We have a vehicle for CB-03-01: VERSAPRO

[burtandernie]

How do we really know what CB does or how powerful it is from that preliminary phase 1 study? I mean the 2x 5% might give results that are a lot different. I mean I dont know how anyone knows from such a small amount of data how well it works or how powerful it is in relation to say propecia.
They got good results in that study with the 1 percent in relation to the ciproterone-acetate or 1% 17alpha-estradiol. So who really knows how it does at 5 percent applied more frequently. They are also switching vehicles which will probably weaken it but they can play around with that and see if they can get it to work better. Way too early to say IMO. To me this is still the nearest and most promising thing even if its another AA so its not going to cure MPB Or anything

[Tenma]

Maintenance is already possible today with the current treatments we have, and CB isn't going to do a better job at it, it's the cold truth. Heck I'll tell you now that DUT and RU will outperform CB-03-01. RU surely is a stronger compound. The % of people with side effects with current treatments is small anyway, and while YOU might care because you are in this position. These companies don't give a damn, they only care about ROI.

Cosmo played a nice sugarcoating game with their phase 1 concept of trial too btw. Make a concept proof of trial with 1x a week CB administration, publish huge results but opt for 2x a day application of a 5% formulation in the 2nd phase LOL. Yeah, mark my words. This one isn't going to pull through . They are 10 years to late. Lovely financial games too.

All you said is true but remember RU isnt widely available for everyone. Here in Argentina we cant buy "research chemicals" so easily and is my understanding most countries in Latinoamerica are in the same situation.

The advantage Cosmo Pharmaceuticals has over whichever was developing RU is the extension of the patent. They have exclusive rights on CB till 2030

[Swooping]

Minoxidil is used twice a day, i dont know how it's inconvienent to use a drug much more powerful than DUT/FIN without the side effects? takes you all of 5 minutes to use this stuff.

RU has side effects and is more complicated to use in the greymarket.

CB will become the new FIN and if it can be sold over the counter like Rogaine then it will be huge. and i've never seen a company not release great product because another product 'might' come out within a few years after, that's nonsense. Look how fast they are trying to get the acne version released and look how much competition there is in that market!

Sure a better cure might come out in 5-10 years, but its a ways away. Maintanence is key right now and is a possibility TODAY with stuff like CB.

First of all it's not even much more powerful than finasteride who told you that? Not even to speak of dutasteride, as that almost peaks the ceiling together with RU for example. Only castration would be better or having a super-antagonist, but CB is far from being that. So forget about CB doing a better job in terms of efficiency than the current treatments we have now. Meaning the only unique selling point of CB-03-01 would be that it is supposedly devoid of side-effects. You already believe it is actually devoid of side effects. Based on what actually?

Maintenance is already possible today with the current treatments we have, and CB isn't going to do a better job at it, it's the cold truth. Heck I'll tell you now that DUT and RU will outperform CB-03-01. RU surely is a stronger compound. The % of people with side effects with current treatments is small anyway, and while YOU might care because you are in this position. These companies don't give a damn, they only care about ROI.

Cosmo played a nice sugarcoating game with their phase 1 concept of trial too btw. Make a concept proof of trial with 1x a week CB administration, publish huge results but opt for 2x a day application of a 5% formulation in the 2nd phase LOL. Yeah, mark my words. This one isn't going to pull through . They are 10 years to late. Lovely financial games too.

[Gjm127]

Minoxidil is used twice a day, i dont know how it's inconvienent to use a drug much more powerful than DUT/FIN without the side effects? takes you all of 5 minutes to use this stuff.

RU has side effects and is more complicated to use in the greymarket.

CB will become the new FIN and if it can be sold over the counter like Rogaine then it will be huge. and i've never seen a company not release great product because another product 'might' come out within a few years after, that's nonsense. Look how fast they are trying to get the acne version released and look how much competition there is in that market!

Sure a better cure might come out in 5-10 years, but its a ways away. Maintanence is key right now and is a possibility TODAY with stuff like CB.

well said, I doubt Cosmo is looking at Histogen and Replicel and saying, oh well, they got it, let's let it go... It's going to be a huge market just like acne and competition will be key. Acne market has hundreds of approved products, some working better than others like Accutane, etc... But you still have other products on the market, and others pending approval...

[rdawg]

Chuckling here.. As expected obviously there was never a vehicle problem, but the concentration was. Sad that most of the baldies are so hopeful that they neglect the facts. Anyway 2 x 50mg a day is even more than I expected and kinda confirms the fact that RU58841 is stronger pound for pound than CB-03-01 together with the studies that are out.

2 x a day by the way is extremely stupid in my opinion btw. We are talking about convenience here. To be honest I don't see CB-03-01 for AGA going to hit the market now, mark my words lol. It's just a financial game played now.

Reason? They are way to late. If CB-03-01 were to be released realistically let's say in 2017-2018 they would only have MAX. a couple of years of revenue. Heck I would even say less than 5 years of revenue. Simply because over 10 years we'll definitely have more exciting things. It will be way outdated by then, and frankly it already is because we already have FIN/DUT/RU. NEXT.

Minoxidil is used twice a day, i dont know how it's inconvienent to use a drug much more powerful than DUT/FIN without the side effects? takes you all of 5 minutes to use this stuff.

RU has side effects and is more complicated to use in the greymarket.

