WCHR 2014 Presentations (Community-funded)

[bananana]

I do not want to be rude or anything, but what are you doing here then?
I never understood your posts and have the feeling that you work for some kind or hair transplant surgeon. the way you present yourself on this forum is just weird man.
a) I get it that you spoke with Dr Xu and think that he is the best of the best, but there are also other researchers out there
b) Dr Gardner answered our questions and the subtext was, in my opion, "if somebody cracks it things can develop fast". angeling, positioning, donīt you think people thought about such things at the beginning of their journey.
c) Why even think about a CURE now, first there will be treatments. Something like Replicel, even with their current 10 - 15 or maybe 20% results, can give you solid results, this is great stuff. Maybe the germans have something cool. Maybe CB can replace Propecia and some kind of PGD2 inhibitor (bimatoprost) hits the market sooner than you think.

I just donīt get the negative guys on here. If I would think this is a lost I would not spend as much time on here as you do.

Exactly.

[sascha]

the more i think about it, the more i'm sure that no one is gonna cure hairloss until they can do it with gene editing in the far future. Next time you see a totally bald man, just think about it- Even if you manage to make a new follicle in a lab (big if still), you still have to get that thing to a) grow in the right direction and cycle (who in the hell know how they can accomplish this, the only way i can think is to grow an entire follicular unit and implant each one carefully like a HT) and b) get that thing to thrive in fibrotic, totally inhospitable bald tissue, when your entire body, and all the cells in your skin are telling that thing to fall apart, as well as telling all the surrounding fat and tissues to not support it and fall apart too. Curing baldness is like curing aging or curing the length of someones legs or the color of their skin. So much is involved in giving you your exact pattern of hair loss, i think that until they are able to completely regrow an entire scalp, with skin and all supporting structures, that this is all pretty much useless.

It will be done, but certainly not anytime that matters to us. sure, treatments like replicel and CB and such might help to lose hair more slowly or lose less, but even those are a ways off, and at least in my opinion, running shit on my head and paying lots of money to keep treating something that is inevitable anyway is far less appealing than just shaving the lot off and saying screw it. stem cell science is certainly interesting, but all this optimistic cure talk just because someone managed to not lose all the inductivity of one cell type is nonsense. when you really look at a bald scalp you can see how far off we still are, no amount of DP cells are gonna give you a perfect head of hair.

I do not want to be rude or anything, but what are you doing here then?
I never understood your posts and have the feeling that you work for some kind or hair transplant surgeon. the way you present yourself on this forum is just weird man.
a) I get it that you spoke with Dr Xu and think that he is the best of the best, but there are also other researchers out there
b) Dr Gardner answered our questions and the subtext was, in my opion, "if somebody cracks it things can develop fast". angeling, positioning, donīt you think people thought about such things at the beginning of their journey.
c) Why even think about a CURE now, first there will be treatments. Something like Replicel, even with their current 10 - 15 or maybe 20% results, can give you solid results, this is great stuff. Maybe the germans have something cool. Maybe CB can replace Propecia and some kind of PGD2 inhibitor (bimatoprost) hits the market sooner than you think.

I just donīt get the negative guys on here. If I would think this is a lost I would not spend as much time on here as you do.

[JZA70]

get that thing to thrive in fibrotic, totally inhospitable bald tissue, when your entire body, and all the cells in your skin are telling that thing to fall apart, as well as telling all the surrounding fat and tissues to not support it and fall apart too.

Considering current transplanted hairs survive fine in the recipient area, I don't think this will be a problem.

[sdsurfin]

meh

the more i think about it, the more i'm sure that no one is gonna cure hairloss until they can do it with gene editing in the far future. Next time you see a totally bald man, just think about it- Even if you manage to make a new follicle in a lab (big if still), you still have to get that thing to a) grow in the right direction and cycle (who in the hell know how they can accomplish this, the only way i can think is to grow an entire follicular unit and implant each one carefully like a HT) and b) get that thing to thrive in fibrotic, totally inhospitable bald tissue, when your entire body, and all the cells in your skin are telling that thing to fall apart, as well as telling all the surrounding fat and tissues to not support it and fall apart too. Curing baldness is like curing aging or curing the length of someones legs or the color of their skin. So much is involved in giving you your exact pattern of hair loss, i think that until they are able to completely regrow an entire scalp, with skin and all supporting structures, that this is all pretty much useless.

It will be done, but certainly not anytime that matters to us. sure, treatments like replicel and CB and such might help to lose hair more slowly or lose less, but even those are a ways off, and at least in my opinion, running shit on my head and paying lots of money to keep treating something that is inevitable anyway is far less appealing than just shaving the lot off and saying screw it. stem cell science is certainly interesting, but all this optimistic cure talk just because someone managed to not lose all the inductivity of one cell type is nonsense. when you really look at a bald scalp you can see how far off we still are, no amount of DP cells are gonna give you a perfect head of hair.

[35YrsAfter]

Most likely without the help of a hair surgeon. It's obvious.

The best-case delivery IMO would be a topical + Derma Roller. For anyone interested, here is one possible delivery method:
Skin Printer

35YrsAfter also posts as CITNews and works at Dr. Cole's office - forhair.com - Cole Hair Transplant 1070 Powers Place Alpharetta, Georgia 30009 - Phone 678-566-1011 - email 35YrsAfter at chuck@forhair.com
The contents of my posts are my opinions and not medical advice. Please feel free to call or email me with any questions. Ask for Chuck

[hellouser]

Oh also, i have some promising news for everyone :-) as i said before the german team have progressed significantly and under the radar for over 5 years now. i just received an email for dr lindner that they will be launching their hair multiplication website in the next 4 weeks, which will explain a lot of their work and findings. That is definitely a good sign in my eyes :-)

i can't wait to see this!!!!

