If it were PGD2.....

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  • gutted
    Senior Member
    • Jan 2011
    • 1397

    #61
    Originally posted by 2020
    what for? I responded with: your body is able to enlarge and shrink follicles based on whatever cycle it's currently on. non-balding people can't do that - the follicle is stuck in resting phase.
    HISTOGEN can provide some growing that will enlarge follicles again for ONE ANAGANE PHASE AGAIN but once it goes into telogen phase, you won't have the capability to turn them into anagen hair again....

    why can't you understand what I'm saying?
    cause you are talking out out of your ass!!! loooool

    minutrisation is a term used to describe progressiev thinning of hair follciles and only occurs in mpb.

    You arent understanding what minutrisation means. There is no minuturisation going on in the hair cycle. There is only decreased and increased growth/proliferation of hair cells during the different cycles.

    After the telogen cycle - and during the "early anagen" the new hair follcile that is formed in MPB is minutuarised. This is progressive in mpb.

    Stop going on about histogen. Histogen can last forever, if you know your stuff.

    Comment

    • gutted
      Senior Member
      • Jan 2011
      • 1397

      #62
      Originally posted by 2020



      that is the assumption for most of you, but I'm saying no. Why would they be able to regenerate again? PGD2 is still there and it probably supresses all the natural growth factors that your body provides... this is getting hopeless but no one understands me
      this is why i said if you address the inflammation which is why there is elevated pgd2 in the first place the histogen hairs will last forever.

      Comment

      • 2020
        Senior Member
        • Jan 2012
        • 1513

        #63
        Originally posted by gutted
        You arent understanding what minutrisation means. There is no minuturisation going on in the hair cycle. There is only decreased and increased growth/proliferation of hair cells during the different cycles.
        miniaturization, shrinkage whatever. Read this post:
        If it were PGD2 why don't transplanted hairs, or horseshoe hairs, fall out? have they tested bald areas and non-bald areas on the SAME scalp?


        FOLLICLE SIZE naturally changes as it goes from cycle to cycle. DO YOU AGREE?

        Comment

        • 2020
          Senior Member
          • Jan 2012
          • 1513

          #64
          Originally posted by gutted
          this is why i said if you address the inflammation which is why there is elevated pgd2 in the first place the histogen hairs will last forever.
          if you remove PGD2 you would get full regrowth anyways due to your natural growth factors operating as usual without Histogen so I don't see why you would need Histogen at all...

          My point is that Histogen WON'T reverse your MPB but rather just provide your follicles with one last cycle. I wasn't planning on using MPB treatments after Histogen injection so this sucks

          Comment

          • gutted
            Senior Member
            • Jan 2011
            • 1397

            #65
            Originally posted by 2020
            miniaturization, shrinkage whatever. Read this post:
            If it were PGD2 why don't transplanted hairs, or horseshoe hairs, fall out? have they tested bald areas and non-bald areas on the SAME scalp?


            FOLLICLE SIZE naturally changes as it goes from cycle to cycle. DO YOU AGREE?
            dude i dont think im going anywhere with you. Link me to the spurce of that info.

            Comment

            • 2020
              Senior Member
              • Jan 2012
              • 1513

              #66
              Originally posted by gutted
              dude i dont think im going anywhere with you. Link me to the spurce of that info.
              right, so I'm guessing 100% of people didn't know that actual follicle size changes from cycle to cycle... that makes Histogen and all other stimulants useless

              Trusted Board Certified Dermatologists serving Cow Hollow San Francisco, CA. Contact us at 415-907-7354 or visit us at 2001 Union Street, Suite 520, San Francisco, CA 94123: Hair Doc

              Comment

              • Hairismylife
                Senior Member
                • Jun 2012
                • 383

                #67
                Originally posted by 2020
                right, so I'm guessing 100% of people didn't know that actual follicle size changes from cycle to cycle... that makes Histogen and all other stimulants useless

                http://www.hairdoc.com/book/Chapter_...ss_answers.pdf
                That means Histogen-created follicles won't last for long?

                Comment

                • 2020
                  Senior Member
                  • Jan 2012
                  • 1513

                  #68
                  Originally posted by Hairismylife
                  That means Histogen-created follicles won't last for long?
                  exactly one anagen phase. Once it falls out, you will lose it for good. Since ~100 hairs fall out each day, you will lose those 100 hairs permanently.... scientists are ****ing stupid that's all I have to say

                  Comment

                  • ccmethinning
                    Senior Member
                    • Jan 2012
                    • 317

                    #69
                    The histogen charade is over

                    Comment

                    • 2020
                      Senior Member
                      • Jan 2012
                      • 1513

                      #70
                      Originally posted by ccmethinning
                      The histogen charade is over
                      exactly why the **** didn't Spencer ask this question during their 40 minute interview:

                      what makes you think a follicle will start a second cycle after growth factors for the first cycle stop working?

                      I changed my position from optimistic to we're all ****ed...

                      Comment

                      • ccmethinning
                        Senior Member
                        • Jan 2012
                        • 317

                        #71
                        Originally posted by 2020
                        exactly why the **** didn't Spencer ask this question during their 40 minute interview:

                        what makes you think a follicle will start a second cycle after growth factors for the first cycle stop working?

                        I changed my position from optimistic to we're all ****ed...
                        There's still Gho.

                        Comment

                        • Hairismylife
                          Senior Member
                          • Jun 2012
                          • 383

                          #72
                          Originally posted by 2020
                          exactly why the **** didn't Spencer ask this question during their 40 minute interview:

                          what makes you think a follicle will start a second cycle after growth factors for the first cycle stop working?

                          I changed my position from optimistic to we're all ****ed...
                          Aderans still here

                          Comment

                          • Ryan333
                            Junior Member
                            • Jun 2012
                            • 2

                            #73
                            I don't think it's a question of blocking PGD2 completely, it's about stopping it binding to a certain receptor, the receptor that OC000459 targets, so you won't be affecting its positive effects on hair cycling.

                            Comment

                            • neversaynever
                              Senior Member
                              • Dec 2011
                              • 640

                              #74
                              Originally posted by Ryan333
                              I don't think it's a question of blocking PGD2 completely, it's about stopping it binding to a certain receptor, the receptor that OC000459 targets, so you won't be affecting its positive effects on hair cycling.
                              But that doesnt deal with the fact there is excessive PGD2 around balding follicles. So maybe itll help early to moderate baldness. In which case, discussions should halt until people start trying it.

                              There is too much missing pieces to know how long HSC would last. Too be honest, if the price is right, if one HSC treatment buys you at least 2 years...id be happy.

                              And they are getting great results, better than anything we've ever seen in hair loss treatments, so I find it hard to be negative about them.

                              Comment

                              • neversaynever
                                Senior Member
                                • Dec 2011
                                • 640

                                #75
                                Originally posted by neversaynever
                                But that doesnt deal with the fact there is excessive PGD2 around balding follicles. So maybe itll help early to moderate baldness. In which case, discussions should halt until people start trying it.

                                There is too much missing pieces to know how long HSC would last. Too be honest, if the price is right, if one HSC treatment buys you at least 2 years...id be happy.

                                And they are getting great results, better than anything we've ever seen in hair loss treatments, so I find it hard to be negative about them.
                                Unless maybe its that binding to the receptor that causes the malfunction, and pgd2 is over expressed? That would indicate that blocking this receptor is the key!

                                Comment

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