Something new?

[Thinning87]

I always find Biologix interesting. Mostly because we've no solid idea about what they're doing, or of their legitimacy.

Also, Dr. Craig Ziering signing on board, their persistence, hm.

But how about all the claims they have made on their website, for example the people they supposedly have cured... this makes no sense!

[clarence]

but at the end of the day, live your lives people, because we aren't getting a new solution on the market for at least 3-4 years, at least one that is FDA approved.

What life...?

[garethbale]

I always find Biologix interesting. Mostly because we've no solid idea about what they're doing, or of their legitimacy.

Also, Dr. Craig Ziering signing on board, their persistence, hm.

wish they would respond to my bloody emails though!

[clandestine]

I always find Biologix interesting. Mostly because we've no solid idea about what they're doing, or of their legitimacy.

Also, Dr. Craig Ziering signing on board, their persistence, hm.

[rdawg]

It may be far off but the more theories and solutions the better.

one of these will hopefully pan out, at least a few of them have shown positive early signs(histogen) but havent been full-blown cures.

the science is being more understood each day.

but at the end of the day, live your lives people, because we aren't getting a new solution on the market for at least 3-4 years, at least one that is FDA approved.

[LMS]

Key points: Preliminary formula to be completed by the end of this year. Final formula to be completed by end of Q1 2014 with the intention to go for FDA, Health Canada and European Medicines Agency approval (start of clinical trials) after that.

Biologix Hair Inc. Releases Research and Development Update on Progress of Beijing Institute of Technology’s Refining and Standardization of Biologix Revive
Toronto, Ontario – June 6, 2013 – Biologix Hair Inc. (OTCBB: BLGX; OTCQB: BLGX) has released a detailed report on the progress of Beijing Institute of Technology toward refining and standardizing Biologix Revive, the basis of the Biologix Hair Therapy System™.

Biologix Hair Science Ltd.™, the wholly owned subsidiary of Biologix Hair Inc. that owns the worldwide intellectual property rights to the Biologix Hair Therapy System™, intends to conduct formal clinical trials and complete other related procedures in order to obtain FDA approval for a standardized "single and shelf-life-stable" formulation of Biologix Revive. In preparation, Biologix Hair Science Ltd.™ contracted in mid-2012 with Beijing Institute of Technology (BIT) (Beijing BIT&GY Pharmaceutical R&D Co. Ltd.) to refine and standardize the Biologix Revive formulation. During the period July 2012 through April 2013 BIT has completed four extensive and significant steps in this process, as follows.

Experiment preparation (July 2012 - December 2012): BIT organised an experienced team of research specialists in order to define the technology needed to perform the work and to design the experiments based on the composition of the formula and the final goal of having the formula in one, possibly two vials. The technology selected to perform these tasks comprises the best available in pharmaceutical laboratories to date and includes the following:

