Bimatoprost finishing up Phase IIb trial!

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  • PinotQ
    replied
    Originally posted by It's2014ComeOnAlready
    Regardless, I saw that Dr. Alan Bauman had been getting results all over the top of the scalp with bim (although I'm not sure of the concentration he was using). So, if you've still got some thinning spots while on fin, you could probably take care of those. If a PGD2 inhibitor comes on the market sometime, and you've got bim, you're looking at one of the best things to happen for guys with hair loss, maybe ever. If you've started thinning, or have been for a couple of years, it can be reversed with these drugs. I just hope Cots an Follica hurry the hell up.
    I agree that could be a great combination. My understanding is that bim does directly what minox does indirectly........which is why it is more powerful. I actually tried Lumigen for a while. I saw some noticeable results (with just 4-6 drops daily) in less than 2 months in my crown (my thinnest area) but they faded. This was very expensive at Lumigen pricing.

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  • It's2014ComeOnAlready
    replied
    Regardless, I saw that Dr. Alan Bauman had been getting results all over the top of the scalp with bim (although I'm not sure of the concentration he was using). So, if you've still got some thinning spots while on fin, you could probably take care of those. If a PGD2 inhibitor comes on the market sometime, and you've got bim, you're looking at one of the best things to happen for guys with hair loss, maybe ever. If you've started thinning, or have been for a couple of years, it can be reversed with these drugs. I just hope Cots an Follica hurry the hell up.

    Leave a comment:


  • PinotQ
    replied
    Originally posted by It's2014ComeOnAlready
    I hadn't been following it either (mostly because I'm more interested in a better fin alternative). But, I've been getting some really good news about bim, and because it inhibits PGD2, that makes me even more excited because I'm hoping something pans out with Follica and PGD2/GPR44 inhibitors.
    FYI I think bim has promise but I don't believe bim inhibits PDG2 as it is a PDF2 analog which promotes the activity of PGE2 which stimulates hair growth. Here is a good summary: "It is more likely that a number of end factors contribute to hair loss with factors like PGD2 inhibiting hair growth and others such as PGE2 and PGF2 promoting it," he said. "PGD2 inhibition may emerge as part of a combined approach used in combination with agents that work via different mechanisms . . . as a more effective approach to hair loss treatment." http://health.usnews.com/health-news...ainst-baldness

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  • beetee
    replied
    If anything comes out in the future, I hope it's good enough that fin/minox aren't even in the discussion. When people say that "potential product x" is better than either it makes me nervous, as I basically don't consider either to be a treatment. The fact that they have the sales that they do to me is proof of just how desperate people are for something, even if that thing barely works (if at all) for most most people.

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  • unbalding
    replied
    Originally posted by FearTheLoss
    You can use it now at like 5% for $70 a month.
    From where? I will buy it today, and report the results here.

    Leave a comment:


  • It's2014ComeOnAlready
    replied
    I hadn't been following it either (mostly because I'm more interested in a better fin alternative). But, I've been getting some really good news about bim, and because it inhibits PGD2, that makes me even more excited because I'm hoping something pans out with Follica and PGD2/GPR44 inhibitors.

    Leave a comment:


  • FearTheLoss
    replied
    Oh wow, that's great to hear. I haven't been following bim much, but I've heard from a few doctors that they've seen some results with it.

    Leave a comment:


  • It's2014ComeOnAlready
    replied
    No, the results of the study won't be posted until January. The 2nd phase of the study is complete.

    Leave a comment:


  • FearTheLoss
    replied
    Originally posted by It's2014ComeOnAlready
    He said that he'd been hearing that the results from the phase IIb bim study had excellent results, superior to minoxidil, and would have some people coming off Propecia and minoxidil to use it instead. Spencer actually said that he'd been hearing the same as well. However, the facts are only that Johnson and Johnson was at one point looking to buy Allergan (around April), but it didn't pan out. As we know also, Valeant was trying to buy Allergan, but that didn't happen, and yesterday Actavis did.

    Actavis stated in the buyout that they believe that with this combination, they'll become a top-10 pharmaceutical company. Allergan's biggest revenue maker is botox at this point, and there is nothing in their pipeline that looks like it could be extremely popular or a cash-cow. Actavis purchased the company for 13 billion more than anyone else was willing to offer at $219 a share, and the stock even jumped.

