Where are the phase IIb results for Bimatoprost?

[Hairismylife]

The result is so far so good.
Anyone knows the timeframe of it?
This regrowth from 1 month or from 1 year usage has big different meaning.

[Occulus]

Not good - definitely not a major improvement over minoxodil, and several years away.

Back to the drawing board.

[Swooping]

One question. They mention;

Ph 1 PK & Ph 2b studies planned Q1 2016

I don't understand the "Ph 1 PK" part. I assume "PK" stands for pharmacokinetics? Anyone know this?

[Swooping]

I think it's bad. It would be good 10-15 years ago though. Reason why is that it seems to be pretty much equal to minoxidil 5%. While bimatoprost 3% seems to win barely from minoxidil 5% in the expert panel review and global assesment the subject self assesment seems to favour minoxidil 5% (by almost nothing though).

HOWEVER minoxidil has to cope with the fact that many people don't respond to minoxidil at all because of the lack of sulfotransferase. Also if that is the best picture they have to show then that's not good.

Well up to another phase 2 clinical trial to see if the "enhanced" formulation can bring better results!

Do we have more data? Side effects and such?

SM04554 please surprise us.

[JayM]

Plus they have said re doing a phase right? Maybe they plan to add with Seti maybe? Those results aren't bad though for 1% and without reducing pgd2/DHT.

Good signs for the people doing group buys for pge2 for sure. Really solid.

[Keki]

Not bad at all, now we need to know what are the sides, the hair shaft sincro like minox and his shedding, the blood pressure drop and the cost, i think it will be expensive as ****

[It's2014ComeOnAlready]

Well, it works better than minox, but it appears to have hit some snags.

info on page 16 of the PDF

http://ir.allergan.com/phoenix.zhtml?p=irol-eventDetails&c=65778&eventID=5206702

[champpy]

hey 2014, is that responder rate you mentioned on eyelashes? Or did you see a study of it helping here in other places?

[It's2014ComeOnAlready]

Well I appreciate you sharing your experience, it's just anecdotal evidence and doesn't mean a whole lot. Some of the participants in studies had no results as well, but others had good results. Ditto for minoxidil.

I don't think anyone is expecting this to be a cure. I'm just expecting something more potent than minoxidil, but it's not going to work for everyone.

Latisse has a responder rate of 85%-90%. I think unless your hair loss is too aggressive, most should see an effect.

[unbalding]

Because i used latisse and another off brand for 6 months on one spot near my temples. Guess how many new hairs grew? Not one

Well I appreciate you sharing your experience, it's just anecdotal evidence and doesn't mean a whole lot. Some of the participants in studies had no results as well, but others had good results. Ditto for minoxidil.

I don't think anyone is expecting this to be a cure. I'm just expecting something more potent than minoxidil, but it's not going to work for everyone.

[champpy]

Because i used latisse and another off brand for 6 months on one spot near my temples. Guess how many new hairs grew? Not one
Let me add, i was also dermastamping the area also to help penetration. Nada man. Only reason i can think of is the aga is outweighing the effects of bim somehow

[unbalding]

If its not hair related im not sure why they would do a presentation at the congress.... but again im very certain this can help existing hair thats not threatened by AGA, but i dont see it regrowing anything. Just my opinion though

I don't understand why people say this. At lower concentrations it was similar to minoxidil, so we already know that it regrows hair. The question is how much?

[champpy]

If its not hair related im not sure why they would do a presentation at the congress.... but again im very certain this can help existing hair thats not threatened by AGA, but i dont see it regrowing anything. Just my opinion though

[It's2014ComeOnAlready]

Regarding the funded study...I think it's good that Allergan is paying to get more info on the effect of this drug on the scalp. That particular study doesn't look like it's the AGA one, however. It's a study on sebaceous glands and the drug, not hair growth and the drug. Could just be a supplemental study, either way, it's good.

[BrianH123]

I'm becoming bipolar... Every other comment is either optimistic/positive , or negative .. God I can't take the swings , it's never a good way to start or end the day reading these forums lol