High-performance/pressure liquid chromatography (HPLC) is a chromatographic technique used to separate a mixture of compounds in analytical chemistry and biochemistry with the purpose of identifying, quantifying or purifying the individual components of the mixture. Chromatography identifies components and/or molecules by exposing them to different light wavelengths and, based on the wavelength of the reflected light from each specific molecule, then identifies exactly what molecule is being worked on. This allows the BIT team to identify, separate and study molecules and their interaction with a high degree of precision.
Liquid chromatography–mass spectrometry (LC-MS) is a chemistry technique that combines the physical separation capabilities of liquid chromatography with the mass analysis capabilities of mass spectrometry. LC-MS is a powerful technique used for many applications, which has very high sensitivity (meaning it can work with very small amounts of the molecules being studied) and selectivity (to identify individual molecules that are very like one another). This allows for detection and potential identification of chemicals in the presence of other chemicals in a complex mixture. This is the case with the Biologix Revive formula, which has 24 different molecules working in unison to restart hair growth in dormant hair follicles.
Gas chromatography–mass spectrometry (GC-MS) is a laboratory method that combines the features of gas-liquid chromatography and mass spectrometry to identify different substances within a test sample. GC-MS can identify trace elements in materials that were previously thought to have disintegrated beyond identification. GC-MS is used to perform a specific test, which positively identifies the actual presence of a particular substance in a given sample (whereas a non-specific test merely indicates that a substance falls into a category of substances).
Inductively coupled plasma atomic emission spectroscopy (ICP-AES) is an analytical laboratory technique used for the detection of trace metals and minerals, like those among the 18 minerals in Biologix Revive. This form of emission spectroscopy uses inductively coupled plasma to produce excited atoms and ions that emit electromagnetic radiation at wavelengths characteristic of a particular element. The emission intensity is indicative of the concentration of the element within the sample.
Atomic absorption spectroscopy (AAS) is another laboratory procedure designed for the quantitative determination of chemical elements employing the absorption of optical radiation (light) by free atoms in the gaseous state. This technique is used to determine the concentration of a particular element in a sample to be analyzed, a test that is particularly important in the study of the minerals mixture.
Additionally, the laboratory at BIT is also utilizing the following equipment for their tests and analyses:
Infrared absorption
Ultraviolet absorption
Osmotic pressure
Moore concentration analyzer
Insoluble particles analyzer
Clarity meter
pH meter
Polarimeter, among others
BIT has also acquired all of the chemical reagents that are used to help in the analysis of each of the APIs (Active Pharmaceutical Ingredients) and their respective interactions.

Finally, a series of simulations were run with some of the equipment in order to prepare for the arrival of the APIs and the Reference Standards. Acquisition of the APIs and the Reference Standards is another important investment Biologix has made. The APIs are each of the 24 molecules present in the formula and the Reference Standards are samples of those molecules sold by certified providers which serve as comparison references to compare the actual APIs currently in use to ideal samples of those same molecules.

Preliminary tests (December 2012 – March 2013): After receiving the Reference Standards, the team carried out about 50 preliminary tests, including character, infrared absorption, ultraviolet absorption, pH, osmotic pressure Moore concentration, related substances, assay, etc. and acquired more than 300 basic pieces of data and more than 100 experimental parameters were identified during this phase.

API inspection (February 2013 – April 2013): Since acquisition of APIs, the team has carried out successively more than 100 tests similar to those carried out with the reference standards. However, in addition to the ones mentioned before, particle identification, visible particles measurements, particulate matter determination, heavy metals concentration analysis and related substances analysis have been made. Each of the test items of APIs took four samples, and each of samples was detected 1-5 times. So far, the team has acquired more than 1000 pieces of original data.

Stability of API under high temperature and high light, Biologix Revive formula composition test 1 (March 2013 – April 2013): In this stage the stability of eight kinds of APIs was evaluated under conditions of high temperature and intense light and the main influencing factor in their transformation has been determined. The stability was tested at 0, 5 and 10 days after high temperature and intense light treatment. The parameters analyzed are the ones described previously, and each of the test items required two samples. Each of the samples was detected between one and five times, depending on the API and the results obtained during the initial tests. This degree of repetition and precision greatly increases the likelihood of success. In this phase, more than 600 pieces of original data have been added to the vast amount of data already collected. According to stability data of APIs under high temperature and high light conditions, it is possible to predict the stability of each component after being mixed and accordingly design a formula with the best possible packaging and storage conditions.

Dr. Diego Castresana, Vice President of Research and Development for Biologix Hair Science Ltd.™, summarized: “The significance of the work this BIT team is doing to develop a stable, standardized formulation of Biologix Revive cannot be overstated. It is a critical step on the path to application for FDA approval of the Biologix Hair Therapy System™.

“This progress report from BIT summarizes what I have observed over the last 10 months while receiving frequent updates from the team: Only the highest professional standards have been implemented and requisite attention has been focused on methodology, equipment, materials, method and processes throughout. I am confident BIT will produce a refined, standardized and fully tested formulation of Biologix Revive, with preliminary results expected by the end of this year and the final result by the end of the first quarter 2014, that will allow Biologix Hair Inc. to successfully navigate the application process for approval from FDA, Health Canada, the European Medicines Agency, etc.”

