We have a vehicle for CB-03-01: VERSAPRO

[petewete]

This made my day, great news Desmond and thank you for the effort. Hopefully this is it!

[Justinian]

Is there really that much of a risk for safety? I mean, this is a tested cream, and CB has gone under 2 safety trials and is currently in 2 more, with no signs of it not being safe. And, the science backs it up as being safe since it is metabolized to a safe substance in the bloodstream. I doubt it's possible that the combination of the two makes it not safe. The only risk I see is how effective it will be.

[jridd9]

this might be a silly question but is actually confirmed form of cb thats actually available to purchase. i see people claimed to have trailed it from that kane guy, and consequently it hasn't been effective due to vehicle. how do we know it's the vehicle causing all the issue with its effectiveness?

[stan]

people for whom fin is not working, this is worth a shot. At your own risk though.

[balding1983]

Thank you for posting this info Desmond. Indeed this is very encouraging news. Unfortunately, the last cosmo update I read said that they are testing a 5% anhydrous solution in their trials. Is that not correct? I suspect they chose this formulation as it is more convenient for use when compared to a lotion. Furthermore, versapro is a proprietary vehicle. So it is unlikely cosmo will choose it as a form of delivery.

[burtandernie]

Might work sounds a lot better than the typical vehicles everyone always talks about and that it looks like some guys that knew that what they were doing helped make it. Hopefully cosmo uses something like this in the actual product. Can we can topical spiro in this type of vehicle? I think chemical like spiro might be much stronger than thought if in a better vehicle like this possibly
Not something I am trying myself though. I will wait for a real company to do it

[StayThick]

The question remains, have you tried and started using this yourself Desmond?

If not, we will anxiously await a guinea pig(s) to do this to see it it holds any water...

I will patiently sit on the sidelines with my popcorn, as I will follow this closely.

[luca10]

Question:
True cb can cure seborrhea?

Traductor.

[Hairismylife]

What an exciting news Desmond!! We are close to a cure!

[Kiwi]

Have you noticed any results? Any shedding?

[wilymon]

Excuse my ignorance but what do you mean by "Compounding chemist"? Does that mean I can go to my local Walgreens and order these products or are there specific websites that do this?

[sosa56]

In all seriousness someone should contact cosmo with this information, you'd be surprised at the lack of communication/awareness within industry, they genuinely might not be aware of this product.

[Desmond84]

In Pharmacy we use the 'Doubling method' to add a powder into a cream. This video is a perfect tutorial for those wanting to give this a shot. This method ensures, the powder is evenly distributed into the cream.

Please note, Chrome browser doesn't allow you to see the links posted as videos. Make sure you use a different browser

[Desmond84]

It's interesting to note, Cosmo was showing efficacy by comparing CB-03-01 to Progesterone administered topically. We now have sufficient data that this vehicle is capable of getting Progesterone to the dermal layer and has all the ticks for carrying a drug with properties matching Cb-03-01.

Here's Medisca's webpage btw. Looks like they are also based in Canada which is excellent

http://www.medisca.com/en-us/LandingPage.aspx

[Desmond84]

Hey guys, sorry for not being here as often as I used to. Been busy doing a whole bunch of exciting stuff. So here's what I've been up to.

Around 6 months ago, when I got back from Korea, our company suddenly underwent new management and decided to provide compounding services at some of their larger Pharmacies and lucky enough, our Pharmacy was on that list.

For those not familiar with medical terms, "compounding" is when a Pharmacy prepares a medicinal product on site. Most of these are pessaries and creams but can include tablets, capsules, suppositories, lotions etc etc.

Anyways, long story short, I put my hand up to get the training which went on for a month and came across some amazing formulations and vehicles along the way. The whole time I was thinking about how many options we have at our fingertips to use as a vehicle for CB-03-01. We just didn't know about it.

And here's the interesting part, when we did the 'topical preparation' session, a particular vehicle kept on being mentioned called "Versapro" by a company called Medisca.

With its great carrying capacity and excellent emollient characteristics, MEDISCA’s VersaPro™ Cream Base is ideal for both pharmaceutical and cosmetic purposes. Its versatility relates in part to its increased pH stability and excellent compatibility with a wide range of active pharmaceutical ingredients. This unique oil-in-water emulsion is non-greasy, non-irritant and paraben-free. VersaPro™ is a highly moisturising cream formulated with excellent penetrating properties.

The studies they showed us involved using Versapro as a vehicle for Progesterone and it beat all other competitor's in terms of dosage delivered by a mile! I've attached these studies below for you to see. Not only that, it has crazy properties. As long as your active pharmaceutical ingredient (API) is a salt it is able to carry deep into the dermal layer. It has amazing penetrating properties and is ideal for steroidal and hormonal therapies. Ironically, CB-03-01 is in salt form and a steroid.

The results speak for themselves. Check it out:









Here's also the study testing its penetration properties using a steroidal active ingredient (Hydrocortisone).

http://conservancy.umn.edu/bitstream/handle/11299/116891/11-066%20Chemical%20Stability%20of%20Hydrocortisone%20article%2054.pdf;jsessionid=56C2969FC7EE2B6C0E712DCBA0B6DAC0?sequence=1

So anyways, after I came across all of this mind blowing information, I sat down with our lecturer and told him about the properties of CB-03-01 (molecular weight, pKa, pH, its salt form, etc) and he was pretty certain Versapro would get it where it needs to go (dermal layer). I'm also pretty sure it will be sufficient.

The lecturer also always pointed out, if you're not sure which one will do the job, most probably Versapro will! It's a no-brainer. Anyways guys that's all I gathered over the last few months of training. Hope it's been useful.

Oh also, any compounding chemist in Australia and USA can order this 'base' in for you. We have been ordering a ton in over the last month and it's cheap as chips. We get a 100g jar for about $20. All you need to do is weigh 2g of CB and mix it into it and your good to go. With regards to its consistency, it is definitely something you wanna apply overnight and wash off in the morning.

Good luck my brothers and please post any questions that you may have. I'll try my best to answer your questions.

Cheers.