    Something's going on, yet it's easy to be doubtful until those results are posted.
    How would they hear that? I thought the phase 2 study isn't supposed to be finished until January?

    Leave a comment:


  • cocacola
    replied
    Its seems we have some finance savy people on this forums!

    It would really be great if what you guys are saying about phase 2 results is true.
    The hairloss market potential is huuuuge, anyone who comes up with even half of "the cure™" is going to make billions.

    For myself minox worked very well for a certain period of time then results deteriorated. Also i had side effects from it. Therefore if it is at least as good as minox its a great addition to anti baldness arsenal.

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  • It's2014ComeOnAlready
    replied
    He said that he'd been hearing that the results from the phase IIb bim study had excellent results, superior to minoxidil, and would have some people coming off Propecia and minoxidil to use it instead. Spencer actually said that he'd been hearing the same as well. However, the facts are only that Johnson and Johnson was at one point looking to buy Allergan (around April), but it didn't pan out. As we know also, Valeant was trying to buy Allergan, but that didn't happen, and yesterday Actavis did.

    Actavis stated in the buyout that they believe that with this combination, they'll become a top-10 pharmaceutical company. Allergan's biggest revenue maker is botox at this point, and there is nothing in their pipeline that looks like it could be extremely popular or a cash-cow. Actavis purchased the company for 13 billion more than anyone else was willing to offer at $219 a share, and the stock even jumped.

    Something's going on, yet it's easy to be doubtful until those results are posted.

    Leave a comment:


  • beetee
    replied
    Originally posted by It's2014ComeOnAlready
    If any of you guys caught the latest bald truth radio show (it's been posted on youtube), Joe from SI called in and was very excited about bim, he seems to believe that the results of the phase IIb study is in part a big reason why allergan was bought by actavis. I agree with him, because it makes sense. If it far superior to minox, then bim will take over the market share of minox (guaranteed revenue). I personally have never used minox because the results were never that impressive, and to have to keep buying it is just ridiculous. 1/3 of the revenue coming in for allergan is from botox, and now just imagine a superior product to minoxidil that both men and women can use, it will make billions annually.

    We know that bim inhibits PGD2, and according to Cotsarelis, PGD2 is what inhibits hair growth. It works amazingly on eyelashes, we know that. I think all of these developments are not coincidence, and everyone should be really excited about this.
    Did Joe give reasons or evidence to support this or did he just think it would make sense that that's why they were interested in Allergan?

    Leave a comment:


  • ChemicalBrother
    replied
    there was some talk here about iris pigmentation being a side effect of bimatoprost.

    But now I read that they (Allergan) is actually in Phase2 trials for using Bimatoprost INSIDE the eye (through an implant , but also topically):

    Allergan has reviewed data from its Phase 2 clinical trials of bimatoprost sustained-release implant for the treatment of elevated intraocular pressure and glaucoma. Patients in this trial received a bimatoprost sustained-release implant in one eye and topical bimatoprost in the contralateral eye.

    Leave a comment:


  • It's2014ComeOnAlready
    replied
    If any of you guys caught the latest bald truth radio show (it's been posted on youtube), Joe from SI called in and was very excited about bim, he seems to believe that the results of the phase IIb study is in part a big reason why allergan was bought by actavis. I agree with him, because it makes sense. If it far superior to minox, then bim will take over the market share of minox (guaranteed revenue). I personally have never used minox because the results were never that impressive, and to have to keep buying it is just ridiculous. 1/3 of the revenue coming in for allergan is from botox, and now just imagine a superior product to minoxidil that both men and women can use, it will make billions annually.

    We know that bim inhibits PGD2, and according to Cotsarelis, PGD2 is what inhibits hair growth. It works amazingly on eyelashes, we know that. I think all of these developments are not coincidence, and everyone should be really excited about this.

    Leave a comment:


  • beetee
    replied
    Originally posted by Pelopeleon
    So, Do you think we will be able to buy bimatoprost x% from Asia markets in 2015?
    That I have no idea about. I'm just keeping my eye on the company and their potential product.

    Leave a comment:

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