[stan]

Just because it is the TU Berlin(technical university). The news per se donīt have something to do with it

oh i c . . :P. HOPE.

[hellouser]

One of Dr. Lauster's team members has this site:

http://www.tissuse.com/

Here's some technical detail about the site:

http://whois.domaintools.com/tissuse.com

Notice that it was setup in 2010, around the time they made the hair follicle discovery??

[joachim]

Just because it is the TU Berlin(technical university). The news per se donīt have something to do with it

nice if we have some kind of insider at the TU Berlin =)
but i think the new website is at least a good start for more transparency.
keep us updated with whatever info you can get, especially if you live in Berlin.

[sascha]

whats it got to do with IT? sorry for asking a lame Q

Just because it is the TU Berlin(technical university). The news per se donīt have something to do with it

[stan]

Hey guys, I spoke with my friend from back in the day. He studies IT in Berlin and he said that rumors go around that "the hair loss section has something to present soon". Probably he meant the thing with the website Desmond mentioned. Just wanted to tell you guys. Cheers
P.S: Donīt be always so pessimistic

whats it got to do with IT? sorry for asking a lame Q

[sascha]

Hey guys, I spoke with my friend from back in the day. He studies IT in Berlin and he said that rumors go around that "the hair loss section has something to present soon". Probably he meant the thing with the website Desmond mentioned. Just wanted to tell you guys. Cheers
P.S: Donīt be always so pessimistic

[Arashi]

Thanks for the update desmond. However, this is the kind of buoyantly optimistic post that you often make without really backing up anything you are saying. It gets us all excited, and then when we are left to see the videos/talk to the researchers etc, it all seems not quite so great. Where are you basing this idea that most researchers are 2-3 years away from a final cure? According to dr. gardner and dr. xu (two of the top guys) they have no idea whether they are even close to making a working follicle. Their best guess is someone will make a follicle in the next ten years. I'm not saying you're wrong, but none of the videos posted so far shows us being anywhere nearer than probably decades from a real cure. Right now all they are able to do is restore some inductivity to hair cells and grow some patchy clumps of fibers in mice. how does this translate to a cure in 3 years? even if we make working follicles, who knows how many obstacles still exist.

I'm pretty tired of reading all this cure is coming soon bollocks, when there is a new roadblock at every step, not to mention endless trials (which are necessary mostly). If you're going to say something like this, then let us know why! so far none of the guys we have talked to has that kind of optimism, or is even willing to venture a guess at when a treatment is coming. I'm looking forward to the presentation from lauster, but for real, if it is anything like the others i'm gonna be pretty bummed. Sometimes I feel like you (desmond) project your own optimism onto the people you talk to, and whatever they told you has been amplified to hopes that are unfounded. I'll believe a cure is coming in three years when I hear a single one of these researchers say it themselves. And more specifically, when I hear them say that they will be growing new hair on bald people in three years, not hopefully making ONE new follicle in a lab that may or may not survive on someones scalp.

I definitely can see where you're coming from. I'm an optimistic guy myself by nature and it's not hard to see Desmond is one too But that can lead to disappointments every now and then. Although the whole WCHR project has been a great success for us (we finally understand where we are and even Dr Gardner came to this board to answer any questions we had, who would have thought that to be possible! All thanks to Desmond !), the presentations itself where a bit disappointing so far and no breakthrough like Jahoda's at WCHR 2013 was reported.

Dr Gardner said he doesn't want to make any predictions. I gathered he basically says the 'missing link' could be found tomorrow and for all we know we can grow perfect follicles tomorrow or there might be tons of roadblocks down the road from hereon. We just don't know. All we know is that we're making solid progress. So while 2-3 years certainly might be correct, I haven't seen any evidence so far that justifies that assumption

[sdsurfin]

ugh

Thanks for the update desmond. However, this is the kind of buoyantly optimistic post that you often make without really backing up anything you are saying. It gets us all excited, and then when we are left to see the videos/talk to the researchers etc, it all seems not quite so great. Where are you basing this idea that most researchers are 2-3 years away from a final cure? According to dr. gardner and dr. xu (two of the top guys) they have no idea whether they are even close to making a working follicle. Their best guess is someone will make a follicle in the next ten years. I'm not saying you're wrong, but none of the videos posted so far shows us being anywhere nearer than probably decades from a real cure. Right now all they are able to do is restore some inductivity to hair cells and grow some patchy clumps of fibers in mice. how does this translate to a cure in 3 years? even if we make working follicles, who knows how many obstacles still exist.

I'm pretty tired of reading all this cure is coming soon bollocks, when there is a new roadblock at every step, not to mention endless trials (which are necessary mostly). If you're going to say something like this, then let us know why! so far none of the guys we have talked to has that kind of optimism, or is even willing to venture a guess at when a treatment is coming. I'm looking forward to the presentation from lauster, but for real, if it is anything like the others i'm gonna be pretty bummed. Sometimes I feel like you (desmond) project your own optimism onto the people you talk to, and whatever they told you has been amplified to hopes that are unfounded. I'll believe a cure is coming in three years when I hear a single one of these researchers say it themselves. And more specifically, when I hear them say that they will be growing new hair on bald people in three years, not hopefully making ONE new follicle in a lab that may or may not survive on someones scalp.

[nameless]

At least its plural; teams.

We dont have to hope for just ONE team.

Hellouser don't you think that there's a real probability that adipose stem cell extract (AAPE) could give us solid cover while we wait for the cell based therapies to be perfected and get to market?