WCHR 2014 Presentations (Community-funded)

[deuce]

Man. I figured it would be ten years at least, but I knew everyone here had in the back of their mine that somehow someone would give some news that they would have a product in a couple of years. Seems to me that it is great that everyone is progressing in research, but all it is is research it is not helping us now. I think what myself and others need to focus on is how we are going to keep our existing hair for the next multiple years? I have no clue. It sucks if you cannot use FIN.

[JZA70]

Seems to me that it is great that everyone is progressing in research, but all it is is research it is not helping us now.

Well that's all that's really going to happen. Even once they can grow thousands of hairs for us like its nothing, we still have to wait for trials and what not. Remaining research + trials = long time.

You're being mislead if you think you'll be cured within 10 years.

[Thinning87]

Well, technically, Follica in June 2013 implied they would beging testing fgf9 at the preclinical level. Because they probably would have started before or, the latest, a few months after June 2013, they should have some kind of idea of what fgf9 can do.

Maybe this is what Cotsarelis was referring to when talking to Desmond... Yeah they could finish what they started with the PGD2 blockers and give us some product that is somewhat better than what's currently available... OR... Start over from preclinical with fgf9. Which explains why they would need a whole new $20 million to carry this all the way to phase 3 - and years.

To me this makes sense. It would explain why they needed to publicize their discovery with the June 2013 interviews to the press.

[fuzzyballs]

Well, technically, Follica in June 2013 implied they would beging testing fgf9 at the preclinical level. Because they probably would have started before or, the latest, a few months after June 2013, they should have some kind of idea of what fgf9 can do.

Maybe this is what Cotsarelis was referring to when talking to Desmond... Yeah they could finish what they started with the PGD2 blockers and give us some product that is somewhat better than what's currently available... OR... Start over from preclinical with fgf9. Which explains why they would need a whole new $20 million to carry this all the way to phase 3 - and years.

To me this makes sense. It would explain why they needed to publicize their discovery with the June 2013 interviews to the press.

I'm not so sure anymore, $2M - $20M, it all seems totally arbitrary. I think he wants a new Porche and to continue his lifestyle on the hollywood hills.

Histogen has shown photos of regrowth, I'm assuming that it would at the very least HALT hairloss. Why back anything else.

Also crowdfunding!?! Good luck... I'd only pay the scientists upon the delivery of results. In the meantime they can live off minimum wage. Give them something to strive for.

[fuzzyballs]

@Desmond are Histogen attending this one?

[Thinning87]

I'm not so sure anymore, $2M - $20M, it all seems totally arbitrary. I think he wants a new Porche and to continue his lifestyle on the hollywood hills.

Histogen has shown photos of regrowth, I'm assuming that it would at the very least HALT hairloss. Why back anything else.

Also crowdfunding!?! Good luck... I'd only pay the scientists upon the delivery of results. In the meantime they can live off minimum wage. Give them something to strive for.

That's the right attitude........ For another 30 years of propecia and rogaine!

[fuzzyballs]

That's the right attitude........ For another 30 years of propecia and rogaine!

Brother, I know you might think I'm being negative, but I'm not. I have had a hair transplant by Cooley, I have have a dumb FUT scare and I was told that I'd be okay even though I get Fin side effects. I'm not okay and hair loss is catching up!

Trust me... nobody wants to arrest hair loss like I do. I think Histogen is the closest we have until Desmond tells us otherwise. I cannot reconcile throwing more money at people who've already had TONS of money thrown at them.

More fool me maybe?

[TravisB]

We would have better luck crowdfunding Lauster or the Chinese guys than the scammer Cotsarelis.

Cotsarelis comes up with some bullshit "breakthrough discovery" every few years and there are still no results of any of his work.

And his statement about only $2 million needed to bring treatment better than Propecia + Minox, and $20 million needed for a full cure is a joke and nail to his coffin in my book

If he REALLY had something good up his sleeve, then getting $2 million would be as easy as snap of a finger.

He's a bullshitter

[walrus]

That's awesome! Having a testbed like that will FINALLY determine efficacy of compounds before going to trials. Hell, I wonder if such topicals will even need to be further tested on humans if we have skin and follicles to work with. Clinical trials could be reduced drastically.

This can be/is already done with explanted human hair follicles. The advantage would be efficiency.

[walrus]

I'm not so sure anymore, $2M - $20M, it all seems totally arbitrary. I think he wants a new Porche and to continue his lifestyle on the hollywood hills.

Histogen has shown photos of regrowth, I'm assuming that it would at the very least HALT hairloss. Why back anything else.

Also crowdfunding!?! Good luck... I'd only pay the scientists upon the delivery of results. In the meantime they can live off minimum wage. Give them something to strive for.

Make up your mind. Are researchers living the Hollywood lifestyle or is it minimum wage?

[walrus]

Cotsarelis comes up with some bullshit "breakthrough discovery" every few years and there are still no results of any of his work.

Have you actually read any of his publications to make this assertion? If you think they are bullshit you are welcome to write your own peer reviewed rebuttal, you could even attend internationally recognised conferences yourself.

[jay woo]

Is the 2 million and 20 million figure to develop a treatment that will still require passing off all trial phases. I would assume that this is the case and is the reason that funding is not easy to obtain.

Clinical trails are what cost the money, I do not believe any of the treatments proposed can be used to treat other conditions. This means that if the treatment fails it is wasted money for the company. It is not possible to trial the treatment on another condition and hope for a return on investment.

[Arashi]

So Desmond, how did it go today ?

[artika]

It's almost 11 o'clock over there, maybe he's done for today :S

[fuzzyballs]

Make up your mind. Are researchers living the Hollywood lifestyle or is it minimum wage?

What I mean, is that if we're funding him, he should be on minimum wage until we see results. UNLIKE now. Which seems to be that researchers (and this is something I picked up on from @hellouser) is that they seem quite comfortable researching and NOT taking things to market.

So up until now, these researchers get their nice cars and hollywood homes, under my funding regime they would have minimum wage UNTIL they deliver. Which is how it should be.

Furthermore anybody who's familiar with with crowd funding is that the pledgers get something in return.

If Cotsarelis is so confident that he can make something we should ALL get free cure for making him a many times over multi-million-billionere. Of course that isnt going to happen...