adipose-derived stem cell protein extract

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  • nameless
    Senior Member
    • Feb 2013
    • 965

    #91
    Originally posted by beetee
    Perhaps I'm missing something, but are we mixing together opinions on the South Korean company and the results shown in the journal article? Unless I'm confused, they seem to be totally independent. If it's just because it sounds like they're using similar ideas, I really think they should be totally distinguished as it really makes all the difference in the world what the specifics are that are used in their separate processes.

    In regards to why this isn't in the news, the great majority of media sources (both in print and online) do not go out looking for news stories, at least about stuff like this. They get press releases from companies that are looking to get attention and then they write stories (and perhaps do further research) in response to those press releases. All of those stories about Cotsarelis were because he/Penn/Follica sent out announcements to major media sources alerting them to his "amazing" discoveries (sorry, I'm getting a little salty on Cotsarelis). Why the individuals involved in the PDF study that was linked to would not have gone through the effort to get their results more publicity, I really can't imagine. But as far as those looking at the lack of reporting as proof that it's not significant, all you have to do is look at all the psuedo-science and insignificant nonsense about hair loss that does get reported and you'll know that even if this is ultimately not that big of a deal, it certainly passes the bar that's been established by all the other BS, so it's not a matter of not being significant enough to be reported on.

    Oh, and anyone who thinks the regrowth in those pictures isn't significant must have a very full head of hair. I think you should get off this forum and go outside on a windy and sunny summer day and enjoy your thick locks.
    I think the reason this is not all over the news is that the people who were conducting the study were not trying to generate a big news story. They were just trying to test something.

    I am also concerned that we are mixing study results with the treatment being sold by a south korean company. I think we need to contact the people in the study and find out from them how we can get the exact same treatment that they used in their study. I think it's a mistake to try to get something similar that is different in any way. I think that we would want the exact same treatment in the study, admininstered the exact same way it's admininistered in the study, in the exact same dose and frequency. If it's even the slightest bit different then that could screw up the results.

    Comment

    • joachim
      Senior Member
      • May 2014
      • 559

      #92
      Originally posted by Swooping
      Yeah they are both similar only histogen uses dermal fibroblasts and this aape uses adipose tissue. And no, you don't have to use your own tissue.
      then from whom do they use the dermal fibroblasts and adipose tissue?
      i'm more confused than i was before =)

      Comment

      • hiko
        Junior Member
        • May 2014
        • 14

        #93
        Originally posted by Swooping
        Yeah they are both similar only histogen uses dermal fibroblasts and this aape uses adipose tissue. And no, you don't have to use your own tissue.
        Yeah, there is really no reason to hope this comes to market, since it is essentially another Histogen, and those guys are already balls deep into clinical trials while these guys haven't even started.

        The good thing here is that it shows injecting the right concentration of these growth factors into scalp produces really good results. As in, practically full blown cure type of results for people with early or moderate hair loss/recession. So when Histogen does come out, I really do believe it will be a game changer.

        I also think Histogen is desperate to bring their product to market asap, just based on the way the CEO talks. I think a lot of the other researchers are just focusing on ways to get NW7-->NW1 with a single miracle cure, rather than something that merely grows back more hair than fin/minox with minimal, noninvasive treatment. For us in the NW2-3 range, that's all we need.

        I mean, those crown regrowth pictures were impressive enough, but the young guy who nearly restored his hairline is as good or better than the best results I've seen from people using fin or dut. And we all know that very few people are lucky enough to get solid hairline regrowth from fin or dut. Based on these data, and what Histogen has already shown, it seems this method will work for the vast majority of patients.

        Comment

        • hellouser
          Senior Member
          • May 2012
          • 4419

          #94
          Originally posted by hiko
          Yeah, there is really no reason to hope this comes to market, since it is essentially another Histogen, and those guys are already balls deep into clinical trials while these guys haven't even started.

          The good thing here is that it shows injecting the right concentration of these growth factors into scalp produces really good results. As in, practically full blown cure type of results for people with early or moderate hair loss/recession. So when Histogen does come out, I really do believe it will be a game changer.

          I also think Histogen is desperate to bring their product to market asap. I think a lot of the other researchers are just focusing on ways to get NW7-->NW1 with a single miracle cure, rather than something that merely grows back more hair than fin/minox with minimal, noninvasive treatment. For us in the NW2-3 range, that's all we need.
          It'd benefit NW4-5 as well as they could go in for an HT and get on with their lives.

          Comment

          • nameless
            Senior Member
            • Feb 2013
            • 965

            #95
            Originally posted by downandout
            "Patient satisfaction was lower with mesotherapy treatment than with HARG therapy. Some patients moved from mesotherapy treatment to HARG therapy with stem cell protein. The stem cell proteins are the most essential components of this hair regrowth therapy. Treatment using only the vitamin mixture was not more effective than the stem cell protein treatment in our recent double-blind test. "

            Seems to me that if you want the real stuff that was actually used in the study then you are going to have to go to a clinic to get it. The problem is, where can we get this product that contains the HARG THERAPY that was the same thing used in the studies.
            And you are right. You want it with the HARG therapy. You want it exactly as it is in the study.

            Comment

            • Thinning87
              Senior Member
              • Dec 2012
              • 839

              #96
              Originally posted by hiko
              Yeah, there is really no reason to hope this comes to market, since it is essentially another Histogen, and those guys are already balls deep into clinical trials while these guys haven't even started.

