Aderans

[Joker]

Great attitude Desmond and very true!

[2020]

what's the point in making follicles resistant to DHT if you have no hair? Do you really think anyone besides of a couple desperate people from this forum have any interest in that? As I said before, cell based treatments will have a ZERO SUCCESS RATE. Just forget about it. Your only real hope in the next 5 years is Histogen. That's it.

[534623]

https://www.youtube.com/watch?v=l_JHbtXJ0a8

So what exactly is he saying in this scene (10:20 >>>)?

Seems the stuff just works (if at all) for “still not that much AGA-affected hair follicles”.
But in almost slick bald areas = game over (= point of no return) = no rejuvenation of "too dead hair follicles". Sounds logical – is logical.

[ihavebeenchosenithasbegun]

what's the point in making follicles resistant to DHT if you have no hair? Do you really think anyone besides of a couple desperate people from this forum have any interest in that? As I said before, cell based treatments will have a ZERO SUCCESS RATE. Just forget about it. Your only real hope in the next 5 years is Histogen. That's it.

Very interested.

[mjolnir]

what's the point in making follicles resistant to DHT if you have no hair? Do you really think anyone besides of a couple desperate people from this forum have any interest in that? As I said before, cell based treatments will have a ZERO SUCCESS RATE. Just forget about it. Your only real hope in the next 5 years is Histogen. That's it.

1) not everyone is already a NW7
2) not everyone needs to get back to a NW0 to be happy
3) cool science is still cool, regardless of whether it benefits you personally
4) this could be used in conjunction with other treatments
5) it doesn't have a zero success rate because they have pictures of it working. just not quite as well as you'd like.

[Desmond84]

what's the point in making follicles resistant to DHT if you have no hair? Do you really think anyone besides of a couple desperate people from this forum have any interest in that? As I said before, cell based treatments will have a ZERO SUCCESS RATE. Just forget about it. Your only real hope in the next 5 years is Histogen. That's it.

Success rate will be dependent on stage of hairloss and your genetics!

Don't forget the possibility of using Histogen to kick start the follicles and then Aderans to maintain these follicles in the near future!

I just hope Aderans will be available soon! I hate the waiting game

P.S. The 60% response rate was regarding hair regrowth! I wonder how many % maintained their hair?

[Desmond84]

So what exactly is he saying in this scene (10:20 >>>)?

Seems the stuff just works (if at all) for “still not that much AGA-affected hair follicles”.
But in almost slick bald areas = game over (= point of no return) = no rejuvenation of "too dead hair follicles". Sounds logical – is logical.

Yeah I think if you have a small bald spot, you can kind of fix it with hair transplants and Aderans will permanently maintain the hair you have (kind of like Propecia)

[yeahyeahyeah]

1) not everyone is already a NW7
2) not everyone needs to get back to a NW0 to be happy
3) cool science is still cool, regardless of whether it benefits you personally
4) this could be used in conjunction with other treatments
5) it doesn't have a zero success rate because they have pictures of it working. just not quite as well as you'd like.

6) Low norwoods - NW3s can get back down a norwood level or 2 with this.

HT surgeons in turn will be less 'conservative' with their approach - only reason why they currently are, is in case the hairloss progresses.

[JJJJrS]

Call me cynical but this process always seems to repeat itself with these new technologies.

First, the treatment is said to create totally new follicles. When that doesn't prove to be the case, the claim then becomes that it rejuvenates weakened/miniaturized follicles. Finally, they say it prevents the existing follicles from miniaturization. With each claim it becomes more and more difficult to prove.

Don't get me wrong, a side-effect free treatment that prevents the balding process or even slows it down would be a huge deal. All the younger patients in the early stages of baldness would effectively be cured, while those at a more advanced stage would be much more viable candidates for existing surgical treatments. Unfortunately, I'm very skeptical until I see more tangible evidence.

[534623]

Call me cynical but this process always seems to repeat itself with these new technologies.

First, the treatment is said to create totally new follicles. When that doesn't prove to be the case, the claim then becomes that it rejuvenates weakened/miniaturized follicles. Finally, they say it prevents the existing follicles from miniaturization. With each claim it becomes more and more difficult to prove.

Interview with Dr. Washenik in June, 2003:

HS: Can you tell us more about this technique that ARI is currently researching? Does it create a brand new follicle or does it rejuvenate existing dormant or inactive follicles?