CB will become the new FIN and if it can be sold over the counter like Rogaine then it will be huge. and i've never seen a company not release great product because another product 'might' come out within a few years after, that's nonsense. Look how fast they are trying to get the acne version released and look how much competition there is in that market!

Sure a better cure might come out in 5-10 years, but its a ways away. Maintanence is key right now and is a possibility TODAY with stuff like CB.

[Gjm127]

I haven't tried any treatment myself, I'm just on Resveratrol and Green Tea extracts once daily.

My hair loss started when I was 19 in the temple region up until I was 22 and then I started losing in density in the frontal region. As of today, I'm 23 and my temportal region has started to recede again as density continues to decrease in the front and temple regions.

I seem to have the same pattern loss as my mother's side, they just have extremely receded temples until their mid 30's and then their frontal regions lost between 35 and 45.

I'm an extreme hypocondriac so I'm scared of using FIN. My dad was on minoxidil all his life from his 30s, seemed to help a bit but he had huge dark circles and bag requiring him to do surgery afterwards so I don't want to hop on minox.

What do I do? Do I have hope for this? or SM? I don't know how long I have left to keep my hair that's still manageable till now, feeling like this time is almost ending.

[Kudu]

Chuckling here.. As expected obviously there was never a vehicle problem, but the concentration was. Sad that most of the baldies are so hopeful that they neglect the facts. Anyway 2 x 50mg a day is even more than I expected and kinda confirms the fact that RU58841 is stronger pound for pound than CB-03-01 together with the studies that are out.

2 x a day by the way is extremely stupid in my opinion btw. We are talking about convenience here. To be honest I don't see CB-03-01 for AGA going to hit the market now, mark my words lol. It's just a financial game played now.

Reason? They are way to late. If CB-03-01 were to be released realistically let's say in 2017-2018 they would only have MAX. a couple of years of revenue. Heck I would even say less than 5 years of revenue. Simply because over 10 years we'll definitely have more exciting things. It will be way outdated by then, and frankly it already is because we already have FIN/DUT/RU. NEXT.

Fair enough, I still hate that you're right though. However, it will still be useful in my case, an AA that has minimal side effects for a 17 year old is still beneficial. I agree that we may not release it now. We may have better treatment within a couple of years, I think that we are between having few options and having many options. I'm just worried that I will lose my hair and effective treatments will be no use for me in the coming years.

[Swooping]

Chuckling here.. As expected obviously there was never a vehicle problem, but the concentration was. Sad that most of the baldies are so hopeful that they neglect the facts. Anyway 2 x 50mg a day is even more than I expected and kinda confirms the fact that RU58841 is stronger pound for pound than CB-03-01 together with the studies that are out.

2 x a day by the way is extremely stupid in my opinion btw. We are talking about convenience here. To be honest I don't see CB-03-01 for AGA going to hit the market now, mark my words lol. It's just a financial game played now.

Reason? They are way to late. If CB-03-01 were to be released realistically let's say in 2017-2018 they would only have MAX. a couple of years of revenue. Heck I would even say less than 5 years of revenue. Simply because over 10 years we'll definitely have more exciting things. It will be way outdated by then, and frankly it already is because we already have FIN/DUT/RU. NEXT.

[hellouser]

November 2015 is the end of Phase II, if the results are strong, which is expected with the 5% solution twice a day as Phase I results were very strong albeit with the charged machine thingy haha(cant remember the name), Phase III will begin very soon after, roughly 4-6 months i'd assume.

so realistically it will be out very late 2016- early 2017

FDA also takes its sweet time giving the green light on any new drug. For some reason they take ages in reviewing the product. IMO, 2016 is optimistic. 2017 is probably the absolute earliest.

[Justinian]

I'm just hoping that the acne product is being released with the same vehicle and percentage as the one that's being trialed for AA. If it's not, it's still the same molecule, so it can't be dangerous.

In that case, since it's considered safe, I'll just apply it on my scalp. The acne product is about a year ahead of the AA product so it should be out Late 2015ish?

Who can we ask to get the real answer for the acne product? It's entering phase 3, marketing should get kicked-off half way through...

I'm not sure about if it's the same vehicle, but I believe the acne one is 1% while the hair one is 5%. We won't know if it works (likely with less results than the hair solution) until we try it. Maybe it could be applied 3-4 times a day and work fine.

[NeedHairASAP]

did anybody get their vesapro from desmond?

[Gjm127]

I'm just hoping that the acne product is being released with the same vehicle and percentage as the one that's being trialed for AA. If it's not, it's still the same molecule, so it can't be dangerous.

In that case, since it's considered safe, I'll just apply it on my scalp. The acne product is about a year ahead of the AA product so it should be out Late 2015ish?

Who can we ask to get the real answer for the acne product? It's entering phase 3, marketing should get kicked-off half way through...

[rdawg]

What is the ETA for CB?

November 2015 is the end of Phase II, if the results are strong, which is expected with the 5% solution twice a day as Phase I results were very strong albeit with the charged machine thingy haha(cant remember the name), Phase III will begin very soon after, roughly 4-6 months i'd assume.

so realistically it will be out very late 2016- early 2017

[deuce]

What is the ETA for CB?

[rdawg]

So basically the benefit is only that it's stronger than FIN but with possibly more side effects. Orally I presume? I also presume a topical solution has been tried and failed...? How is it different than Avodart then?

Dutasteride is Avodart, its just that it is now getting officially approved, its nothing new, just that its the first drug in 17 years to be approved by the FDA!