

So why aren't you using it, and are there any success stories with this product?

This shit reminds me of when some guy released "density" which was equol based.

The other problems is, like fin this is essentially binding onto free DHT - how do we know that will not be used in other parts of the body?

Thus, you are depriving your body of DHT.

[yeahyeahyeah]

okay but you do realize that your body contains its own androgen binding proteins such as SHBG which inhibit the function of sex hormones like DHT?
http://en.wikipedia.org/wiki/Sex_hor...f_sex_hormones (read: The SHBG inhibits the function of these hormones.)

Raising your own SHBG levels would help a lot but it is very hard so you might as well use equol which does something similar.

"Disabling" existing DHT which was already converted from T would have no side effects.

Equol is nothing like finasteride.

I don't get it.

But it says it binds onto free DHT disabling it after it has been created.

As maradona said, this is exactly what fin does only it just prevents the DHT from being created in the first place.

[2020]

So why aren't you using it, and are there any success stories with this product?

It's hard to find legitimate sources for it. I found a good one:

http://folexen.com/

but it's way too expensive...

This shit reminds me of when some guy released "density" which was equol based.

I'm aware of them but their website looks very shady.... I wouldn't be sure if I was buying a legit product or not.

[yeahyeahyeah]

It's hard to find legitimate sources for it. I found a good one:

http://folexen.com/

but it's way too expensive...

I have cash to burn, I would try this product out.

But I am not convinced by the science behind it, see above.

[2020]

I don't get it.

But it says it binds onto free DHT disabling it after it has been created.

As maradona said, this is exactly what fin does only it just prevents the DHT from being created in the first place.

it's poorly worded. It says that even though you produce a lot of sex hormones, only a small fraction is biologically active because they're mostly bound up with SHBG and Albumin....
Whatever little is left over is what's causing your MPB but equol will take care of it by binding to it and deactivating it.