Dr. Washenik: Our plan is to create new follicles. We don’t expect to rejuvenate dormant hair follicles, but if that happens, we would be thrilled and that would certainly be a very pleasant surprise.
This may sound like a marketing slogan, but Dr. Lee Bosley often says "hair transplantation is minor surgery but major artistry" because the doctor is deciding where to place the grafts in order to achieve the desired artistic effects.
With tissue engineered hair growth or follicle neogenesis, we are creating a brand new follicle and the onus is on the person implanting the hair seeds to create an artistically acceptable result.
On the contrary,
if old follicles can be rejuvenated, that would be wonderful because we do not have to worry about the hair direction and angle. Everything is already predetermined by nature and we simply have to restart the process. Right now [2003] our focus is creation of new follicles, but I would be thrilled if we can rejuvenate dormant hair follicles too.

Does he sound "thrilled" in the new video?

[mjolnir]

Does he sound "thrilled" in the new video?

As thrilled as anyone does at a medical conference.

The fact is, we can speculate all we like, but that won't actually affect anything. The only reason to check this forum is if you're looking for a bit hope as you come to terms with your condition. So what's the harm in being optimistic?

[2020]

Very interested.

lol then you are one of those desperate forum people who will hang out by this forum for a long time...

Success rate will be dependent on stage of hairloss and your genetics!

Don't forget the possibility of using Histogen to kick start the follicles and then Aderans to maintain these follicles in the near future!

I just hope Aderans will be available soon! I hate the waiting game

P.S. The 60% response rate was regarding hair regrowth! I wonder how many % maintained their hair?

oh god the ignorance here is hurting me...

THINK OF THE AVERAGE HAIR LOSS SUFFERER. Both genders. Don't think of yourself or anyone else from this forum. Most people from this forum(dozens) will take 20 pills in order to grow a couple hair. Billions of people who don't even visit hair loss forums won't. Hair loss is not the end of the world for 95+% people. No one is going to pay thousands of dollars to maintain their bald head. Women(bigger market than men I assure you) don't even need "maintenance" as all of their hormonal disorders that cause hair loss are completely curable but they won't be able to regrow all of their hair. Are you even thinking this through?


This isn't all completely hopeless. Aderans and Replicel are done for sure. They should have never tried treating hair loss using cell based treatments. There is still Histogen which I'm personally giving ~50% chance of it even coming into the market.

[Alf]

OK, i have diffuse hair loss any increase in hair density is welcome and would in fact give me noticeable results.

This was phase 2, why didn't they test if the stuff was compundable? They knew from phase 1 that the patient needs several treatments, so for safety checks shouldn't they check what happens when the patients do in fact get severalt treatments? Same goes for results?

[mjolnir]

lol then you are one of those desperate forum people who will hang out by this forum for a long time...

Do tell us - why are you on this forum?

oh god the ignorance here is hurting me...

THINK OF THE AVERAGE HAIR LOSS SUFFERER. Both genders. Don't think of yourself or anyone else from this forum. Most people from this forum(dozens) will take 20 pills in order to grow a couple hair. Billions of people who don't even visit hair loss forums won't. Hair loss is not the end of the world for 95+% people.

And yet it's still a massive industry.

No one is going to pay thousands of dollars to maintain their bald head.

1) We don't know what the cost will be.
2) Most people don't wait until they're completely bald before getting treatment. Scenario: there's a history of baldness in my family, and I've noticed my crown is starting to thin. I could either get Aderans now, or a hair transplant in a few years. Personally, I'd go for the one that's cheaper, less invasive, and preventative.

Women(bigger market than men I assure you) don't even need "maintenance" as all of their hormonal disorders that cause hair loss are completely curable but they won't be able to regrow all of their hair. Are you even thinking this through?

Don't know enough about pattern baldness in women to comment.

This isn't all completely hopeless. Aderans and Replicel are done for sure. They should have never tried treating hair loss using cell based treatments. There is still Histogen which I'm personally giving ~50% chance of it even coming into the market.

From what I can see, Aderans does just as well as propecia, and while probably more expensive in the short term, could very well be cheaper in the long term (propecia ain't cheap). And cell based treatments are the future of medicine in general, not just hair loss.

I'm going to take a guess that you're a bitter NW7, and I'm sorry you don't appreciate the advances being made here. But just because something is useless for you doesn't mean it's useless for everyone.

[goingquick]

So far all the new treatments seem to be very promising for those in the early stages of diffuse hair loss.

For those of us with slick bald spots, it seems repeating treatments as well as combining different treatments will be necessary. Whether or not that would be any more affordable than a mega-session hair transplant remains to be seen...