[Thinning87]

And make a complete mockery of every single one of us follicle challenged brothers.

Like I said before, someone needs to call out these fvcking slackers, stand up at the conference and ask a blunt question for a direct answer;

'What good are all of your findings if you in the last 20 years none of you have done anything better than Finasteride and all given us 5+ year timelines with frequent delays? What is stopping any of you from making anything a legitimate commercial product and why isn't anything done to address the roadblocks as is clear by the empty promises and fizzled claims?'

We're all tired of bullshit. You'd think these geniuses with all their supposed knowledge and findings could see the potential to bank on a procedure and make a ton of money off this and better yet, improve the lives of MILLIONS of people worldwide.

What a disgrace.

Come on man we're all pissed but this is not the end of the world. My girlfriend's cousin just found out today she has multiple sclerosis and she's 30 years old. It all happened so fast.

And by the way I found a girlfriend despite having shaved my head to a one 3 months ago and showing visible thinning (the secret is indeed not giving a **** and making sure who's around you knows that you don't... it's that simple!).

And if you don't feel better yet, look at all the positive news! We might just be nearer than we think... personally if someone asked me if I could live the next ten years bald and then have a cure for sure, I'd take that and get my hair back at 35.
And I think it's definitely possible something might happen within this time frame... look at all the presentation abstracts! I mean with all these scientists playing around with stem cells and follicles, something's gotta lead us somewhere right? Am I really that optimistic if I say that?

[hellouser]

they'll probgabaly give us some 6 year roadmap...

And make a complete mockery of every single one of us follicle challenged brothers.

Like I said before, someone needs to call out these fvcking slackers, stand up at the conference and ask a blunt question for a direct answer;

'What good are all of your findings if you in the last 20 years none of you have done anything better than Finasteride and all given us 5+ year timelines with frequent delays? What is stopping any of you from making anything a legitimate commercial product and why isn't anything done to address the roadblocks as is clear by the empty promises and fizzled claims?'

We're all tired of bullshit. You'd think these geniuses with all their supposed knowledge and findings could see the potential to bank on a procedure and make a ton of money off this and better yet, improve the lives of MILLIONS of people worldwide.

What a disgrace.

[Thinning87]

they'll probgabaly give us some 6 year roadmap...

[hellouser]

Biologix are presenting their results at the world congress next month.

Might be interesting.

Ou, that sounds promising... definitely something that may give them credibility.

[Thinning87]

very surprising... let's unleash Desmond's research fury and find out what they say at the congress

[gladiator]

Biologix are presenting their results at the world congress next month.

Might be interesting.

[LMS]

Seems so, doesn't it? But how do you determine prestige?

In research, prestige comes from publications (especially in known/respectable journals). I as a grad student have more publications than all these guys at Biologix put together. The vast majority of them are businessmen, not scientists or clinicians. The few that have published clinical work are tag-along authors, not principal investigators or primary authors. Credibility-wise, that's really really bad.

In medicine there is a significant intellectual rift between bona fide physician scientists and GPs/PCPs. The latter make the money and retire, but the former contribute to science and are remembered forever. Biologix has no physician scientists.

Ok, maybe I used the wrong word. Not really looking to get into an arguement/debate. But regardless, all I'm saying is that having people like Ziering join Biologix does add some credibility in MY eyes.

But anyways - I was more interested in the second part of my post about the BIT and their r&d deal.

[paradigmshift]

Seems so, doesn't it? But how do you determine prestige?

In research, prestige comes from publications (especially in known/respectable journals). I as a grad student have more publications than all these guys at Biologix put together. The vast majority of them are businessmen, not scientists or clinicians. The few that have published clinical work are tag-along authors, not principal investigators or primary authors. Credibility-wise, that's really really bad.

In medicine there is a significant intellectual rift between bona fide physician scientists and GPs/PCPs. The latter make the money and retire, but the former contribute to science and are remembered forever. Biologix has no physician scientists.

