Histogen Update - Spencer Kobren Speaks With Dr. Craig L. Ziering

[Jcm800]

Hey UK how's the Minox going? Been on it some time now, if still using it?

[UK_]

so we're stuck with those two dinosaurs.

Lol yeh an one of them's a T-Rex that'll bite off yr dick if you're lucky enough.

I always thought Bimatoprost works in the same way as Minox - does it force hairs to shed initially like minox?

[Pate]

Latanoprost is an older drug than bimatoprost, in fact the patent has already expired so it's available generic.

Latanoprost is also, I believe, the drug that was tested on macaque monkeys with MPB, some years ago now.

It's one of those drugs that's been around for years and but never made it on to the market for MPB, presumably because of the belief its effectiveness is limited and it would cost too much to get it through trials.

One of the depressing, constant themes of hair loss drug development. So many drugs offer more potential than minox or fin but are never developed for commercial reasons, so we're stuck with those two dinosaurs.

Hopefully the bimatoprost results are positive and Allergan rush to Phase III, knowing they will have Histogen breathing down their necks. I personally believe bimatoprost is the only new treatment we've got a chance of seeing this side of 2015.

[PinotQ]

I believe latanoprost is a similar but less effective type of prostaglandin analogue. I don't believe Dr. Bernstein is working with Allergan. This approach would appear to be consistent with recent research findings regarding PGD2.

[neversaynever]

Here's a postive development from Allergan: http://www.bernsteinmedical.com/hair...ss-medication/

Overall increase in hair density (unclear how they define hair density) 22% in 50% of participants in 24 weeks.

Obviously, this is already FDA approved and on the market but it could become less expensive and more practical as a hairloss treatment in a relatively short period of time.

whats the difference between latanoprost and bimatoprost? Are there currently two seperate studies being done on them?

http://www.clinicaltrials.gov/ct2/show/NCT01325337?term=Allergan+and+bimatoprost&rank=7

Is bernstein working with allergan?

The other study is with 600 people, gender split.

http://www.cbsnews.com/8301-505123_162-42849516/allergans-potential-baldness-cure-clears-one-hurdle-heads-for-the-hard-part/

[PinotQ]

Here's a postive development from Allergan: http://www.bernsteinmedical.com/hair...ss-medication/

Overall increase in hair density (unclear how they define hair density) 22% in 50% of participants in 24 weeks.

Obviously, this is already FDA approved and on the market but it could become less expensive and more practical as a hairloss treatment in a relatively short period of time.

[mjolnir]

I do have to say, $5k is nearing the upper limit of what my vanity is worth to me. If nothing else though, it's good to know that I would be able to afford it if I absolutely needed to. Honestly, I'm really hoping that in two or three years, or whenever this actually ends up being available, I'll have finally gotten used to the idea of being bald.

[mlao]

dont bother asking, he adds 5 years every time he posts something

There really should be a like button on this forum

[yeahyeahyeah]

tbh this pdf is out of date, they may change the price of the procedure later on

[tizzle]

dont bother asking, he adds 5 years every time he posts something

[2020]

shhhh

all we can do is wait until 2025 to find out


until then we should do our best to hate on gho and promote rassmusen

explain how you came up with that number(2025).

[NeedHairASAP]

Hmm.

Well $5k is not an astronomical amount of money in it's own. The question is, what is priced that way? In this case it's an injection. And, this is an injection that it's not crystal clear if it will give us the amount of coverage a current hair transplant will give us. So it's cheaper than a hair transplant, but it's probably cheaper for a reason.

shhhh

all we can do is wait until 2025 to find out


until then we should do our best to hate on gho and promote rassmusen

[PatientlyWaiting]

I just found this on their investors document:

http://www.histogen.com/downloads/hi...orinvestor.pdf [Page 16]



apparently it will be even cheaper than a hair transplant...

Hmm.

Well $5k is not an astronomical amount of money in it's own. The question is, what is priced that way? In this case it's an injection. And, this is an injection that it's not crystal clear if it will give us the amount of coverage a current hair transplant will give us. So it's cheaper than a hair transplant, but it's probably cheaper for a reason.

[john2399]

How many injections per procedure ? is it how many as it takes?

[Smiley]

hmm 5 thousands bucks for a single procedure is not so cheap if you ask me. It depends mainly on how long the effects would last, and how significant the cosmetic results would be. If the effects would last at least 5 years, then it would be a decent price. If shorter, I don't know...

I guess that would be the question. 'How long would it last?'

But that is definitely a decent price. Might be a long waiting list to get an appointment for a procedure at that price point.