follicept - what's this?

[tf2legend]

I just read the IGF-1 summary on the follicept website.

"©2014 Prometheon Pharma,LLC

TransdermalDelivery of IGF-1 and DHT for MPB

Grant Mangleburg

Background

"Androgenic alopecia, or male pattern baldness (MPB) is a condition that affects up to 70% of men at some point during their lives. The condition is characterized by below-normal levels of androgens such as dihydrotestosterone (DHT), testosterone, FSH, and sex hormone binding globulin at the dermal papillae."

Shouldn't that say "above-normal levels" instead?

Just thought I'd point that out

[tf2legend]

This is the next paragraph:

"Review of Disease Mechanism and Therapeutic Approaches

Research on restoration of hair follicle function in individuals with MPB has centered largely around restoring normal levels of the androgens listed above. However, these efforts have not resulted in any efficacious treatments that are widely marketable."

??

[RU58841]

Hey Devon, quick but important question for you (sorry if this was already answered):

I think I read earlier that people would have to stop Minoxidil while using Follicept, because the use of Follicept would make Minoxidil be absorbed to a dangerous degree (if I remember right).

I'm guessing this applies to all topicals being used on the scalp then? Like RU, Spiro cream, OC, etc.?

[BoSox]

God, please let this work on the hairline. Please.

I've lost about 1cm of hairline/temples and I don't think fin will recover it. I've been praying day and night over the past year for something to come out of nowhere, something that I could apply to my head and revive dormant follicles, something that wouldn't even need FDA approval. And here comes Follicept. I always believed this was possible, we just don't know what to deliver and how. It makes sense that a miniaturized follicle can become "maximized" again. I have faith in this. The science looks good.

I'm with you man! I have enormous faith in this. Praying.

[hairderp]

Dont have faith in anything before you see some proof!!!!!!

[KJ1982]

This is all so very, very exciting; the most noticeable area of loss for me is my hairline so if this has any chance of restoring it to its former glory then consider me stoked for results!

Here's hoping that the science pans out in our favour...

[Jagger]

Dont have faith in anything before you see some proof!!!!!!

That's like, the opposite of how faith works.

[stayhopeful]

That's like, the opposite of how faith works.

Dammmmm +1 +1

[tf2legend]

I'm with you man! I have enormous faith in this. Praying.

Same here. I'm on my knees every night

[BiqqieSmalls]

PLEASE LET FOLLICEPT RUN THEIR TRIALS BEFORE WE TALK BACK UP PLANS.

Again, if they can deliver IGF-1, there may be no need for fin/minox/keto.... that would be like suggesting you take a road trip to the destination that you're already standing at.

What about Minoxidil dependent hairs?

[NOhairNOlife]

Dont have faith in anything before you see some proof!!!!!!

That's like, the opposite of how faith works.

Lol... I was thinking the same thing. +1 on the reply.

Even if this doesn't work, the fact that we have something that could come to market in a few months is exciting enough

[BiqqieSmalls]

I just read the IGF-1 summary on the follicept website.

"©2014 Prometheon Pharma,LLC

TransdermalDelivery of IGF-1 and DHT for MPB

Grant Mangleburg

Background

"Androgenic alopecia, or male pattern baldness (MPB) is a condition that affects up to 70% of men at some point during their lives. The condition is characterized by below-normal levels of androgens such as dihydrotestosterone (DHT), testosterone, FSH, and sex hormone binding globulin at the dermal papillae."

Shouldn't that say "above-normal levels" instead?

Just thought I'd point that out

Can anyone confirm if this is true?????????

[follicept]

You guys are funny. I am nervous and excited too! Can't wait. As for other therapies in conjunction: We have not studied Follicept used in combination with any hair grower. Therefore, the answer is: We don't know. Follicept was developed as a stand alone first-line therapy. Based on potential side effects from enhanced delivery, we can not recommend you continue other therapies. We are hopeful this should be effective enough on its own. Keep the good vibes comin! I have been losing my hair over trying to work on all this hair growth stuff

[Hemo]

Devon, the first part of your post (above) is a reference to the issue I raised about how it seems somewhat out of the ordinary for Follicept to accept assistance from regular-Joes at a hair website in locating a chemical agent for clinical testing. The fact that this was the first issue you addressed shows that you understand that my issue is a reasonable issue. Thanks for addressing the issue. I'm not saying I think your response satisfies my concern 100% but at least I do have your response now. This issue on its' own would not prompt me to think that there is wrongdoing going on Follicept, but I want you to know that I am keeping score to see if there's an increase in peculiarities. That aside, I do kind of think there is some validity to your point because you are a tiny company and a new company so I can understand somewhat why your situation is different from say Merck or Glaxo.

That aside, I definitely think you should offer a chance to get stock at a good price since we are actually involved in helping you with the project. If you have actually found a cure for hair loss there will be lots of money made off of that. More money than the few of you at your company could spend in 10 lifetimes.

Ha, first you offer a threat that you'll be looking out for "peculiarities" and then ask for discounted stock for looking for a supplier, only to follow up with a critique of the IGF-1 that they ordered...you sound a little delusional. Why don't you leave those types of evaluations to the medical professionals that are doing the research? You sound like the type of person that shows up to a lecture and argues with the professor the whole time.

[follicept]

Ha, first you offer a threat that you'll be looking out for "peculiarities" and then ask for discounted stock for looking for a supplier, only to follow up with a critique of the IGF-1 that they ordered...you sound a little delusional. Why don't you leave those types of evaluations to the medical professionals that are doing the research? You sound like the type of person that shows up to a lecture and argues with the professor the whole time.

Well said. Is an effective product not enough? We really would love to be able to offer stock, but the SEC makes that impossible. Sorry!