[LMS]

Thought I might update this:

TORONTO, ONTARIO--(Marketwired - April 24, 2013) - Biologix Hair Inc. (OTCBB:BLGX) (OTCQB:BLGX) is pleased to announce the appointment of Arthur G. Handal M.D., F.A.C.S. to the Company's Medical Advisory Board.
Certified by the American Board of Plastic Surgery, Dr. Arthur G. Handal's interest in plastic/cosmetic surgery began at the Chicago/UHS Medical School and became focused during his residency at State University New York. Handal gained early acceptance into the SUNY/Kings County Medical Center and upon completion of his residency, he continued surgical training with prestigious fellowships in aesthetic surgery in association with the University of Miami and hand surgery at Hartford Hospital in Connecticut. For more than 20 years, Dr. Handal has dedicated his practice to aesthetic plastic surgery.
Dr. Handal's private, professional Sanctuary Surgical Center, affiliated with the Boca Raton Community Hospital offers surgery and pre- and post-operative care in a state of the art, fully licensed facility accredited at the highest level as an ambulatory surgical center, and offers a full range of aesthetic services.
He is a member of the American Society of Plastic Surgeons, American Society for Aesthetic Plastic Surgery, American College of Surgeons, Southeastern Society of Plastic and Reconstructive Surgeons, Palm Beach County Society of Plastic and Reconstructive Surgery Florida Medical Association, Palm Beach County Medical Society and the American Society of Laser Medicine and Surgery. Dr. Handal offers cutting-edge techniques and innovations to his patients, developed through attending the major professional meetings several times a year.
Dr. Arthur Handal commented, "I am pleased to become part of the Biologix Hair Inc. team by serving on its Medical Advisory Board. The ongoing R&D efforts being undertaken by Biologix with the Beijing Institute of Technology and level of professionalism with which the Company is working toward application for regulatory agency approval is a smart strategy. I am particularly impressed with the attention being paid to developing an international distribution channel of licensed clinicians and medical practitioners in advance of FDA approval thereby readying Biologix to penetrate the global market potential for its Biologix Hair Therapy System™."
Ron Holland, Biologix Hair Inc. CEO and Director, welcomed Dr. Handal, commenting: "Dr. Handal's experience and knowledge are of vast benefit to Biologix and we are grateful he's consented to serve on the Biologix Medical Advisory Board. As we further build out the global network of clinicians who wish to become Certified Biologix Hair Therapists™ as well as maintain our ongoing R&D efforts, the advice offered by members of our Medical Advisory Board will be integral to our continuing development. We welcome Dr. Handal to the Biologix team."

It seems another fairly prestigious doctor has become a part of Biologix...


Anyways, what I found more interesting is this piece which I found while trying to do more research on what exactly biologix is doing in Beijing

http://www.biologixhair.com/default/assets/File/BiologixHairInc-ReviveReagent.pdf

If you don't want to read it all - basically the research and development going on at the Beijing Institute of Technology is making the formulation more stable as previously, during trials in South America it was mixed on the spot (a total of 7 ingredients). They're working on making a formulation with all 7 ingredients and making it stable for atleast 6 (preferably 12 months) in various conditions. Furthermore they're looking to change the PH of it as to not cause any discomfort during injections (one can only assume that might've been a problem in the South American trials). Naturally, they don't let us know any of the ingredients save for one, which is Biotin.

Anyways - the Research & Dev was set to take 14 months. The report was published in April 2012. So assuming thats when research started, they should be wrapping up sometime June of this year. However, we have no idea when R&D actually started so it's pure speculation.

It couldve been June or July 2012 or even later for all we know:

http://www.biologixhair.com/investors/biologix-news/biologix-hair-science-ltd-signs-rd-agreement-with-beijing-institute-of-technology/

http://www.biologixhair.com/investors/biologix-news/biologix-hair-science-ltde284a2-makes-us-525000-payment-on-rd-partnership-agreement-with-beijing-institute-of-technology/