              The good thing here is that it shows injecting the right concentration of these growth factors into scalp produces really good results. As in, practically full blown cure type of results for people with early or moderate hair loss/recession. So when Histogen does come out, I really do believe it will be a game changer.

              I also think Histogen is desperate to bring their product to market asap, just based on the way the CEO talks. I think a lot of the other researchers are just focusing on ways to get NW7-->NW1 with a single miracle cure, rather than something that merely grows back more hair than fin/minox with minimal, noninvasive treatment. For us in the NW2-3 range, that's all we need.

              I mean, those crown regrowth pictures were impressive enough, but the young guy who nearly restored his hairline is as good or better than the best results I've seen from people using fin or dut. And we all know that very few people are lucky enough to get solid hairline regrowth from fin or dut. Based on these data, and what Histogen has already shown, it seems this method will work for the vast majority of patients.
              Bro that was a woman's picture. Histogen does work, but it's just alright for men. It's somewhat better than propecia and rogaine, and it's noninvasive. But that's all it is. Would have been perfect when I was 24

              Comment

              • hiko
                Junior Member
                • May 2014
                • 14

                #97
                Originally posted by Thinning87
                Bro that was a woman's picture. Histogen does work, but it's just alright for men. It's somewhat better than propecia and rogaine, and it's noninvasive. But that's all it is. Would have been perfect when I was 24
                Nope. Look again. That was a guy. I'm referring to the patient who had hairline regrowth.

                Actually half of the study patients were male, and results were positive in everyone. I don't know why you think this only applies to women.

                I can only think of two people who had comparable results at the hairline on current treatments. Histogen might not be a cure for bald people, but it is much better than what we have right now.

                Comment

                • nameless
                  Senior Member
                  • Feb 2013
                  • 965

                  #98
                  Originally posted by hiko
                  Nope. Look again. That was a guy. I'm referring to the patient who had hairline regrowth.

                  Actually half of the study patients were male, and results were positive in everyone. I don't know why you think this only applies to women.

                  I can only think of two people who had comparable results at the hairline on current treatments. Histogen might not be a cure for bald people, but it is much better than what we have right now.
                  Histogen might be more effective if you had it injected more than once.

                  Also, this adipose derived growth factors might be just as good if not better.

                  Comment

                  • beetee
                    Senior Member
                    • Nov 2013
                    • 187

                    #99
                    Originally posted by nameless
                    I think the reason this is not all over the news is that the people who were conducting the study were not trying to generate a big news story. They were just trying to test something.

                    I am also concerned that we are mixing study results with the treatment being sold by a south korean company. I think we need to contact the people in the study and find out from them how we can get the exact same treatment that they used in their study. I think it's a mistake to try to get something similar that is different in any way. I think that we would want the exact same treatment in the study, admininstered the exact same way it's admininistered in the study, in the exact same dose and frequency. If it's even the slightest bit different then that could screw up the results.
                    I have sent an email to one of the authors of the study asking for clarification on a few points. I have no idea if he will respond but if he does I will certainly make a post about it.

                    Upon closer examination, there are a few details of the article that cause me some concern. For one, the journal does not seem to be widely subscribed to by serious academic universities, and the part where they state that they just threw a bunch of potentially hair related vitamins in the mix because they figured it might help seemed strange. That being said, unless those pictures are straight up doctored, I really don't see how this can be dismissed at this point.

                    Comment

                    • Swooping
                      Senior Member
                      • May 2014
                      • 794

                      They do speak of a "commercial" AAPE product in the study..? The study is from 2012..

                      Comment

                      • Alias123
                        Member
                        • Jan 2013
                        • 79

                        any updates from the korean contact? this still looks more intreseting and closer then anything else on this forum atm

                        Comment

                        • HairBane
                          Senior Member
                          • Apr 2013
                          • 300

                          Comment

                          • nameless
                            Senior Member
                            • Feb 2013
                            • 965

                            Originally posted by Alias123
                            any updates from the korean contact? this still looks more intreseting and closer then anything else on this forum atm
                            I agree. I would like to see what happens if we were to do the EXACT same treatment that's in the study plus perhaps find a way to get our hands on a DKK1 antagonist to use at the same time. I wonder...

                            Comment

                            • Swooping
                              Senior Member
                              • May 2014
                              • 794

                              Originally posted by Alias123
                              any updates from the korean contact? this still looks more intreseting and closer then anything else on this forum atm
                              No response yet i just shot him another e-mail . I'll let you guys know when i got more information.

                              Comment

                              • Swooping
                                Senior Member
                                • May 2014
                                • 794

                                There were quite some presentations about it at the hair congress too;

                                P080
                                HAIR GROWTH STIMULATION BY ADIPOSE TISSUE-DERIVED STEM CELLS
                                Gyeong-Hun PARK

                                * P153 (FC4) ADIPOSE DERIVED STEM CELLS AND GROWTH FACTORS APPLIED ON HAIR TRANSPLANTATION. FOLLOW-UP OF CLINICAL OUTCOME
                                Federica ZANZOTTERA

                                P222 STUDY ON HAIR-INDUCING CAPACITY OF HUMAN ADIPOSE-DERIVED STEM CELLS (ADSC)
                                Chang Hoon SEO

                                P231 CLINICAL USE OF CONDITIONED MEDIA OF ADIPOSE TISSUE-DERIVED STEM CELLS IN FEMALE PATTERN HAIR LOSS: A RETROSPECTIVE CASE SERIES STUDY
                                Hyoseung SHIN


                                So i guess it surely grows SOME hair.. The interest is there.

                                Comment

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